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Coronal Mass Ejections (CMEs) are the most energetic expulsions of magnetized plasma from the Sun that play a crucial role in space weather dynamics. This study investigates the diverse kinematics and thermodynamic evolution of two CMEs…

太阳与恒星天体物理 · 物理学 2023-10-11 Soumyaranjan Khuntia , Wageesh Mishra , Sudheer K Mishra , Yuming Wang , Jie Zhang , Shaoyu Lyu

We investigate the dynamics of entanglement in the excitation transfer through a chain of interacting molecules. In the case of two-molecule coupled to noisy environments we show that entanglement can be further enhanced if the distance…

量子物理 · 物理学 2015-08-18 Wei Song , Yi-Sheng Huang , Ming Yang , Zhuo-Liang Cao

Conformational changes are observed in many enzymes, but their role in catalysis is highly controversial. Here we present a theoretical model that illustrates how rigid catalysts can be fundamentally limited and how a conformational change…

生物大分子 · 定量生物学 2023-08-10 Olivier Rivoire

A relationship between the preexponent of the rate constant and the distribution over activation barrier energies for enzymatic/protein reactions is revealed. We consider an enzyme solution as an ensemble of individual molecules with…

生物大分子 · 定量生物学 2012-11-16 A. E. Sitnitsky

In living cells, molecular motors create activity that enhances the diffusion of particles throughout the cytoplasm, and not just ones attached to the motors. We demonstrate initial steps toward creating artificial cells that mimic this…

软凝聚态物质 · 物理学 2019-05-01 Viva R. Horowitz , Zachary C. Chambers , İrep Gözen , Thomas G. Dimiduk , Vinothan N. Manoharan

Reactions with enzymes are critical in biochemistry, where the enzymes act as catalysis in the process. One of the most used mechanisms for modeling enzyme-catalyzed reactions is the Michaelis-Menten (MM) kinetic. In the ODE level, i.e.…

偏微分方程分析 · 数学 2023-03-15 Bao Quoc Tang , Bao-Ngoc Tran

In a single molecule assay, the motion of a molecular motor is often inferred from measuring the stochastic trajectory of a large probe particle attached to it. We discuss a simple model for this generic set-up taking into account…

统计力学 · 物理学 2012-11-22 Eva Zimmermann , Udo Seifert

We found evidence of dynamic scaling in the spreading of MDCK monolayer, which can be characterized by the Hurst exponent ${\alpha} = 0.86$ and the growth exponent ${\beta} = 0.73$, and theoretically and experimentally clarified the…

细胞行为 · 定量生物学 2021-01-04 Toshiki Oguma , Hisako Takigawa-Imamura , Takashi Miura

Recent experiments reveal both passive subdiffusion of various nanoparticles and anomalous active transport of such particles by molecular motors in the molecularly crowded environment of living biological cells. Passive and active…

生物物理 · 物理学 2014-03-24 Igor Goychuk , Vasyl O. Kharchenko , R. Metzler

Dynamic cooperativity in monomeric enzymes is characterized in terms of a non-Michaelis-Menten kinetic behaviour. The latter is believed to be associated with mechanisms that include multiple reaction pathways due to enzymatic…

化学物理 · 物理学 2016-09-21 Ashutosh Kumar , Sambarta Chatterjee , Mintu Nandi , Arti Dua

Push-pull networks are ubiquitous in signal transduction pathways in both prokaryotic and eukaryotic cells. They allow cells to strongly amplify signals via the mechanism of zero-order ultrasensitivity. In a push-pull network, two…

分子网络 · 定量生物学 2007-08-28 Siebe B. van Albada , Pieter Rein ten Wolde

A systematic expansion of the many-body master equation for active matter, in which motors power configurational changes as in the cytoskeleton, is shown to yield a description of the steady state and responses in terms of an effective…

软凝聚态物质 · 物理学 2011-08-08 Shenshen Wang , Peter G. Wolynes

The role of incoherent tunneling in the diffusion of light atoms on surfaces is investigated. With this purpose, a Chudley-Elliot master equation constrained to nearest neighbors is considered within the Grabert-Weiss approach to quantum…

统计力学 · 物理学 2013-09-10 A. S. Sanz , R. Martinez-Casado , S. Miret-Artes

Switch-like motifs are among the basic building blocks of biochemical networks. A common motif that can serve as an ultrasensitive switch consists of two enzymes acting antagonistically on a substrate, one making and the other removing a…

分子网络 · 定量生物学 2023-05-31 Jeremy A. Owen , Pranay Talla , John W. Biddle , Jeremy Gunawardena

We examine the dependence of the physical quantities of the rotatory molecular motor, such as the rotation velocity and the proton translocation rate, on the chemical reaction rate using the model based only on diffusion process. A peculiar…

生物物理 · 物理学 2009-11-10 Hiroshi Miki , Masatoshi Sato , Mahito Kohmoto

Recent results have shown the appearance of induced cooperative motions called dynamic heterogeneity during the isomerization of diluted azobenzene molecules in a host glass-former. In this paper we raise the issue of the coupling between…

软凝聚态物质 · 物理学 2015-06-19 Victor Teboul , Jean-Baptiste Accary

Fueled by the hydrolysis of ATP, the motor protein kinesin literally walks on two legs along the biopolymer microtubule. The number of accidental backsteps that kinesin takes appears to be much larger than what one would expect given the…

亚细胞过程 · 定量生物学 2009-11-13 M. Bier , F. J. Cao

The mechanics of cells is strongly affected by molecular motors that generate forces in the cellular cytoskeleton. We develop a model for cytoskeletal networks driven out of equilibrium by molecular motors exerting transient contractile…

软凝聚态物质 · 物理学 2009-11-13 Fred C. MacKintosh , Alex J. Levine

The step motions considered are those in which crystallization is controlled by a single diffusion process, either the substance diffusion for growth from solution or the flow of latent heat from the step for growth from melt. Quasi-static…

凝聚态物理 · 物理学 2009-10-22 Serge Yu. Potapenko

Recently individual two-headed kinesin molecules have been studied in in vitro motility assays revealing a number of their peculiar transport properties. In this paper we propose a simple and robust model for the kinesin stepping process…

统计力学 · 物理学 2009-10-31 Imre Derenyi , Tamas Vicsek