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Despite its potential for label-free particle diagnostics, holographic microscopy is limited by specialized processing methods that struggle to generalize across diverse settings. We introduce a deep learning architecture leveraging human…

光学 · 物理学 2024-11-26 Shyam Kumar , Jiarong Hong

Whole-slide image analysis via the means of computational pathology often relies on processing tessellated gigapixel images with only slide-level labels available. Applying multiple instance learning-based methods or transformer models is…

计算机视觉与模式识别 · 计算机科学 2023-10-20 Joshua Butke , Noriaki Hashimoto , Ichiro Takeuchi , Hiroaki Miyoshi , Koichi Ohshima , Jun Sakuma

Laser-assisted chemical modification is demonstrated on ultra-thin transition-metal dichalcogenides (TMDs), locally replacing selenium by sulfur atoms. The photo-conversion process takes place in a controlled reactive gas environment and…

材料科学 · 物理学 2018-08-21 Tariq Afaneh , Prasana K. Sahoo , Igor A. P. Nobrega , Yan Xin , Humberto R. Gutierrez

Metasurfaces possess the outstanding ability to tailor phase, amplitude and even spectral responses of light with an unprecedented ultrahigh resolution, thus have attracted significant interests. Here, we propose and experimentally…

Deep learning (DL) is the state-of-the-art methodology in various medical image segmentation tasks. However, it requires relatively large amounts of manually labeled training data, which may be infeasible to generate in some applications.…

图像与视频处理 · 电气工程与系统科学 2021-03-22 Long Xie , Laura E. M. Wisse , Jiancong Wang , Sadhana Ravikumar , Trevor Glenn , Anica Luther , Sydney Lim , David A. Wolk , Paul A. Yushkevich

Vision-Language Pre-training (VLP) shows remarkable progress with the assistance of extremely heavy parameters, which challenges deployment in real applications. Knowledge distillation is well recognized as the essential procedure in model…

计算机视觉与模式识别 · 计算机科学 2023-08-25 Huafeng Kuang , Jie Wu , Xiawu Zheng , Ming Li , Xuefeng Xiao , Rui Wang , Min Zheng , Rongrong Ji

Static Light Scattering (SLS) and Dynamic Light Scattering (DLS) are very important techniques to study the characteristics of nano-particles in dispersion. The data of SLS is determined by the optical characteristic and the measured values…

化学物理 · 物理学 2025-08-11 Yong Sun

Protein-based therapeutics play a pivotal role in modern medicine targeting various diseases. Despite their therapeutic importance, these products can aggregate and form subvisible particles (SvPs), which can compromise their efficacy and…

计算机视觉与模式识别 · 计算机科学 2025-01-28 Michaela Cohrs , Shiwoo Koak , Yejin Lee , Yu Jin Sung , Wesley De Neve , Hristo L. Svilenov , Utku Ozbulak

Three-dimensional ultrasound localization microscopy (ULM) enables comprehensive visualization of the vasculature, thereby improving diagnostic reliability. Nevertheless, its clinical translation remains challenging, as the exponential…

Atomically thin transition metal dichalcogenides (TMDs) have distinct opto-electronic properties including enhanced luminescence and high on-off current ratios, which can be further modulated by making more complex TMD heterostructures.…

介观与纳米尺度物理 · 物理学 2020-01-28 Akshay Singh , Hae Yeon Lee , Silvija Gradecak

We develop an integrated system of holographic optical trapping and multimodal nonlinear microscopy and perform simultaneous three-dimensional optical manipulation and non-invasive structural imaging of composite soft-matter systems. We…

软凝聚态物质 · 物理学 2015-05-20 Rahul P. Trivedi , Taewoo Lee , Kris A. Bertness , Ivan I. Smalyukh

Fluorescence imaging allows for non-invasively visualizing and measuring key physiological parameters like pH and dissolved oxygen. In our work, we created two ratiometric fluorescent microsensors designed for accurately tracking dissolved…

In this paper, the interaction of a 1064 nm continuum-wave laser with inductively-coupled plasma generated in a fluorescent light bulb has been studied both experimentally and theoretically. The absorption coefficients pertaining to the…

等离子体物理 · 物理学 2020-02-17 M. Fatih Yilmaz , M. Elif Tanriseven , Edgar Obonyo , Y. Danisman

Chalcogen-hyperdoped silicon shows potential applications in silicon-based infrared photodetectors and intermediate band solar cells. Due to the low solid solubility limits of chalcogen elements in silicon, these materials were previously…

材料科学 · 物理学 2015-03-03 S. Zhou , F. Liu , S. Prucnal , K. Gao , M. Khalid , C. Baehtz , M. Posselt , W. Skorupa , M. Helm

The state-of-the-art CMOS technology has started to adopt three-dimensional (3D) integration approaches, enabling continuous chip density increment and performance improvement, while alleviating difficulties encountered in traditional…

Particle size measurement based on digital holography with conventional algorithms are usually time-consuming and susceptible to noises associated with hologram quality and particle complexity, limiting its usage in a broad range of…

应用物理 · 物理学 2020-01-01 Siyao Shao , Kevin Mallery , Jiarong Hong

The LUX-ZEPLIN (LZ) experiment is a direct-detection dark matter experiment, optimized to search for weakly interacting massive particles (WIMPs) through WIMP-nucleon interactions. The main challenge in dark matter detection is…

