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Over the past decades, statisticians and machine-learning researchers have developed literally thousands of new tools for the reduction of high-dimensional data in order to identify the variables most responsible for a particular trait.…

机器学习 · 统计学 2012-05-31 Chamont Wang , Jana Gevertz , Chaur-Chin Chen , Leonardo Auslender

Microarray is a technology to quantitatively monitor the expression of large number of genes in parallel. It has become one of the main tools for global gene expression analysis in molecular biology research in recent years. The large…

定量方法 · 定量生物学 2015-06-18 Min Xu

For a medical diagnosis, health professionals use different kinds of pathological ways to make a decision for medical reports in terms of patients medical condition. In the modern era, because of the advantage of computers and technologies,…

机器学习 · 统计学 2021-06-08 Fahad B. Mostafa , Md Easin Hasan

We propose a new methodology for selecting and ranking covariates associated with a variable of interest in a context of high-dimensional data under dependence but few observations. The methodology successively intertwines the clustering of…

Dementia is a complex syndrome impacting cognitive and emotional functions, with Alzheimer's disease being the most common form. This study focuses on enhancing dementia prediction using machine learning (ML) techniques on patient health…

人工智能 · 计算机科学 2026-01-13 Shafiul Ajam Opee , Nafiz Fahad , Anik Sen , Rasel Ahmed , Fariha Jahan , Md. Kishor Morol , Md Rashedul Islam

In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The…

神经与进化计算 · 计算机科学 2024-01-12 Abeer Dyoub , Ivan Letteri

Background and Objective: Breast cancer, which accounts for 23% of all cancers, is threatening the communities of developing countries because of poor awareness and treatment. Early diagnosis helps a lot in the treatment of the disease. The…

定量方法 · 定量生物学 2020-11-24 Hamza Saad , Nagendra Nagarur

Chronic diseases are long-term, manageable, yet typically incurable conditions, highlighting the need for effective preventive strategies. Machine learning has been widely used to assess individual risk for chronic diseases. However, many…

机器学习 · 计算机科学 2025-06-24 Minh Le , Khoi Ton

This paper introduces a deep-learning based efficient classifier for common dermatological conditions, aimed at people without easy access to skin specialists. We report approximately 80% accuracy, in a situation where primary care doctors…

机器学习 · 统计学 2018-08-01 Sourav Mishra , Toshihiko Yamasaki , Hideaki Imaizumi

In this work we propose an approach to select the classification method and features, based on the state-of-the-art, with best performance for diagnostic support through peripheral blood smear images of red blood cells. In our case we used…

The classification of diabetes and prediabetes by static glucose thresholds obscures the pathophysiological dysglycemia heterogeneity, primarily driven by insulin resistance (IR), beta-cell dysfunction, and incretin deficiency. This review…

机器学习 · 计算机科学 2025-11-07 Ahmed A. Metwally , Heyjun Park , Yue Wu , Tracey McLaughlin , Michael P. Snyder

Machine learning (ML) has revolutionized medical prognostics by integrating advanced algorithms with clinical data to enhance disease prediction, risk assessment, and patient outcome forecasting. This comprehensive review critically…

机器学习 · 计算机科学 2024-08-06 Michael Fascia

Due to the rapid innovation of technology and the desire to find and employ biomarkers for neurodegenerative disease, high-dimensional data classification problems are routinely encountered in neuroimaging studies. To avoid over-fitting and…

机器学习 · 统计学 2018-06-19 Shan Shi , Farouk Nathoo

Clinical trials need to recruit a sufficient number of volunteer patients to demonstrate the statistical power of the treatment (e.g., a new drug) in curing a certain disease. Clinical trial recruitment has a significant impact on trial…

机器学习 · 计算机科学 2024-07-19 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

Electronic Health Records (EHRs) often lack explicit links between medications and diagnoses, making clinical decision-making and research more difficult. Even when links exist, diagnosis lists may be incomplete, especially during early…

计算与语言 · 计算机科学 2025-03-31 Dina Albassam , Adam Cross , Chengxiang Zhai

Currently, many researchers and analysts are working toward medical diagnosis enhancement for various diseases. Heart disease is one of the common diseases that can be considered a significant cause of mortality worldwide. Early detection…

机器学习 · 计算机科学 2023-06-02 Salahaldeen Rababa , Asma Yamin , Shuxia Lu , Ashraf Obaidat

Clinical diagnosis prediction models, when provided with a patient's medical history, aim to detect potential diseases early, facilitating timely intervention and improving prognostic outcomes. However, the inherent scarcity of patient data…

计算与语言 · 计算机科学 2025-01-30 Mingyu Derek Ma , Xiaoxuan Wang , Yijia Xiao , Anthony Cuturrufo , Vijay S Nori , Eran Halperin , Wei Wang

With the application of hematopoietic stem cell transplantation and new drugs, the progression-free survival rate and overall survival rate of multiple myeloma have been greatly improved, but it is still considered as a kind of disease that…

定量方法 · 定量生物学 2024-03-05 Jianfeng Chen , Jize Xiong , Yixu Wang , Qi Xin , Hong Zhou

Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Clinical predictions using clinical data by computational methods are common in bioinformatics. However, clinical predictions using information from genomics datasets as well is not a frequently observed phenomenon in research. Precision…

基因组学 · 定量生物学 2021-06-25 Moeez M. Subhani , Ashiq Anjum