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Advances in data collecting technologies in genomics have significantly increased the need for tools designed to study the genetic basis of many diseases. Effective statistical methods should excel in both prediction accuracy and biomarker…

统计方法学 · 统计学 2025-11-13 Anthony-Alexander Christidis , Stefan Van Aelst , Ruben Zamar

In this work, we focus on the problem of learning a classification model that performs inference on patient Electronic Health Records (EHRs). Often, a large amount of costly expert supervision is required to learn such a model. To reduce…

机器学习 · 计算机科学 2015-07-30 Eric Heim , Milos Hauskrecht

We address the challenge of conducting inference for a categorical treatment effect related to a binary outcome variable while taking into account high-dimensional baseline covariates. The conventional technique used to establish…

统计方法学 · 统计学 2024-11-27 Abhishek Ojha , Naveen N. Narisetty

We consider high-dimensional inference for potentially misspecified Cox proportional hazard models based on low dimensional results by Lin and Wei [1989]. A de-sparsified Lasso estimator is proposed based on the log partial likelihood…

统计理论 · 数学 2018-11-02 Shengchun Kong , Zhuqing Yu , Xianyang Zhang , Guang Cheng

An important challenge in statistical analysis concerns the control of the finite sample bias of estimators. For example, the maximum likelihood estimator has a bias that can result in a significant inferential loss. This problem is…

统计理论 · 数学 2019-11-04 Stéphane Guerrier , Mucyo Karemera , Samuel Orso , Maria-Pia Victoria-Feser

We propose a new estimator for the high-dimensional linear regression model with observation error in the design where the number of coefficients is potentially larger than the sample size. The main novelty of our procedure is that the…

统计方法学 · 统计学 2019-09-09 Alexandre Belloni , Abhishek Kaul , Mathieu Rosenbaum

We propose an evaluation framework for class probability estimates (CPEs) in the presence of label uncertainty, which is commonly observed as diagnosis disagreement between experts in the medical domain. We also formalize evaluation metrics…

机器学习 · 统计学 2021-03-23 Takahiro Mimori , Keiko Sasada , Hirotaka Matsui , Issei Sato

We examine the linear regression problem in a challenging high-dimensional setting with correlated predictors where the vector of coefficients can vary from sparse to dense. In this setting, we propose a combination of probabilistic…

统计方法学 · 统计学 2025-05-13 Roman Parzer , Peter Filzmoser , Laura Vana-Gür

This work addresses the problem of high-dimensional classification by exploring the generalized Bayesian logistic regression method under a sparsity-inducing prior distribution. The method involves utilizing a fractional power of the…

统计理论 · 数学 2024-03-20 The Tien Mai

Minimization of the (regularized) entropy of classification probabilities is a versatile class of discriminative clustering methods. The classification probabilities are usually defined through the use of some classical losses from…

统计理论 · 数学 2021-12-17 Edouard Genetay , Adrien Saumard , Rémi Coulaud

We consider a novel Bayesian approach to estimation, uncertainty quantification, and variable selection for a high-dimensional linear regression model under sparsity. The number of predictors can be nearly exponentially large relative to…

统计方法学 · 统计学 2025-02-28 Samhita Pal , Subhashis Ghoshal

In this paper, we introduce an innovative testing procedure for assessing individual hypotheses in high-dimensional linear regression models with measurement errors. This method remains robust even when either the X-model or Y-model is…

统计方法学 · 统计学 2025-01-14 Shijie Cui , Xu Guo , Songshan Yang , Zhe Zhang

This paper presents a novel method to make statistical inferences for both the model support and regression coefficients in a high-dimensional logistic regression model. Our method is based on the repro samples framework, in which we…

统计方法学 · 统计学 2024-03-18 Xiaotian Hou , Linjun Zhang , Peng Wang , Min-ge Xie

We study the problem of estimation and testing in logistic regression with class-conditional noise in the observed labels, which has an important implication in the Positive-Unlabeled (PU) learning setting. With the key observation that the…

统计方法学 · 统计学 2020-08-14 Hyebin Song , Ran Dai , Garvesh Raskutti , Rina Foygel Barber

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

定量方法 · 定量生物学 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

Motivated by the challenges in analyzing gut microbiome and metagenomic data, this work aims to tackle the issue of measurement errors in high-dimensional regression models that involve compositional covariates. This paper marks a…

统计方法学 · 统计学 2024-09-13 Huali Zhao , Tianying Wang

Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and…

Accurate simulation of complex physical systems enables the development, testing, and certification of control strategies before they are deployed into the real systems. As simulators become more advanced, the analytical tractability of the…

机器人学 · 计算机科学 2020-05-27 Lucas Barcelos , Rafael Oliveira , Rafael Possas , Lionel Ott , Fabio Ramos

Employee theft and dishonesty is a major contributor to loss in the retail industry. Retailers have reported the need for more automated analytic tools to assess the liability of their employees. In this work, we train and optimize several…

机器学习 · 计算机科学 2018-03-30 Richard R. Yang , Mike Borowczak

A class of simultaneous equation models arise in the many domains where observed binary outcomes are themselves a consequence of the existing choices of of one of the agents in the model. These models are gaining increasing interest in the…

计量经济学 · 经济学 2025-12-30 Shakeeb Khan , Elie Tamer , Qingsong Yao