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Acute infection, if not rapidly and accurately detected, can lead to sepsis, organ failure and even death. Current detection of acute infection as well as assessment of a patient's severity of illness are imperfect. Characterization of a…

We develop a scalable multi-step Monte Carlo algorithm for inference under a large class of nonparametric Bayesian models for clustering and classification. Each step is "embarrassingly parallel" and can be implemented using the same Markov…

统计计算 · 统计学 2018-06-08 Yang Ni , Peter Müller , Maurice Diesendruck , Sinead Williamson , Yitan Zhu , Yuan Ji

Classically, Bayesian clustering interprets each component of a mixture model as a cluster. The inferred clustering posterior is highly sensitive to any inaccuracies in the kernel within each component. As this kernel is made more flexible,…

统计方法学 · 统计学 2025-12-12 David Buch , Miheer Dewaskar , David B. Dunson

Survey data are often collected under multistage sampling designs where units are binned to clusters that are sampled in a first stage. The unit-indexed population variables of interest are typically dependent within cluster. We propose a…

统计方法学 · 统计学 2021-08-26 Luis G. Leon-Novelo , Terrance D. Savitsky

Clustering analysis plays an important role in scientific research and commercial application. K-means algorithm is a widely used partition method in clustering. However, it is known that the K-means algorithm may get stuck at suboptimal…

神经与进化计算 · 计算机科学 2014-05-26 M. H. Marghny , Rasha M. Abd El-Aziz , Ahmed I. Taloba

High-throughput sequencing technology provides unprecedented opportunities to quantitatively explore human gut microbiome and its relation to diseases. Microbiome data are compositional, sparse, noisy, and heterogeneous, which pose serious…

统计方法学 · 统计学 2020-10-12 Fangting Zhou , Kejun He , Qiwei Li , Robert S. Chapkin , Yang Ni

Cluster analysis is a popular unsupervised learning tool used in many disciplines to identify heterogeneous sub-populations within a sample. However, validating cluster analysis results and determining the number of clusters in a data set…

机器学习 · 统计学 2024-04-26 Ali Turfah , Xiaoquan Wen

As single-cell gene expression data analysis continues to grow, the need for reliable clustering methods has become increasingly important. The prevalence of heuristic means for method choice could lead to inaccurate reports if…

定量方法 · 定量生物学 2026-05-19 Owen Visser , Somnath Datta

Clustering is one of the most widely used procedures in the analysis of microarray data, for example with the goal of discovering cancer subtypes based on observed heterogeneity of genetic marks between different tissues. It is well-known…

统计方法学 · 统计学 2009-04-21 Heng Lian

In data containing heterogeneous subpopulations, classification performance benefits from incorporating the knowledge of cluster structure in the classifier. Previous methods for such combined clustering and classification either 1) are…

机器学习 · 计算机科学 2023-01-04 Shivin Srivastava , Siddharth Bhatia , Lingxiao Huang , Lim Jun Heng , Kenji Kawaguchi , Vaibhav Rajan

This paper presents a multiple learner algorithm called the 'Three Ensemble Clustering 3EC' algorithm that classifies unlabeled data into quality clusters as a part of unsupervised learning. It offers the flexibility to explore the context…

机器学习 · 计算机科学 2021-07-09 Kundu , Debasish

Over the last decade, a large variety of clustering algorithms have been developed to detect coregulatory relationships among genes from microarray gene expression data. Model based clustering approaches have emerged as statistically well…

定量方法 · 定量生物学 2008-01-15 Anagha Joshi , Yves Van de Peer , Tom Michoel

Predictive marker patterns in imaging data are a means to quantify disease and progression, but their identification is challenging, if the underlying biology is poorly understood. Here, we present a method to identify predictive texture…

计算机视觉与模式识别 · 计算机科学 2020-02-11 Matthias Perkonigg , Daniel Sobotka , Ahmed Ba-Ssalamah , Georg Langs

Early risk diagnosis and driving anomaly detection from vehicle stream are of great benefits in a range of advanced solutions towards Smart Road and crash prevention, although there are intrinsic challenges, especially lack of ground truth,…

机器学习 · 计算机科学 2024-10-01 Xiupeng Shi , Yiik Diew Wong , Chen Chai , Michael Zhi-Feng Li , Tianyi Chen , Zeng Zeng

Bayesian nonparametric mixture models are widely used to cluster observations. However, one major drawback of the approach is that the estimated partition often presents unbalanced clusters' frequencies with only a few dominating clusters…

统计方法学 · 统计学 2026-02-03 Beatrice Franzolini , Giovanni Rebaudo

There are multiple cluster randomised trial designs that vary in when the clusters cross between control and intervention states, when observations are made within clusters, and how many observations are made at that time point. Identifying…

统计方法学 · 统计学 2023-07-20 Samuel I. Watson , Alan Girling , Karla Hemming

A model based clustering procedure for data of mixed type, clustMD, is developed using a latent variable model. It is proposed that a latent variable, following a mixture of Gaussian distributions, generates the observed data of mixed type.…

统计方法学 · 统计学 2015-11-06 Damien McParland , Isobel Claire Gormley

We consider comparisons of statistical learning algorithms using multiple data sets, via leave-one-in cross-study validation: each of the algorithms is trained on one data set; the resulting model is then validated on each remaining data…

应用统计 · 统计学 2015-06-02 Lorenzo Trippa , Levi Waldron , Curtis Huttenhower , Giovanni Parmigiani

Clustering is a widely used unsupervised learning method for finding structure in the data. However, the resulting clusters are typically presented without any guarantees on their robustness; slightly changing the used data sample or…

机器学习 · 统计学 2017-01-02 Andreas Henelius , Kai Puolamäki , Henrik Boström , Panagiotis Papapetrou

Background: When planning a cluster randomized trial, evaluators often have access to an enumerated cohort representing the target population of clusters. Practicalities of conducting the trial, such as the need to oversample clusters with…

统计方法学 · 统计学 2024-09-19 Sarah E. Robertson , Jon A. Steingrimsson , Issa J. Dahabreh