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Cell Painting is a microscopy-based, high-content imaging assay that produces rich morphological profiles of cells and can support drug discovery by quantifying cellular responses to chemical perturbations. At scale, however, Cell Painting…

机器学习 · 计算机科学 2026-02-02 Aditya Narayan Ravi , Snehal Vadvalkar , Abhishek Pandey , Ilan Shomorony

Aberration correction is an important aspect of modern high-resolution scanning transmission electron microscopy. Most methods of aligning aberration correctors require specialized sample regions and are unsuitable for fine-tuning…

Nonparametric estimation using uniform-width binning is a standard approach for evaluating the calibration performance of machine learning models. However, existing theoretical analyses of the bias induced by binning are limited to binary…

机器学习 · 计算机科学 2025-07-14 Masahiro Fujisawa , Futoshi Futami

Convolutional Neural Networks (CNN) have had a huge success in many areas of computer vision and medical image analysis. However, there is still an immense potential for performance improvement in mammogram breast cancer detection…

计算机视觉与模式识别 · 计算机科学 2018-08-28 Yeman Brhane Hagos , Albert Gubern Merida , Jonas Teuwen

Bayesian Neural Networks (BNNs) provide principled estimates of model and data uncertainty by encoding parameters as distributions. This makes them key enablers for reliable AI that can be deployed on safety critical edge systems. These…

新兴技术 · 计算机科学 2024-11-13 Prabodh Katti , Bashir M. Al-Hashimi , Bipin Rajendran

Comparative diagnostic in brain tumor evaluation makes possible to use the available information of a medical center to compare similar cases when a new patient is evaluated. By leveraging Artificial Intelligence models, the proposed system…

图像与视频处理 · 电气工程与系统科学 2024-05-31 Guillermo Iglesias , Edgar Talavera , Jesús Troya Garcìa , Alberto Díaz-Álvarez , Miguel Gracía-Remesal

This study investigates the application of Bayesian Optimization (BO) for the hyperparameter tuning of neural networks, specifically targeting the enhancement of Convolutional Neural Networks (CNN) for image classification tasks. Bayesian…

机器学习 · 计算机科学 2024-10-30 Gabriele Onorato

Approximate Bayesian Computation is widely used in systems biology for inferring parameters in stochastic gene regulatory network models. Its performance hinges critically on the ability to summarize high-dimensional system responses such…

机器学习 · 统计学 2021-04-13 Mattias Åkesson , Prashant Singh , Fredrik Wrede , Andreas Hellander

Estimated uncertainty by approximate posteriors in Bayesian neural networks are prone to miscalibration, which leads to overconfident predictions in critical tasks that have a clear asymmetric cost or significant losses. Here, we extend the…

机器学习 · 计算机科学 2022-06-17 Biraja Ghoshal , Allan Tucker

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

图像与视频处理 · 电气工程与系统科学 2022-01-14 Jiaqiao Shi , Aleksandar Vakanski , Min Xian , Jianrui Ding , Chunping Ning

Conventional model quantization methods use a fixed quantization scheme to different data samples, which ignores the inherent "recognition difficulty" differences between various samples. We propose to feed different data samples with…

计算机视觉与模式识别 · 计算机科学 2022-04-22 Chen Tang , Haoyu Zhai , Kai Ouyang , Zhi Wang , Yifei Zhu , Wenwu Zhu

The mean field variational Bayes (VB) algorithm implemented in Stan is relatively fast and efficient, making it feasible to produce model-estimated official statistics on a rapid timeline. Yet, while consistent point estimates of parameters…

统计方法学 · 统计学 2024-07-08 Terrance D. Savitsky , Julie Gershunskaya

We propose a new class of Bayesian neural networks (BNNs) that can be trained using noisy data of variable fidelity, and we apply them to learn function approximations as well as to solve inverse problems based on partial differential…

机器学习 · 计算机科学 2021-06-02 Xuhui Meng , Hessam Babaee , George Em Karniadakis

Multi-gene panel testing allows efficient detection of pathogenic variants in cancer susceptibility genes including moderate-risk genes such as ATM and PALB2. A growing number of studies examine the risk of breast cancer (BC) conferred by…

统计方法学 · 统计学 2024-02-26 Thanthirige Lakshika M. Ruberu , Danielle Braun , Giovanni Parmigiani , Swati Biswas

Quantum machine learning promises great speedups over classical algorithms, but it often requires repeated computations to achieve a desired level of accuracy for its point estimates. Bayesian learning focuses more on sampling from…

量子物理 · 物理学 2021-07-21 Noah Berner , Vincent Fortuin , Jonas Landman

Bayesian adaptive designs enable flexible clinical trials by adapting features based on accumulating data. Among these, Bayesian Response-Adaptive Randomization (BRAR) skews patient allocation towards more promising treatments based on…

统计方法学 · 统计学 2025-12-05 Daniel Kaddaj , Stef Baas , Edwin Y. N. Tang , David S. Robertson , Lukas Pin , Sofía S. Villar

Bayesian Neural Networks (BNNs) provide a tool to estimate the uncertainty of a neural network by considering a distribution over weights and sampling different models for each input. In this paper, we propose a method for uncertainty…

机器学习 · 计算机科学 2024-10-28 Illia Oleksiienko , Dat Thanh Tran , Alexandros Iosifidis

We study methods for reconstructing Bayesian uncertainties on dynamical mass estimates of galaxy clusters using convolutional neural networks (CNNs). We discuss the statistical background of approximate Bayesian neural networks and…

宇宙学与河外天体物理 · 物理学 2021-03-16 Matthew Ho , Arya Farahi , Markus Michael Rau , Hy Trac

Accurate identification of breast cancer types plays a critical role in guiding treatment decisions and improving patient outcomes. This paper presents an artificial intelligence enabled tool designed to aid in the identification of breast…

图像与视频处理 · 电气工程与系统科学 2025-05-28 Neil Chaudhary , Zaynah Dhunny

Achieving maximum scientific results from the overwhelming volume of astronomical data to be acquired over the next few decades will demand novel, fully automatic methods of data analysis. Artificial intelligence approaches hold great…