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Online searches have been used to study different health-related behaviours, including monitoring disease outbreaks. An obvious caveat is that several reasons can motivate individuals to seek online information and models that are blind to…

机器学习 · 计算机科学 2021-01-19 Sara Mesquita , Cláudio Haupt Vieira , Lília Perfeito , Joana Gonçalves-Sá

We review research papers which use game theory to model the decision making of individuals during an epidemic, attempting to classify the literature and identify the emerging trends in this field. We show that the literature can be…

种群与进化 · 定量生物学 2020-02-13 Sheryl L. Chang , Mahendra Piraveenan , Philippa Pattison , Mikhail Prokopenko

We consider the batch (off-line) policy learning problem in the infinite horizon Markov Decision Process. Motivated by mobile health applications, we focus on learning a policy that maximizes the long-term average reward. We propose a…

统计理论 · 数学 2022-09-20 Peng Liao , Zhengling Qi , Runzhe Wan , Predrag Klasnja , Susan Murphy

In this paper, we study the optimal control for an SEIR model adapted to the vaccination strategy of susceptible individuals. There are factors associated with a vaccination campaign that make this strategy not only a public health issue…

最优化与控制 · 数学 2024-11-08 Nelson L. Santos Junior , João A. M. Gondim

Given multiple new COVID-19 variants are continuously emerging, non-pharmaceutical interventions are still primary control strategies to curb the further spread of coronavirus. However, implementing strict interventions over extended…

种群与进化 · 定量生物学 2022-03-01 Xiao Zhou , Xiaohu Zhang , Paolo Santi , Carlo Ratti

Metapopulation epidemic models help capture the spatial dimension of infectious disease spread by dividing heterogeneous populations into separate but interconnected communities, represented by nodes in a network. In the event of an…

种群与进化 · 定量生物学 2025-02-21 Henrik Zunker , Philipp Dönges , Patrick Lenz , Seba Contreras , Martin J. Kühn

In the wake of COVID-19, every government huddles to find the best interventions that will reduce the number of infection cases while minimizing the economic impact. However, with many intervention policies available, how should one decide…

最优化与控制 · 数学 2021-04-19 Chang Liu , Akshay Budhkar

The widespread, and in many countries unprecedented, use of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic has highlighted the need for mathematical models which can estimate the impact of these measures while…

Influence maximization is the problem of finding a set of users in a social network, such that by targeting this set, one maximizes the expected spread of influence in the network. Most of the literature on this topic has focused…

数据库 · 计算机科学 2011-10-03 Amit Goyal , Francesco Bonchi , Laks V. S. Lakshmanan

The exploration of epidemic dynamics on dynamically evolving ("adaptive") networks poses nontrivial challenges to the modeler, such as the determination of a small number of informative statistics of the detailed network state (that is, a…

定量方法 · 定量生物学 2015-07-07 Assimakis A. Kattis , Alexander Holiday , Ana-Andreea Stoica , Ioannis G. Kevrekidis

Model predictive control (MPC) provides a useful means for controlling systems with constraints, but suffers from the computational burden of repeatedly solving an optimization problem in real time. Offline (explicit) solutions for MPC…

系统与控制 · 电气工程与系统科学 2022-09-14 Daniel Tabas , Baosen Zhang

Epidemic spread in a population is traditionally modeled via compartmentalized models which represent the free evolution of disease in absence of any intervention policies. In addition, these models assume full observability of disease…

种群与进化 · 定量生物学 2021-06-16 Nitin Kamra , Yizhou Zhang , Sirisha Rambhatla , Chuizheng Meng , Yan Liu

In this work we analyze mathematically the consequences and effectiveness of strategies to control an epidemic in the framework of classical SEIR models with multiple parallel infectious stages. We define the mathematical concept of a…

动力系统 · 数学 2023-08-17 Annibal Figueiredo , Tarcısio Marciano da Rocha Filho

In randomized trials involving multiple treatments, bivariate survival outcomes present significant analytical challenges for making decisions. This paper addresses the problem of deriving optimal individualized treatment rules to maximize…

机器学习 · 统计学 2026-05-29 Kun Ren , Yifan Cui , Wen Su

We demonstrate an approach to replicate and forecast the spread of the SARS-CoV-2 (COVID-19) pandemic using the toolkit of probabilistic programming languages (PPLs). Our goal is to study the impact of various modeling assumptions and…

机器学习 · 统计学 2022-03-08 Swapneel Mehta , Noah Kasmanoff

Suppose an online platform wants to compare a treatment and control policy, e.g., two different matching algorithms in a ridesharing system, or two different inventory management algorithms in an online retail site. Standard randomized…

统计方法学 · 统计学 2022-12-27 Peter Glynn , Ramesh Johari , Mohammad Rasouli

Epidemics expose critical tensions between protecting public health and maintaining essential urban mobility. Public transport systems face this dilemma most acutely: they enable access to jobs, education, and services, yet also facilitate…

物理与社会 · 物理学 2025-11-11 Gerhard Hiermann , Joana Ji , Ana Moreno , Rolf Moeckel , Maximilian Schiffer

During pandemic events, strategies such as social distancing can be fundamental to curb viral spreading. Such actions can reduce the number of simultaneous infections and mitigate the disease spreading, which is relevant to the risk of a…

物理与社会 · 物理学 2021-02-24 Marco A. Amaral , Marcelo M. de Oliveira , Marco A. Javarone

The appearance of a new dangerous and contagious disease requires the development of a drug therapy faster than what is foreseen by usual mechanisms. Many drug therapy developments consist in investigating through different clinical trials…

定量方法 · 定量生物学 2020-03-31 Ezequiel Alvarez , Federico Lamagna , Manuel Szewc

We present a new approach to the problems of evaluating and learning personalized decision policies from observational data of past contexts, decisions, and outcomes. Only the outcome of the enacted decision is available and the historical…

机器学习 · 统计学 2019-06-04 Nathan Kallus