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The concept of autonomy is fundamental for understanding biological organization and the evolutionary transitions of living systems. Understanding how a system constitutes itself as an individual, cohesive, self-organized entity is a…

神经元与认知 · 定量生物学 2019-02-07 Miguel Aguilera , Ezequiel Di Paolo

We derive a formulation of the First Law of nonequilibrium thermodynamics for biological information-processing systems by partitioning entropy in the Second Law into microscopic and mesoscopic components and by assuming that natural…

统计力学 · 物理学 2025-11-03 Roger D. Jones , Achille Giacometti , Alan M. Jones

Sensory mechanisms in biology, from cells to humans, have the property of adaptivity, whereby the response produced by the sensor is adapted to the overall amplitude of the signal; reducing the sensitivity in the presence of strong…

生物物理 · 物理学 2017-04-26 Dan Gorbonos , Nir S. Gov

Optimal designs minimize the number of experimental runs (samples) needed to accurately estimate model parameters, resulting in algorithms that, for instance, efficiently minimize parameter estimate variance. Governed by knowledge of past…

统计方法学 · 统计学 2023-02-03 Nicholas W. Barendregt , Emily G. Webb , Zachary P. Kilpatrick

Maximum entropy estimation is of broad interest for inferring properties of systems across many different disciplines. In this work, we significantly extend a technique we previously introduced for estimating the maximum entropy of a set of…

数据分析、统计与概率 · 物理学 2016-01-05 Elliot A. Martin , Jaroslav Hlinka , Alexander Meinke , Filip Děchtěrenko , Jörn Davidsen

This paper considers multiple binary hypothesis tests with adaptive allocation of sensing resources from a shared budget over a small number of stages. A Bayesian formulation is provided for the multistage allocation problem of minimizing…

统计方法学 · 统计学 2014-11-05 Dennis Wei

The investigation of input-output systems often requires a sophisticated choice of test inputs to make best use of limited experimental time. Here we present an iterative algorithm that continuously adjusts an ensemble of test inputs…

生物物理 · 物理学 2009-11-07 Christian K. Machens

We describe the results of analytic calculations and computer simulations of adaptive predictors (predictive agents) responding to an evolving chaotic environment and to one another. Our simulations are designed to quantify adaptation and…

adap-org · 物理学 2008-02-03 Alfred Hübler , David Pines

We present a numerical method for learning unknown nonautonomous stochastic dynamical system, i.e., stochastic system subject to time dependent excitation or control signals. Our basic assumption is that the governing equations for the…

机器学习 · 计算机科学 2025-03-04 Yuan Chen , Dongbin Xiu

Biological organisms are open, adaptve systems that can respond to changes in environment in specific ways. Adaptation and response can be posed as an optimization problem, with a tradeoff between the benefit obtained from a response and…

统计力学 · 物理学 2018-10-17 Suman G. Das , Madan Rao , Garud Iyengar

High-dimensional changepoint inference that adapts to various change patterns has received much attention recently. We propose a simple, fast yet effective approach for adaptive changepoint testing. The key observation is that two…

统计方法学 · 统计学 2022-05-03 Guanghui Wang , Long Feng

Stochastic thermodynamics is formulated under the assumption of perfect knowledge of all thermodynamic parameters. However, in any real-world experiment, there is non-zero uncertainty about the precise value of temperatures, chemical…

统计力学 · 物理学 2024-01-11 Jan Korbel , David H. Wolpert

It is well known that entropy production is a proxy to the detection of non-equilibrium, i.e. of the absence of detailed balance; however, due to the global character of this quantity, its knowledge does not allow to identify spatial…

统计力学 · 物理学 2021-09-01 Camilla Sarra , Marco Baldovin , Angelo Vulpiani

The excess work required to drive a stochastic system out of thermodynamic equilibrium through a time-dependent external perturbation is directly related to the amount of entropy produced during the driving process, allowing excess work and…

统计力学 · 物理学 2021-03-15 Steven J Large , Jannik Ehrich , David A Sivak

We derive statistical-mechanical speed limits on dissipation from the classical, chaotic dynamics of many-particle systems. In one, the rate of irreversible entropy production in the environment is the maximum speed of a deterministic…

统计力学 · 物理学 2024-06-19 Swetamber Das , Jason R. Green

The climate system is a forced, dissipative, nonlinear, complex and heterogeneous system that is out of thermodynamic equilibrium. The system exhibits natural variability on many scales of motion, in time as well as space, and it is subject…

大气与海洋物理 · 物理学 2020-08-05 Michael Ghil , Valerio Lucarini

Biological systems (among others) may respond to a large variety of distinct external stimuli, or signals. These perturbations will generally be presented to the system not singly, but in various combinations, so that a proper understanding…

定量方法 · 定量生物学 2011-06-24 Dennis Wylie

Sensing is the process of deriving signals from the environment that allows artificial systems to interact with the physical world. The Shannon theorem specifies the maximum rate at which information can be acquired. However, this upper…

神经与进化计算 · 计算机科学 2018-02-16 Anh Tuan Nguyen , Jian Xu , Zhi Yang

Transmission of real-time data is strongly increasing due to remote processing of sensor data, among other things. A route to meet this demand is adaptive sensing, in which sensors acquire only relevant information using pre-processing at…

应用物理 · 物理学 2020-07-15 Claudia Lenk , Lars Seeber , Martin Ziegler , Philipp Hövel , Stefanie Gutschmidt

We develop the stochastic approach to thermodynamics based on the stochastic dynamics, which can be discrete (master equation) continuous (Fokker-Planck equation), and on two assumptions concerning entropy. The first is the definition of…

统计力学 · 物理学 2015-06-11 Tânia Tomé , Mário J. de Oliveira