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As medical diagnoses increasingly leverage multimodal data, machine learning models are expected to effectively fuse heterogeneous information while remaining robust to missing modalities. In this work, we propose a novel multimodal…

计算机视觉与模式识别 · 计算机科学 2025-09-24 Yi Gu , Kuniaki Saito , Jiaxin Ma

There is a rising need for computational models that can complementarily leverage data of different modalities while investigating associations between subjects for population-based disease analysis. Despite the success of convolutional…

图像与视频处理 · 电气工程与系统科学 2020-09-08 Yongxiang Huang , Albert C. S. Chung

Background: AI-driven prediction algorithms have the potential to enhance emergency medicine by enabling rapid and accurate decision-making regarding patient status and potential deterioration. However, the integration of multimodal data,…

机器学习 · 计算机科学 2025-05-02 Juan Miguel Lopez Alcaraz , Hjalmar Bouma , Nils Strodthoff

The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…

图像与视频处理 · 电气工程与系统科学 2019-07-16 Kilian Hett , Vinh-Thong Ta , José V. Manjón , Pierrick Coupé

Algorithmic image-based diagnosis and prognosis of neurodegenerative diseases on longitudinal data has drawn great interest from computer vision researchers. The current state-of-the-art models for many image classification tasks are based…

计算机视觉与模式识别 · 计算机科学 2017-09-04 Jie Zhang , Qingyang Li , Richard J. Caselli , Jieping Ye , Yalin Wang

Accurate extraction of molecular representations is a critical step in the drug discovery process. In recent years, significant progress has been made in molecular representation learning methods, among which multi-modal molecular…

机器学习 · 计算机科学 2025-05-13 Rong Yin , Ruyue Liu , Xiaoshuai Hao , Xingrui Zhou , Yong Liu , Can Ma , Weiping Wang

In order to find effective treatments for Alzheimer's disease (AD), we need to identify subjects at risk of AD as early as possible. To this end, recently developed disease progression models can be used to perform early diagnosis, as well…

定量方法 · 定量生物学 2020-03-11 Razvan V. Marinescu

The Lewy body dementia (LBD) is the second most common neurodegenerative dementia after Alzheimer's disease (AD). Early differentiation between AD and LBD is crucial because they require different treatment approaches, but this is…

机器学习 · 计算机科学 2025-03-12 Jing Zhang , Xiaowei Yu , Tong Chen , Chao Cao , Mingheng Chen , Yan Zhuang , Yanjun Lyu , Lu Zhang , Li Su , Tianming Liu , Dajiang Zhu

Pre-symptomatic (or Preclinical) Alzheimer's Disease is defined by biomarker evidence of fibrillar amyloid beta pathology in the absence of clinical symptoms. Clinical trials in this early phase of disease are challenging due to the slow…

应用统计 · 统计学 2020-03-10 Dan Li , Samuel Iddi , Paul S. Aisen , Wesley K. Thompson , Michael C. Donohue

The application of machine learning in medicine and healthcare has led to the creation of numerous diagnostic and prognostic models. However, despite their success, current approaches generally issue predictions using data from a single…

机器学习 · 计算机科学 2025-05-13 Fergus Imrie , Stefan Denner , Lucas S. Brunschwig , Klaus Maier-Hein , Mihaela van der Schaar

Deep neural networks are increasingly being used for the analysis of medical images. However, most works neglect the uncertainty in the model's prediction. We propose an uncertainty-aware deep kernel learning model which permits the…

机器学习 · 计算机科学 2021-06-11 Zhiliang Wu , Yinchong Yang , Jindong Gu , Volker Tresp

Accurate compensation of brain deformation is a critical challenge for reliable image-guided neurosurgery, as surgical manipulation and tumor resection induce tissue motion that misaligns preoperative planning images with intraoperative…

This paper presents a novel deep learning-based approach named RealDiffFusionNet incorporating Neural Controlled Differential Equations (Neural CDE) - time series models that are robust in handling irregularly sampled data - and multi-head…

机器学习 · 计算机科学 2025-01-07 Aashish Cheruvu , Nathaniel Rigoni

Chronic wounds affect 8.5 million Americans, particularly the elderly and patients with diabetes. These wounds can take up to nine months to heal, making regular care essential to ensure healing and prevent severe outcomes like limb…

Machine learning has been increasingly used to obtain individualized neuroimaging signatures for disease diagnosis, prognosis, and response to treatment in neuropsychiatric and neurodegenerative disorders. Therefore, it has contributed to a…

This study evaluates a multimodal machine learning framework for predicting treatment outcomes in intracranial aneurysms (IAs). Combining angiographic parametric imaging (API), patient biomarkers, and disease morphology, the framework aims…

Multimodal learning, especially large-scale multimodal pre-training, has developed rapidly over the past few years and led to the greatest advances in artificial intelligence (AI). Despite its effectiveness, understanding the underlying…

神经与进化计算 · 计算机科学 2022-08-18 Haoyu Lu , Qiongyi Zhou , Nanyi Fei , Zhiwu Lu , Mingyu Ding , Jingyuan Wen , Changde Du , Xin Zhao , Hao Sun , Huiguang He , Ji-Rong Wen

Alzheimer's disease affects over 55 million people worldwide and is projected to more than double by 2050, necessitating rapid, accurate, and scalable diagnostics. However, existing approaches are limited because they cannot achieve…

计算机视觉与模式识别 · 计算机科学 2025-07-29 Ahmed Sharshar , Yasser Ashraf , Tameem Bakr , Salma Hassan , Hosam Elgendy , Mohammad Yaqub , Mohsen Guizani

Alzheimer's disease (AD) is an irreversible devastative neurodegenerative disorder associated with progressive impairment of memory and cognitive functions. Its early diagnosis is crucial for the development of possible future treatment…

计算机视觉与模式识别 · 计算机科学 2020-04-07 Ahsan Bin Tufail , Qiu-Na Zhang , Yong-Kui Ma

Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent…

图像与视频处理 · 电气工程与系统科学 2022-02-07 Saman Sotoudeh-Paima , Ata Jodeiri , Fedra Hajizadeh , Hamid Soltanian-Zadeh
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