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Mild cognitive impairment (MCI) is a major public health concern due to its high risk of progressing to dementia. This study investigates the potential of detecting MCI with spontaneous voice assistant (VA) commands from 35 older adults in…

音频与语音处理 · 电气工程与系统科学 2024-11-08 Nana Lin , Youxiang Zhu , Xiaohui Liang , John A. Batsis , Caroline Summerour

Alzheimer's disease (AD) has become one of the most significant health challenges in an aging society. The use of spoken language-based AD detection methods has gained prevalence due to their scalability due to their scalability. Based on…

计算与语言 · 计算机科学 2024-12-02 Junan Li , Yunxiang Li , Yuren Wang , Xixin Wu , Helen Meng

Alzheimer's disease is a progressive neurodegenerative disorder in which mild cognitive impairment (MCI) marks a critical transition between aging and dementia. Neuroimaging modalities, such as structural MRI, provide biomarkers of this…

机器学习 · 计算机科学 2026-03-02 Vrushank Ahire , Yogesh Kumar , Anouck Girard , M. A. Ganaie

Alzheimer's disease (AD) is a degenerative brain disease impairing a person's ability to perform day to day activities. The clinical manifestations of Alzheimer's disease are characterized by heterogeneity in age, disease span, progression…

机器学习 · 计算机科学 2018-12-07 Vipul Satone , Rachneet Kaur , Faraz Faghri , Mike A Nalls , Andrew B Singleton , Roy H Campbell

Cognitive and neurological impairments are very common, but only a small proportion of affected individuals are diagnosed and treated, partly because of the high costs associated with frequent screening. Detecting pre-illness stages and…

Alzheimer's Disease is the most common cause of dementia. Accurate diagnosis and prognosis of this disease are essential to design an appropriate treatment plan, increasing the life expectancy of the patient. Intense research has been…

图像与视频处理 · 电气工程与系统科学 2023-01-05 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Objective Alzheimer disease (AD) is the most common cause of dementia, a syndrome characterized by cognitive impairment severe enough to interfere with activities of daily life. We aimed to conduct a systematic literature review (SLR) of…

定量方法 · 定量生物学 2021-08-31 Sayantan Kumar , Inez Oh , Suzanne Schindler , Albert M Lai , Philip R O Payne , Aditi Gupta

Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…

This work validates the generalizability of MRI-based classification of Alzheimer's disease (AD) patients and controls (CN) to an external data set and to the task of prediction of conversion to AD in individuals with mild cognitive…

Alzheimer's disease (AD) is a common form of dementia that severely impacts patient health. As AD impairs the patient's language understanding and expression ability, the speech of AD patients can serve as an indicator of this disease. This…

音频与语音处理 · 电气工程与系统科学 2023-07-07 Hongmin Cai , Xiaoke Huang , Zhengliang Liu , Wenxiong Liao , Haixing Dai , Zihao Wu , Dajiang Zhu , Hui Ren , Quanzheng Li , Tianming Liu , Xiang Li

Simulating dementia patients with large language models (LLMs) is challenging due to the need to jointly model cognitive impairment, emotional dynamics, and nonverbal behaviors over long conversations. We present DemMA, an expert-guided…

多智能体系统 · 计算机科学 2026-01-13 Yutong Song , Jiang Wu , Kazi Sharif , Honghui Xu , Nikil Dutt , Amir Rahmani

Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder, primarily affecting the elderly population and leading to significant cognitive decline. This decline manifests in various mental faculties such as attention,…

机器学习 · 计算机科学 2025-04-22 Emine Akpinar

Automatic detection of Alzheimer's dementia by speech processing is enhanced when features of both the acoustic waveform and the content are extracted. Audio and text transcription have been widely used in health-related tasks, as spectral…

音频与语音处理 · 电气工程与系统科学 2020-08-12 Edward L. Campbell , Laura Docío-Fernández , Javier Jiménez Raboso , Carmen García-Mateo

Alzheimer's disease is an untreatable, progressive brain disorder that slowly robs people of their memory, thinking abilities, and ultimately their capacity to complete even the most basic tasks. Among older adults, it is the most frequent…

图像与视频处理 · 电气工程与系统科学 2025-02-11 Nasser A Alsadhan

Dementia is a collection of symptoms associated with impaired cognition and impedes everyday normal functioning. Dementia, with Alzheimer's disease constituting its most common type, is highly complex in terms of etiology and…

Alzheimer's Disease (AD) is a progressive disease preceded by Mild Cognitive Impairment (MCI). Early detection of AD is crucial for making treatment decisions. However, most of the literature on computer-assisted detection of AD focuses on…

图像与视频处理 · 电气工程与系统科学 2023-09-15 Misgina Tsighe Hagos , Niamh Belton , Ronan P. Killeen , Kathleen M. Curran , Brian Mac Namee

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. Early detection of AD is crucial for effective intervention and treatment. In this paper, we propose a novel approach…

音频与语音处理 · 电气工程与系统科学 2025-04-29 Yu Pu , Wei-Qiang Zhang

Dementia is a complex syndrome impacting cognitive and emotional functions, with Alzheimer's disease being the most common form. This study focuses on enhancing dementia prediction using machine learning (ML) techniques on patient health…

人工智能 · 计算机科学 2026-01-13 Shafiul Ajam Opee , Nafiz Fahad , Anik Sen , Rasel Ahmed , Fariha Jahan , Md. Kishor Morol , Md Rashedul Islam

Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disease which destroys brain cells and causes loss to patient's memory. An early detection can prevent the patient from further damage of the brain cells and hence…

图像与视频处理 · 电气工程与系统科学 2021-01-11 Ali Nawaz , Syed Muhammad Anwar , Rehan Liaqat , Javid Iqbal , Ulas Bagci , Muhammad Majid

The early detection of Alzheimer's Disease is imperative to ensure early treatment and improve patient outcomes. There has consequently been extenstive research into detecting AD and its intermediate phase, mild cognitive impairment (MCI).…

图像与视频处理 · 电气工程与系统科学 2024-01-17 Jamie Vo , Naeha Sharif , Ghulam Mubashar Hassan