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Neuropathic pain, affecting up to 10% of adults, remains difficult to treat due to limited therapeutic efficacy and tolerability. Although resting-state functional MRI (rs-fMRI) is a promising non-invasive measurement of brain biomarkers to…

机器学习 · 计算机科学 2025-03-04 Wenrui Fan , L. M. Riza Rizky , Jiayang Zhang , Chen Chen , Haiping Lu , Kevin Teh , Dinesh Selvarajah , Shuo Zhou

Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome. Early diagnosis and precise treatment are essential for ASD patients. Although researchers have built many analytical models, there has been limited progress in…

神经元与认知 · 定量生物学 2018-10-30 Juntang Zhuang , Nicha C. Dvornek , Xiaoxiao Li , Pamela Ventola , James S. Duncan

Functional magnetic resonance imaging (fMRI) has provided invaluable insight into our understanding of human behavior. However, large inter-individual differences in both brain anatomy and functional localization after anatomical alignment…

应用统计 · 统计学 2021-11-03 Guoqing Wang , Abhirup Datta , Martin A. Lindquist

Multisequence Magnetic Resonance Imaging (MRI) provides a more reliable diagnosis in clinical applications through complementary information across sequences. However, in practice, the absence of certain MR sequences is a common problem…

图像与视频处理 · 电气工程与系统科学 2025-10-21 Jihoon Cho , Jonghye Woo , Jinah Park

We present a computational framework for analysis and visualization of non-linear functional connectivity in the human brain from resting state functional MRI (fMRI) data for purposes of recovering the underlying network community structure…

神经与进化计算 · 计算机科学 2014-07-16 Axel Wismüller , Xixi Wang , Adora M. DSouza , Mahesh B. Nagarajan

Functional Magnetic Resonance Imaging (fMRI) data is a widely used kind of four-dimensional biomedical data, which requires effective compression. However, fMRI compressing poses unique challenges due to its intricate temporal dynamics, low…

图像与视频处理 · 电气工程与系统科学 2024-03-01 Ruoran Li , Runzhao Yang , Wenxin Xiang , Yuxiao Cheng , Tingxiong Xiao , Jinli Suo

Deep neural networks dominate modern machine learning, while alternative function approximators remain comparatively underexplored at scale. In this work, we revisit kernel methods as drop-in components for standard deep learning pipelines.…

机器学习 · 计算机科学 2026-05-05 Jean-Marc Mercier , Gabriele Santin

Structural covariance analysis is a widely used structural MRI analysis method which characterises the co-relations of morphology between brain regions over a group of subjects. To our knowledge, little has been investigated in terms of the…

神经元与认知 · 定量生物学 2020-06-01 Jona Carmon , Jil Heege , Joe H Necus , Thomas W Owen , Gordon Pipa , Marcus Kaiser , Peter N Taylor , Yujiang Wang

In this paper, we investigate a divide and conquer approach to Kernel Ridge Regression (KRR). Given n samples, the division step involves separating the points based on some underlying disjoint partition of the input space (possibly via…

机器学习 · 统计学 2016-08-08 Rashish Tandon , Si Si , Pradeep Ravikumar , Inderjit Dhillon

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

Many analyses of functional magnetic resonance imaging (fMRI) examine functional connectivity (FC), or the statistical dependencies among distant brain regions. These analyses are typically exploratory, guiding future confirmatory research.…

应用统计 · 统计学 2025-10-20 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Deep learning models have shown their advantage in many different tasks, including neuroimage analysis. However, to effectively train a high-quality deep learning model, the aggregation of a significant amount of patient information is…

机器学习 · 计算机科学 2020-12-08 Xiaoxiao Li , Yufeng Gu , Nicha Dvornek , Lawrence Staib , Pamela Ventola , James S. Duncan

In this paper we propose a novel method for the segmentation of longitudinal brain MRI scans of patients suffering from Multiple Sclerosis. The method builds upon an existing cross-sectional method for simultaneous whole-brain and lesion…

图像与视频处理 · 电气工程与系统科学 2021-01-05 Stefano Cerri , Andrew Hoopes , Douglas N. Greve , Mark Mühlau , Koen Van Leemput

In this work, we describe in more detail how to perform fMRI group analysis using inputs from modeling fMRI signal using Matrix-Variate Dynamic Linear Models (MDLM) at the individual level. After computing a posterior distribution for the…

应用统计 · 统计学 2019-11-05 Johnatan Cardona Jiménez

Identifying brain regions that exhibit altered functional connectivity across cognitive or emotional states is a key problem in neuroscience. Existing methods, such as edge-wise testing, seed-based psychophysiological interaction (PPI)…

统计方法学 · 统计学 2026-02-12 Shira Yoffe , Ziv Ben-Zion , Guy Gurevitch , Talma Hendler , Malka Gorfine , Ariel Jaffe

With the progress in automatic human behavior understanding, analysing the perceived affect of multiple people has been recieved interest in affective computing community. Unlike conventional facial expression analysis, this paper primarily…

计算机视觉与模式识别 · 计算机科学 2018-09-11 Xiaohua Huang , Abhinav Dhall , Roland Goecke , Matti Pietikainen , Guoying Zhao

Background: Recent studies have indicated that functional connectivity is dynamic even during rest. A common approach to modeling the dynamic functional connectivity in whole-brain resting-state fMRI is to compute the correlation between…

神经元与认知 · 定量生物学 2019-11-05 Shih-Gu Huang , S. Balqis Samdin , Chee-Ming Ting , Hernando Ombao , Moo K. Chung

Representational Similarity Analysis (RSA) aims to explore similarities between neural activities of different stimuli. Classical RSA techniques employ the inverse of the covariance matrix to explore a linear model between the neural…

神经元与认知 · 定量生物学 2018-09-13 Xiaoliang Sheng , Muhammad Yousefnezhad , Tonglin Xu , Ning Yuan , Daoqiang Zhang

Currently there is no validated objective measure of pain. Recent neuroimaging studies have explored the feasibility of using functional near-infrared spectroscopy (fNIRS) to measure alterations in brain function in evoked and ongoing pain.…

机器学习 · 计算机科学 2018-08-22 Daniel Lopez-Martinez , Ke Peng , Sarah C. Steele , Arielle J. Lee , David Borsook , Rosalind Picard

Kernel Ridge Regression (KRR) is a simple yet powerful technique for non-parametric regression whose computation amounts to solving a linear system. This system is usually dense and highly ill-conditioned. In addition, the dimensions of the…

数值分析 · 计算机科学 2017-07-18 Haim Avron , Kenneth L. Clarkson , David P. Woodruff