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The reconstruction of cerebral cortex surfaces from brain MRI scans is instrumental for the analysis of brain morphology and the detection of cortical thinning in neurodegenerative diseases like Alzheimer's disease (AD). Moreover, for a…

神经元与认知 · 定量生物学 2022-10-05 Anne-Marie Rickmann , Fabian Bongratz , Sebastian Pölsterl , Ignacio Sarasua , Christian Wachinger

The human brain cortical layer has a convoluted morphology that is unique to each individual. Characterization of the cortical morphology is necessary in longitudinal studies of structural brain change, as well as in discriminating…

计算机视觉与模式识别 · 计算机科学 2018-10-25 Sevil Maghsadhagh , Mousa Shamsi , Anders Eklund , Hamid Behjat

This paper considers the problem of brain disease classification based on connectome data. A connectome is a network representation of a human brain. The typical connectome classification problem is very challenging because of the small…

In recent years, new and important perspectives were introduced in the field of neuroimaging with the emergence of the connectionist approach. In this new context, it is important to know not only which brain areas are activated by a…

神经元与认知 · 定量生物学 2019-04-17 Jean Faber , Priscila C. Antoneli , Guillem Via , Noemi S. Araújo , Daniel J. L. L. Pinheiro , Esper Cavalheiro

Connectomics and network neuroscience offer quantitative scientific frameworks for modeling and analyzing networks of structurally and functionally interacting neurons, neuronal populations, and macroscopic brain areas. This shift in…

神经元与认知 · 定量生物学 2020-10-06 Richard Betzel

In our previous study we have shown that the female connectomes have significantly better, deep graph-theoretical parameters, related to superior "connectivity", than the connectome of the males. Since the average female brain is smaller…

神经元与认知 · 定量生物学 2015-12-04 Balázs Szalkai , Bálint Varga , Vince Grolmusz

In this paper, we develop an approach to modeling high-dimensional networks with a large number of nodes arranged in a hierarchical and modular structure. We propose a novel multi-scale factor analysis (MSFA) model which partitions the…

应用统计 · 统计学 2020-04-10 Chee-Ming Ting , Hernando Ombao , Sh-Hussain Salleh

The human brain cortical layer has a convoluted morphology that is unique to each individual. Characterization of the cortical morphology is necessary in longitudinal studies of structural brain change, as well as in discriminating…

神经元与认知 · 定量生物学 2019-02-21 Sevil Maghsadhagh , Anders Eklund , Hamid Behjat

The introduction of graph theory in neuroimaging has pro- vided invaluable tools for the study of brain connectivity. These methods require the definition of a graph, which is typically derived by estimating the effective connectivity…

统计方法学 · 统计学 2016-12-19 Nicolas Honnorat , Christos Davatzikos

One of the central problems in neuroscience is understanding how brain structure relates to function. Naively one can relate the direct connections of white matter fiber tracts between brain regions of interest (ROIs) to the increased…

神经元与认知 · 定量生物学 2023-08-30 Haoming Yang , Steven Winter , Zhengwu Zhang , David Dunson

Functional brain network properties are heavily influenced by how the the network nodes are defined. A common approach uses Regions of Interest (ROIs), i.e., predetermined collections of functional magnetic resonance imaging (fMRI)…

神经元与认知 · 定量生物学 2025-03-07 Tarmo Nurmi , Pietro De Luca , Maria Hakonen , Mikko Kivelä , Onerva Korhonen

The application of graph theory to model the complex structure and function of the brain has shed new light on its organization and function, prompting the emergence of network neuroscience. Despite the tremendous progress that has been…

信号处理 · 电气工程与系统科学 2020-09-29 Giulia Lioi , Vincent Gripon , Abdelbasset Brahim , François Rousseau , Nicolas Farrugia

Brain parcellations play a ubiquitous role in the analysis of magnetic resonance imaging (MRI) datasets. Over 100 years of research has been conducted in pursuit of an ideal brain parcellation. Different methods have been developed and…

神经元与认知 · 定量生物学 2021-07-09 Pantea Moghimi , Anh The Dang , Theoden I. Netoff , Kelvin O. Lim , Gowtham Atluri

The connectome is a wiring diagram mapping all the neural connections in the brain. At the cellular level, it provides a map of the neurons and synapses within a part or all of the brain of an organism. In recent years, significant advances…

神经元与认知 · 定量生物学 2022-06-01 Adrián Hernández , José M. Amigó

We present a hybrid method that performs the complete parcellation of the cerebral cortex of an individual, based on the connectivity information of the white matter fibers from a whole-brain tractography dataset. The method consists of…

神经元与认知 · 定量生物学 2020-02-24 Narciso López-López , Andrea Vázquez , Cyril Poupon , Jean-François Mangin , Pamela Guevara

Recent neuroimaging studies have shown that functional connectomes are unique to individuals, i.e., two distinct fMRIs taken over different sessions of the same subject are more similar in terms of their connectomes than those from two…

计算机视觉与模式识别 · 计算机科学 2019-08-12 Vikram Ravindra , Petros Drineas , Ananth Grama

In the face of the stupefying complexity of the human brain, network analysis is a most useful tool that allows one to greatly simplify the problem, typically by approximating the billions of neurons comprising the brain by means of a…

神经元与认知 · 定量生物学 2023-10-03 Youssef Kora , Christoph Simon

The underlying anatomical structure is fundamental to the study of brain networks, but the role of brainstem from a structural perspective is not very well understood. We conduct a computational and graph-theoretical study of the human…

神经元与认知 · 定量生物学 2023-04-26 Salma Salhi , Youssef Kora , Gisu Ham , Hadi Zadeh Haghighi , Christoph Simon

Brain connectome analysis commonly compresses high-resolution brain scans (typically composed of millions of voxels) down to only hundreds of regions of interest (ROIs) by averaging within-ROI signals. This huge dimension reduction improves…

统计方法学 · 统计学 2025-03-25 Tong Lu , Yuan Zhang , Peter Kochunov , Elliot Hong , Shuo Chen

In this work we focus on examination and comparison of whole-brain functional connectivity patterns measured with fMRI across experimental conditions. Direct examination and comparison of condition-specific matrices is challenging due to…

应用统计 · 统计学 2013-01-02 Svetlana V. Shinkareva , Vladimir Gudkov , Jing Wang