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Justifying draconian measures during the Covid-19 pandemic was difficult not only because of the restriction of individual rights, but also because of its economic impact. The objective of this work is to present a machine learning approach…

机器学习 · 计算机科学 2020-11-30 Santiago Cortes , Yullys M. Quintero

Context: Utilization of operating theaters is a major cost driver in hospitals. Optimizing this variable through optimized surgery schedules may significantly lower cost and simultaneously improve medical outcomes. Previous studies proposed…

应用统计 · 统计学 2025-09-05 Harald Störrle , Anastasia Hort

In response to the COVID-19 pandemic and the potential threat of future epidemics caused by novel viruses, we developed a flexible framework for modeling disease intervention effects. This tool is intended to aid decision makers at multiple…

多智能体系统 · 计算机科学 2023-08-22 Karleigh Pine , Razvan Veliche , Jared Bennett , Joel Klipfel

Epidemiologists model the dynamics of epidemics in order to propose control strategies based on pharmaceutical and non-pharmaceutical interventions (contact limitation, lock down, vaccination, etc). Hand-designing such strategies is not…

Numerical QCD is often extremely resource demanding and it is not rare to run hundreds of simulations at the same time. Each of these can last for days or even months and it typically requires a job-script file as well as an input file with…

高能物理 - 格点 · 物理学 2018-04-18 Alessandro Sciarra

We highlight the usefulness of city-scale agent-based simulators in studying various non-pharmaceutical interventions to manage an evolving pandemic. We ground our studies in the context of the COVID-19 pandemic and demonstrate the power of…

Accurate modeling of the patient flow within an Emergency Department (ED) is required by all studies dealing with the increasing and well-known problem of overcrowding. Since Discrete Event Simulation (DES) models are often adopted with the…

最优化与控制 · 数学 2021-02-02 A. De Santis , T. Giovannelli , S. Lucidi , M. Messedaglia , M. Roma

The estimation of unknown parameters in simulations, also known as calibration, is crucial for practical management of epidemics and prediction of pandemic risk. A simple yet widely used approach is to estimate the parameters by minimizing…

统计方法学 · 统计学 2023-06-26 Chih-Li Sung , Ying Hung

Quantum cloud computing is an emerging computing paradigm that allows seamless access to quantum hardware as cloud-based services. However, effective use of quantum resources is challenging and necessitates robust simulation frameworks for…

新兴技术 · 计算机科学 2024-05-03 Hoa T. Nguyen , Muhammad Usman , Rajkumar Buyya

For operating rooms (ORs) and hospitals, inventory management of surgical instruments and material handling decisions of perioperative services are critical to hospitals' service levels and costs. However, efficiently integrating these…

最优化与控制 · 数学 2020-06-15 Amogh Bhosekar , Sandra Eksioglu , Tugce Isik

Epidemiological models can not only be used to forecast the course of a pandemic like COVID-19, but also to propose and design non-pharmaceutical interventions such as school and work closing. In general, the design of optimal policies…

最优化与控制 · 数学 2023-04-06 Jan-Hendrik Niemann , Samuel Uram , Sarah Wolf , Nataša Djurdjevac Conrad , Martin Weiser

Our main purpose is to compare classical nonself-centered, two-signal theoretical models of the adaptive immune system with a novel, self-centered, one-signal model developed by our research group. Our model hypothesizes that the immune…

分子网络 · 定量生物学 2020-12-02 Tamás Szabados , Csaba Kerepesi , Tibor Bakács

Cloud computing based systems, that span data centers, are commonly deployed to offer high performance for user service requests. As data centers continue to expand, computer architects and system designers are facing many challenges on how…

分布式、并行与集群计算 · 计算机科学 2019-10-08 Fan Yao , Kathy Ngyugen , Sai Santosh Dayapule , Jingxin Wu , Bingqian Lu , Suresh Subramaniam , Guru Venkataramani

The onset of the COVID-19 pandemic drove a widespread, often uncoordinated effort by research groups to develop mathematical models of SARS-CoV-2 to study its spread and inform control efforts. The urgent demand for insight at the outset of…

Scientific advice to the UK government throughout the COVID-19 pandemic has been informed by ensembles of epidemiological models provided by members of the Scientific Pandemic Influenza group on Modelling (SPI-M). Among other applications,…

应用统计 · 统计学 2021-08-13 D. S. Silk , V. E. Bowman , D. Semochkina , U. Dalrymple , D. C. Woods

Failures in clusters running large-scale AI workloads can result in decreased utilization. Because the cost of a failure in such AI workloads is high (as it requires restarting the entire job from a previous checkpoint), there are many…

分布式、并行与集群计算 · 计算机科学 2026-05-05 Karthik Pattabiraman , Mihir Patel , Fred Lin

Cloud computing aims to power the next generation data centers and enables application service providers to lease data center capabilities for deploying applications depending on user QoS (Quality of Service) requirements. Cloud…

分布式、并行与集群计算 · 计算机科学 2009-07-29 Rajkumar Buyya , Rajiv Ranjan , Rodrigo N. Calheiros

Since the first wave of the COVID-19 pandemic, governments have applied restrictions in order to slow down its spreading. However, creating such policies is hard, especially because the government needs to trade-off the spreading of the…

机器学习 · 计算机科学 2022-05-03 Leonardo Lucio Custode , Giovanni Iacca

This study investigated the performance, explainability, and robustness of deployed artificial intelligence (AI) models in predicting mortality during the COVID-19 pandemic and beyond. The first study of its kind, we found that Bayesian…

机器学习 · 计算机科学 2023-11-30 Jacob R. Epifano , Stephen Glass , Ravi P. Ramachandran , Sharad Patel , Aaron J. Masino , Ghulam Rasool

Scientific applications produce a huge amount of data, which imposes serious management and analysis challenges. In particular, limitations in current database management systems prevent their adoption in simulation applications, in which…

数据库 · 计算机科学 2019-03-18 Hermano Lustosa , Fabio Porto