仪器与探测器 · 物理学 2026-03-31 D. S. Akerib , A. K. Al Musalhi , F. Alder , B. J. Almquist , C. S. Amarasinghe , A. Ames , T. J. Anderson , N. Angelides , H. M. Araújo , J. E. Armstrong , M. Arthurs , A. Baker , S. Balashov , J. Bang , J. W. Bargemann , E. E. Barillier , K. Beattie , A. Bhatti , T. P. Biesiadzinski , H. J. Birch , E. Bishop , G. M. Blockinger , C. A. J. Brew , P. Brás , S. Burdin , M. C. Carmona-Benitez , M. Carter , A. Chawla , H. Chen , Y. T. Chin , N. I. Chott , S. Contreras , M. V. Converse , R. Coronel , A. Cottle , G. Cox , D. Curran , C. E. Dahl , I. Darlington , S. Dave , A. David , J. Delgaudio , S. Dey , L. de Viveiros , L. Di Felice , C. Ding , J. E. Y. Dobson , E. Druszkiewicz , S. Dubey , C. L. Dunbar , S. R. Eriksen , N. M. Fearon , N. Fieldhouse , S. Fiorucci , H. Flaecher , E. D. Fraser , T. M. A. Fruth , P. W. Gaemers , R. J. Gaitskell , A. Geffre , J. Genovesi , C. Ghag , J. Ghamsari , A. Ghosh , S. Ghosh , R. Gibbons , S. Gokhale , J. Green , M. G. D. van der Grinten , J. J. Haiston , C. R. Hall , T. Hall , R. H. Hampp , S. J. Haselschwardt , M. A. Hernandez , S. A. Hertel , G. J. Homenides , M. Horn , D. Q. Huang , D. Hunt , E. Jacquet , R. S. James , K. Jenkins , A. C. Kaboth , A. C. Kamaha , M. K. Kannichankandy , D. Khaitan , A. Khazov , J. Kim , Y. D. Kim , D. Kodroff , E. V. Korolkova , H. Kraus , S. Kravitz , L. Kreczko , V. A. Kudryavtsev , C. Lawes , E. B. Leon , D. S. Leonard , K. T. Lesko , C. Levy , J. Lin , A. Lindote , W. H. Lippincott , J. Long , M. I. Lopes , W. Lorenzon , C. Lu , S. Luitz , W. Ma , V. Mahajan , P. A. Majewski , A. Manalaysay , R. L. Mannino , R. J. Matheson , C. Maupin , M. E. McCarthy , D. N. McKinsey , J. McLaughlin , J. B. McLaughlin , R. McMonigle , B. Mitra , E. Mizrachi , M. E. Monzani , K. Morå , E. Morrison , B. J. Mount , M. Murdy , A. St. J. Murphy , H. N. Nelson , F. Neves , A. Nguyen , C. L. O'Brien , F. H. O'Shea , I. Olcina , K. C. Oliver-Mallory , J. Orpwood , K. Y. Oyulmaz , K. J. Palladino , N. J. Pannifer , S. J. Patton , B. Penning , G. Pereira , E. Perry , T. Pershing , A. Piepke , S. S. Poudel , Y. Qie , J. Reichenbacher , C. A. Rhyne , G. R. C. Rischbieter , E. Ritchey , H. S. Riyat , R. Rosero , N. J. Rowe , T. Rushton , D. Rynders , S. Saltão , D. Santone , A. B. M. R. Sazzad , R. W. Schnee , G. Sehr , B. Shafer , S. Shaw , W. Sherman , K. Shi , T. Shutt , C. Silva , G. Sinev , J. Siniscalco , A. M. Slivar , A. M. Softley-Brown , V. N. Solovov , P. Sorensen , J. Soria , T. J. Sumner , A. Swain , M. Szydagis , D. R. Tiedt , D. R. Tovey , J. Tranter , M. Trask , K. Trengove , M. Tripathi , A. Usón , A. C. Vaitkus , O. Valentino , V. Velan , A. Wang , J. J. Wang , Y. Wang , L. Weeldreyer , T. J. Whitis , K. Wild , M. Williams , J. Winnicki , L. Wolf , F. L. H. Wolfs , S. Woodford , D. Woodward , C. J. Wright , Q. Xia , J. Xu , Y. Xu , M. Yeh , D. Yeum , J. Young , W. Zha , H. Zhang , T. Zhang , Y. Zhou

Efficient processing of particulate products across various manufacturing steps requires that particles possess desired attributes such as size and shape. Controlling the particle production process to obtain required attributes will be…

Vision-and-language models (VLMs) have been increasingly explored in the medical domain, particularly following the success of CLIP in general domain. However, unlike the relatively straightforward pairing of 2D images and text, curating…

计算机视觉与模式识别 · 计算机科学 2025-08-19 Ziyang Zhang , Yang Yu , Xulei Yang , Si Yong Yeo

One-shot medical image segmentation faces fundamental challenges in prototype representation due to limited annotated data and significant anatomical variability across patients. Traditional prototype-based methods rely on deterministic…

计算机视觉与模式识别 · 计算机科学 2025-12-23 Ziyuan Gao , Philippe Morel
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