相关论文: Dr-COVID: Graph Neural Networks for SARS-CoV-2 Dru…
Predicting drug-gene associations is crucial for drug development and disease treatment. While graph neural networks (GNN) have shown effectiveness in this task, they face challenges with data sparsity and efficient contrastive learning…
The Coronavirus (COVID-19), which is an infectious pulmonary disorder, has affected millions of people and has been declared as a global pandemic by the WHO. Due to highly contagious nature of COVID-19 and its high possibility of causing…
In recent years, deep learning-based image analysis methods have been widely applied in computer-aided detection, diagnosis and prognosis, and has shown its value during the public health crisis of the novel coronavirus disease 2019…
Automatic and rapid screening of COVID-19 from the chest X-ray images has become an urgent need in this pandemic situation of SARS-CoV-2 worldwide in 2020. However, accurate and reliable screening of patients is a massive challenge due to…
The pandemic of COVID-19 has caused millions of infections, which has led to a great loss all over the world, socially and economically. Due to the false-negative rate and the time-consuming of the conventional Reverse Transcription…
COVID-19 (coronavirus disease 2019) pandemic caused by SARS-CoV-2 has led to a treacherous and devastating catastrophe for humanity. At the time of writing, no specific antivirus drugs or vaccines are recommended to control infection…
The world has seen in 2020 an unprecedented global outbreak of SARS-CoV-2, a new strain of coronavirus, causing the COVID-19 pandemic, and radically changing our lives and work conditions. Many scientists are working tirelessly to find a…
Amid the coronavirus disease(COVID-19) pandemic, humanity experiences a rapid increase in infection numbers across the world. Challenge hospitals are faced with, in the fight against the virus, is the effective screening of incoming…
A pharmacological effect of a drug on cells, organs and systems refers to the specific biochemical interaction produced by a drug substance, which is called its mechanism of action. Drug repositioning (or drug repurposing) is a fundamental…
Interpreting chest radiograph, a.ka. chest x-ray, images is a necessary and crucial diagnostic tool used by medical professionals to detect and identify many diseases that may plague a patient. Although the images themselves contain a…
Background: A critical step in effective care and treatment planning for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the COVID-19 pandemic, is the assessment of the severity of disease progression. Chest…
Currently, novel coronavirus disease 2019 (COVID-19) is a big threat to global health. The rapid spread of the virus has created pandemic, and countries all over the world are struggling with a surge in COVID-19 infected cases. There are no…
The new coronavirus disease (COVID-19) has been declared a pandemic since March 2020 by the World Health Organization. It consists of an emerging viral infection with respiratory tropism that could develop atypical pneumonia. Experts…
During the first wave of COVID-19, hospitals were overwhelmed with the high number of admitted patients. An accurate prediction of the most likely individual disease progression can improve the planning of limited resources and finding the…
Objective: This study aims to consider small graphs of concepts and exploit them for expressing graph searches over existing COVID-19-related literature, leveraging the increasing use of graphs to represent and query scientific knowledge…
The novel nature of SARS-CoV-2 calls for the development of efficient de novo drug design approaches. In this study, we propose an end-to-end framework, named CogMol (Controlled Generation of Molecules), for designing new drug-like small…
In 2019, the world faced a new challenge: a COVID-19 disease caused by the novel coronavirus, SARS-CoV-2. The virus rapidly spread across the globe, leading to a high rate of mortality, which prompted health organizations to take measures…
Corona VIrus Disease abbreviated as COVID-19 is a novel virus which is initially identified in Wuhan of China in December of 2019 and now this deadly disease has spread all over the world. According to World Health Organization (WHO), a…
COVID-19 was a significant challenge that led to the loss of numerous lives daily. Not only a certain country was involved in this outbreak, but even the world has suffered because of the coronavirus. Imaging techniques using computed…
The current COVID-19 global pandemic caused by the SARS-CoV-2 betacoronavirus has resulted in over a million deaths and is having a grave socio-economic impact, hence there is an urgency to find solutions to key research challenges. Much of…