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We focus on the problem of generalizing a causal effect estimated on a randomized controlled trial (RCT) to a target population described by a set of covariates from observational data. Available methods such as inverse propensity sampling…

统计方法学 · 统计学 2023-02-27 Imke Mayer , Julie Josse , Traumabase Group

Breast cancer is one of the most threatening diseases in women's life; thus, the early and accurate diagnosis plays a key role in reducing the risk of death in a patient's life. Mammography stands as the reference technique for breast…

机器学习 · 计算机科学 2023-05-05 Juan Zuluaga-Gomez

When treatment policy estimands are of interest, clinical trials often attempt to collect patient data after intercurrent events (ICEs), although such data are often limited. Retrieved dropout imputation methods, which use pre-ICE and…

统计方法学 · 统计学 2026-03-31 Brendah Nansereko , Marcel Wolbers , James R. Carpenter , Jonathan W. Bartlett

The estimation of missing input vector elements in real time processing applications requires a system that possesses the knowledge of certain characteristics such as correlations between variables, which are inherent in the input space.…

应用统计 · 统计学 2007-05-23 Fulufhelo V. Nelwamondo , Shakir Mohamed , Tshilidzi Marwala

Environmental, Social, and Governance (ESG) datasets are frequently plagued by significant data gaps, leading to inconsistencies in ESG ratings due to varying imputation methods. This paper explores the application of established machine…

机器学习 · 计算机科学 2024-07-30 Sergio Caprioli , Jacopo Foschi , Riccardo Crupi , Alessandro Sabatino

Many data mining and data analysis techniques operate on dense matrices or complete tables of data. Real-world data sets, however, often contain unknown values. Even many classification algorithms that are designed to operate with missing…

神经与进化计算 · 计算机科学 2013-12-20 Michael S. Gashler , Michael R. Smith , Richard Morris , Tony Martinez

Missing data is a common problem in real-world settings and particularly relevant in healthcare applications where researchers use Electronic Health Records (EHR) and results of observational studies to apply analytics methods. This issue…

机器学习 · 统计学 2018-12-04 Dimitris Bertsimas , Agni Orfanoudaki , Colin Pawlowski

In clinical trials, mixed effects models for repeated measures (MMRM) and pattern mixture models (PMM) are often used to analyze longitudinal continuous outcomes. We describe a simple missing data imputation algorithm for the MMRM that can…

统计方法学 · 统计学 2016-10-13 Yongqiang Tang

Handling missing values in training datasets for constructing learning models or extracting useful information is considered to be an important research task in data mining and knowledge discovery in databases. In recent years, lot of…

数据库 · 计算机科学 2009-04-22 Shariq Bashir , Saad Razzaq , Umer Maqbool , Sonya Tahir , Abdul Rauf Baig

Missing data is a pervasive issue in statistical analyses, affecting the reliability and validity of research across diverse scientific disciplines. Failure to adequately address missing data can lead to biased estimates and consequently…

统计方法学 · 统计学 2025-05-06 Asmaa Ahmad , Eric J Rose , Michael Roy , Edward Valachovic

Missing data are inevitable in longitudinal studies. Traditional methods, such as the full information maximum likelihood (FIML), are commonly used to handle ignorable missing data. However, they may lead to biased model estimation due to…

应用统计 · 统计学 2024-01-01 Dandan Tang , Xin Tong

Multiple imputation provides an effective way to handle missing data. When several possible models are under consideration for the data, the multiple imputation is typically performed under a single-best model selected from the candidate…

统计方法学 · 统计学 2018-11-30 Gyuhyeong Goh , Jae Kwang Kim

We study the problem of imputing missing values in a dataset, which has important applications in many domains. The key to missing value imputation is to capture the data distribution with incomplete samples and impute the missing values…

机器学习 · 计算机科学 2023-06-26 He Zhao , Ke Sun , Amir Dezfouli , Edwin Bonilla

Due to complex experimental settings, missing values are common in biomedical data. To handle this issue, many methods have been proposed, from ignoring incomplete instances to various data imputation approaches. With the recent rise of…

机器学习 · 计算机科学 2020-05-14 Kristian Miok , Dong Nguyen-Doan , Marko Robnik-Šikonja , Daniela Zaharie

Missing data is a common problem faced with real-world datasets. Imputation is a widely used technique to estimate the missing data. State-of-the-art imputation approaches, such as Generative Adversarial Imputation Nets (GAIN), model the…

机器学习 · 计算机科学 2020-12-02 Saqib Ejaz Awan , Mohammed Bennamoun , Ferdous Sohel , Frank M Sanfilippo , Girish Dwivedi

Healthcare time series data is vital for monitoring patient activity but often contains noise and missing values due to various reasons such as sensor errors or data interruptions. Imputation, i.e., filling in the missing values, is a…

机器学习 · 计算机科学 2024-12-17 Lien P. Le , Xuan-Hien Nguyen Thi , Thu Nguyen , Michael A. Riegler , Pål Halvorsen , Binh T. Nguyen

The ICH E9(R1) Addendum (International Council for Harmonization 2019) suggests treatment-policy as one of several strategies for addressing intercurrent events such as treatment withdrawal when defining an estimand. This strategy requires…

统计方法学 · 统计学 2023-08-28 Suzie Cro , James H Roger , James R Carpenter

There has been an increasing interest in using cell and gene therapy (CGT) to treat/cure difficult diseases. The hallmark of CGT trials are the small sample size and extremely high efficacy. Due to the innovation and novelty of such…

应用统计 · 统计学 2025-10-23 Yaoyuan Vincent Tan , Gang Xu , Chenkun Wang

Missing data is a common problem in practical data science settings. Various imputation methods have been developed to deal with missing data. However, even though the labels are available in the training data in many situations, the common…

机器学习 · 计算机科学 2025-01-30 Thu Nguyen , Tuan L. Vo , Pål Halvorsen , Michael A. Riegler

In the last couple of decades, there has been major advancements in the domain of missing data imputation. The techniques in the domain include amongst others: Expectation Maximization, Neural Networks with Evolutionary Algorithms or…

神经与进化计算 · 计算机科学 2015-12-07 Collins Leke , Tshilidzi Marwala , Satyakama Paul