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Most modern imaging systems incorporate a computational pipeline to infer the image of interest from acquired measurements. The Bayesian approach to solve such ill-posed inverse problems involves the characterization of the posterior…

计算机视觉与模式识别 · 计算机科学 2023-05-26 Pakshal Bohra , Thanh-an Pham , Jonathan Dong , Michael Unser

Segmentation of structural and diffusion MRI (sMRI/dMRI) is usually performed independently in neuroimaging pipelines. However, some brain structures (e.g., globus pallidus, thalamus and its nuclei) can be extracted more accurately by…

计算机视觉与模式识别 · 计算机科学 2019-03-12 Juan Eugenio Iglesias , Koen Van Leemput , Polina Golland , Anastasia Yendiki

Motivation. Understanding the pan-cancer mutational landscape offers critical insights into the molecular mechanisms underlying tumorigenesis. While patient-level machine learning techniques have been widely employed to identify tumor…

机器学习 · 计算机科学 2025-08-29 Yifan Dou , Adam Khadre , Ruben C Petreaca , Golrokh Mirzaei

In this work, we propose a new Bayesian spatial homogeneity pursuit method for survival data under the proportional hazards model to detect spatially clustered patterns in baseline hazard and regression coefficients. Specially, regression…

应用统计 · 统计学 2021-02-24 Lijiang Geng , Guanyu Hu

This paper aims to improve the accuracy of texture classification based on extracting texture features using five different texture methods and classifying the patterns using a naive Bayesian classifier. Three statistical-based and two…

计算机视觉与模式识别 · 计算机科学 2015-12-31 Omar Al-Kadi

Integrative network modeling of data arising from multiple genomic platforms provides insight into the holistic picture of the interactive system, as well as the flow of information across many disease domains including cancer. The basic…

统计方法学 · 统计学 2020-02-18 Min Jin Ha , Francesco Stingo , Veerabhadran Baladandayuthapani

Motivation. Cancer heterogeneity is observed at multiple biological levels. To improve our understanding of these differences and their relevance in medicine, approaches to link organ- and tissue-level information from diagnostic images and…

定量方法 · 定量生物学 2020-05-19 Nova F. Smedley , Suzie El-Saden , William Hsu

Prediction of survivability in a patient for tumor progression is useful to estimate the effectiveness of a treatment protocol. In our work, we present a model to take into account the heterogeneous nature of a tumor to predict survival.…

We introduce a Bayesian nonparametric regression model for data with multiway (tensor) structure, motivated by an application to periodontal disease (PD) data. Our outcome is the number of diseased sites measured over four different tooth…

应用统计 · 统计学 2019-02-01 Eric F. Lock , Dipankar Bandyopadhyay

This paper presents an unsupervised Bayesian algorithm for hyperspectral image unmixing accounting for endmember variability. The pixels are modeled by a linear combination of endmembers weighted by their corresponding abundances. However,…

统计方法学 · 统计学 2015-10-28 Abderrahim Halimi , Nicolas Dobigeon , Jean-Yves Tourneret

In many real life problems, objects are described by large number of binary features. For instance, documents are characterized by presence or absence of certain keywords; cancer patients are characterized by presence or absence of certain…

应用统计 · 统计学 2016-03-09 Tapesh Santra

We propose a Bayesian approach for model-based clustering of multivariate categorical data where variables are allowed to be associated within clusters and the number of clusters is unknown. The approach uses a two-layer mixture of finite…

统计方法学 · 统计学 2024-07-09 Gertraud Malsiner-Walli , Bettina Grün , Sylvia Frühwirth-Schnatter

Super-resolution imaging techniques have largely improved our capabilities to visualize nanometric structures in biological systems. Their application further enables one to potentially quantitate relevant parameters to determine the…

生物物理 · 物理学 2019-12-18 Tina Kosǔta , Marta Cullell-Dalmau , Francesca Cella Zanacchi , Carlo Manzo

Data scarcity hinders deep learning for medical imaging. We propose a framework for breast cancer classification in thermograms that addresses this using a Diffusion Probabilistic Model (DPM) for data augmentation. Our DPM-based…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Sepehr Salem , M. Moein Esfahani , Jingyu Liu , Vince Calhoun

Deep learning models, such as convolutional neural networks, have long been applied to image and multi-media tasks, particularly those with structured data. More recently, there has been more attention to unstructured data that can be…

机器学习 · 计算机科学 2021-09-17 Rohitash Chandra , Ayush Bhagat , Manavendra Maharana , Pavel N. Krivitsky

We present a nonparametric Bayesian method for disease subtype discovery in multi-dimensional cancer data. Our method can simultaneously analyse a wide range of data types, allowing for both agreement and disagreement between their…

基因组学 · 定量生物学 2013-04-16 Richard S. Savage , Zoubin Ghahramani , Jim E. Griffin , Paul Kirk , David L. Wild

Graph convolutional neural networks (GCNN) have been successfully applied to many different graph based learning tasks including node and graph classification, matrix completion, and learning of node embeddings. Despite their impressive…

机器学习 · 计算机科学 2019-10-29 Soumyasundar Pal , Florence Regol , Mark Coates

The characterization of Tumor MicroEnvironment (TME) is challenging due to its complexity and heterogeneity. Relatively consistent TME characteristics embedded within highly specific tissue features, render them difficult to predict. The…

计算机视觉与模式识别 · 计算机科学 2024-07-09 Fangliangzi Meng , Hongrun Zhang , Ruodan Yan , Guohui Chuai , Chao Li , Qi Liu

Development of resistance limits efficiency of present anticancer therapies and preventing it remains big challenge in cancer research. It is accepted, at intuitive level, that the resistance emerges as a consequence of cancer cells…

定量方法 · 定量生物学 2015-06-02 Branislav Brutovsky , Denis Horvath

It is very challenging to select informative features from tens of thousands of measured features in high-throughput data analysis. Recently, several parametric/regression models have been developed utilizing the gene network information to…

应用统计 · 统计学 2014-08-01 Yize Zhao , Jian Kang , Tianwei Yu