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The increasing deployment of artificial intelligence (AI) in clinical settings challenges foundational assumptions underlying traditional frameworks of medical evidence. Classical statistical approaches, centered on randomized controlled…

统计方法学 · 统计学 2026-01-07 Richik Chakraborty

Multimodal large language models (MLLMs) have emerged as powerful tools for computational pathology, offering unprecedented opportunities to integrate pathological images with language context for comprehensive diagnostic analysis. These…

Clinical decision support tools rooted in machine learning and optimization can provide significant value to healthcare providers, including through better management of intensive care units. In particular, it is important that the patient…

机器学习 · 计算机科学 2021-12-20 Fernando Lejarza , Jacob Calvert , Misty M Attwood , Daniel Evans , Qingqing Mao

A treatment policy defines when and what treatments are applied to affect some outcome of interest. Data-driven decision-making requires the ability to predict what happens if a policy is changed. Existing methods that predict how the…

机器学习 · 计算机科学 2023-06-21 Çağlar Hızlı , ST John , Anne Juuti , Tuure Saarinen , Kirsi Pietiläinen , Pekka Marttinen

Traffic prediction is pivotal for rational transportation supply scheduling and allocation. Existing researches into short-term traffic prediction, however, face challenges in adequately addressing exceptional circumstances and integrating…

计算与语言 · 计算机科学 2024-05-14 Xiannan Huang

Current clinical decision support systems (CDSSs) typically base their predictions on correlation, not causation. In recent years, causal machine learning (ML) has emerged as a promising way to improve decision-making with CDSSs by offering…

人机交互 · 计算机科学 2026-04-17 Domenique Zipperling , Lukas Schmidt , Benedikt Hahn , Niklas Kühl , Steven Kimbrough

Deep-learning-based clinical decision support using structured electronic health records (EHR) has been an active research area for predicting risks of mortality and diseases. Meanwhile, large amounts of narrative clinical notes provide…

计算与语言 · 计算机科学 2023-05-10 Weimin Lyu , Xinyu Dong , Rachel Wong , Songzhu Zheng , Kayley Abell-Hart , Fusheng Wang , Chao Chen

Many diseases, including cancer and chronic conditions, require extended treatment periods and long-term strategies. Machine learning and AI research focusing on electronic health records (EHRs) have emerged to address this need. Effective…

Artificial intelligence, and particularly machine learning (ML), is increasingly developed and deployed to support healthcare in a variety of settings. However, clinical decision support (CDS) technologies based on ML need to be portable if…

机器学习 · 计算机科学 2022-07-07 Steve Nyemba , Chao Yan , Ziqi Zhang , Amol Rajmane , Pablo Meyer , Prithwish Chakraborty , Bradley Malin

Data mining and machine learning hold great potential to enable health systems to systematically use data and analytics to identify inefficiencies and best practices that improve care and reduce costs. Waveform data offers particularly…

机器学习 · 计算机科学 2025-03-17 Michael Albada

Clinical prediction models are statistical or machine learning models used to quantify the risk of a certain health outcome using patient data. These can then inform potential interventions on patients, causing an effect called performative…

机器学习 · 计算机科学 2024-06-06 Louis Chislett , Louis JM Aslett , Alisha R Davies , Catalina A Vallejos , James Liley

Much work aims to explain a model's prediction on a static input. We consider explanations in a temporal setting where a stateful dynamical model produces a sequence of risk estimates given an input at each time step. When the estimated…

Large Language Models (LLMs) have emerged as powerful candidates to inform clinical decision-making processes. While these models play an increasingly prominent role in shaping the digital landscape, two growing concerns emerge in…

计算与语言 · 计算机科学 2024-04-24 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

We introduce PRISM (Predictive Reasoning in Sequential Medicine), a transformer-based architecture designed to model the sequential progression of clinical decision-making processes. Unlike traditional approaches that rely on isolated…

计算与语言 · 计算机科学 2025-06-16 Lionel Levine , John Santerre , Alex S. Young , T. Barry Levine , Francis Campion , Majid Sarrafzadeh

Background: Advanced adaptive randomised clinical trials are increasingly used. Compared to their conventional counterparts, their flexibility may make them more efficient, increase the probability of obtaining conclusive results without…

Medical AI, including clinical language models, vision-language models, and multimodal health record models, already summarizes notes, answers questions, and supports decisions. Their adaptation to new populations, specialties, or care…

The emergence of agentic Artificial Intelligence (AI), which can operate autonomously, demonstrate goal-directed behavior, and adaptively learn, indicates the onset of a massive change in today's computing infrastructure. This study…

新兴技术 · 计算机科学 2025-09-23 Nauman Ali Murad , Safia Baloch

There is a need of ensuring machine learning models that are interpretable. Higher interpretability of the model means easier comprehension and explanation of future predictions for end-users. Further, interpretable machine learning models…

机器学习 · 计算机科学 2020-08-17 Gregor Stiglic , Primoz Kocbek , Nino Fijacko , Marinka Zitnik , Katrien Verbert , Leona Cilar

Clinical decision support tools built on electronic health records often experience performance drift due to temporal population shifts, particularly when changes in the clinical environment initially affect only a subset of patients,…

机器学习 · 计算机科学 2025-12-16 Mengying Yan , Ziye Tian , Siqi Li , Nan Liu , Benjamin A. Goldstein , Molei Liu , Chuan Hong

Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is…

机器学习 · 统计学 2016-08-17 Joseph Futoma , Mark Sendak , C. Blake Cameron , Katherine Heller