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Rupture of intracranial aneurysms results in severe subarachnoidal hemorrhage, which is associated with high morbidity and mortality. Neurointerventional occlusion of the aneurysm through coiling has evolved to a therapeutical standard. The…

计算工程、金融与科学 · 计算机科学 2024-03-12 Julian Schwarting , Fabian Holzberger , Markus Muhr , Martin Renz , Tobias Boeckh-Behrens , Barbara Wohlmuth , Jan Kirschke

Endovascular coil embolization is one of the primary treatment techniques for cerebral aneurysms. Although it is a well established and minimally invasive method, it bears the risk of sub-optimal coil placement which can lead to incomplete…

计算工程、金融与科学 · 计算机科学 2024-02-06 Fabian Holzberger , Markus Muhr , Barbara Wohlmuth

Predicting the long-term success of endovascular interventions in the clinical management of cerebral aneurysms requires detailed insight into the patient-specific physiological conditions. In this work, we not only propose numerical…

Intracranial aneurysms remain a major cause of neurological morbidity and mortality worldwide, where rupture risk is tightly coupled to local hemodynamics particularly wall shear stress and oscillatory shear index. Conventional…

Endovascular treatment of cerebral aneurysms aims to achieve functional occlusion and isolation of the aneurysm sac from bloodflow. In clinical practice, treatment success is assessed primarily through digital subtraction angiography (DSA),…

计算工程、金融与科学 · 计算机科学 2026-05-06 Fabian Holzberger , Struan Hume , Markus Muhr , Malebogo Ngoepe , Barbara Wohlmuth

Intracranial aneurysms (IAs) are serious cerebrovascular lesions found in approximately 5\% of the general population. Their rupture may lead to high mortality. Current methods for assessing IA risk focus on morphological and…

Intrasaccular flow disruptors treat cerebral aneurysms by diverting the blood flow from the aneurysm sac. Residual flow into the sac after the intervention is a failure that could be due to the use of an undersized device, or to vascular…

Endovascular aneurysm repair (EVAR) is a current alternative treatment for thoracic and abdominal aortic aneurysms, but is still sometimes compromised by possible complications such as device migration or endoleaks. In order to assist…

医学物理 · 物理学 2019-02-05 V. Acosta Santamaría , G. Daniel , D. Perrin , J. Albertini , E. Rosset , S. Avril

The treatment of intracranial aneurysms (IA) relies on angiography guidance using biplane views. However, accurate flow estimation and device sizing for treatment are often compromised by vessel overlap and foreshortening, which can obscure…

Endovascular guidewire manipulation is essential for minimally-invasive clinical applications (Percutaneous Coronary Intervention (PCI), Mechanical thrombectomy techniques for acute ischemic stroke (AIS), or Transjugular intrahepatic…

机器人学 · 计算机科学 2023-04-20 Young-Ho Kim , Èric Lluch , Gulsun Mehmet , Florin C. Ghesu , Ankur Kapoor

Cerebral aneurysms affect three to five percent of the population, and rupture remains a major cause of stroke-related death and disability. Current therapies, surgical clipping, endovascular coiling, and flow diversion, have improved…

组织与器官 · 定量生物学 2025-09-25 Duong Le

We hereby present a full synthetic model, able to mimic the various constituents of the cerebral vascular tree, including the cerebral arteries, bifurcations and intracranial aneurysms. This model intends to provide a substantial dataset of…

计算机视觉与模式识别 · 计算机科学 2024-11-06 Rafic Nader , Florent Autrusseau , Vincent L'Allinec , Romain Bourcier

Intracranial aneurysms (IAs) are generally asymptomatic and thus often discovered incidentally on angiographic scans like 3D DSA, CTA and MRA. Skilled radiologists achieved a sensitivity of 88% by means of visual detection, which seems…

图像与视频处理 · 电气工程与系统科学 2020-06-01 Žiga Bizjak , Boštjan Likar , Franjo Pernuš , Žiga Špiclin

Computational fluid dynamics (CFD) studies have been increasingly used for blood flow simulations in intracranial aneurysms (ICAs). However, despite the continuous progress of body-fitted CFD solvers, generating a high quality mesh is still…

计算工程、金融与科学 · 计算机科学 2020-07-28 D. S. Lampropoulos , G. C. Bourantas , B. F. Zwick , G. C. Kagadis , A. Wittek , K. Miller , V. C. Loukopoulos

The precise segmentation of intracranial aneurysms and their parent vessels (IA-Vessel) is a critical step for hemodynamic analyses, which mainly depends on computational fluid dynamics (CFD). However, current segmentation methods…

计算机视觉与模式识别 · 计算机科学 2025-12-02 Feiyang Xiao , Yichi Zhang , Xigui Li , Yuanye Zhou , Chen Jiang , Xin Guo , Limei Han , Yuxin Li , Fengping Zhu , Yuan Cheng

Intracranial aneurysms are common nowadays and how to detect them intelligently is of great significance in digital health. While most existing deep learning research focused on medical images in a supervised way, we introduce an…

图像与视频处理 · 电气工程与系统科学 2022-01-19 Di Shao , Xuequan Lu , Xiao Liu

Predicting rupture risk and deciding on optimal treatment plan for intracranial aneurysms (IAs) is possible by quantification of their size and shape. For this purpose the IA has to be isolated from 3D angiogram. State-of-the-art methods…

图像与视频处理 · 电气工程与系统科学 2020-06-01 Žiga Bizjak , Boštjan Likar , Franjo Pernuš , Žiga Špiclin

We hereby present a full synthetic model, able to mimic the various constituents of the cerebral vascular tree: the cerebral arteries, the bifurcations and the intracranial aneurysms. By building this model, our goal was to provide a…

图像与视频处理 · 电气工程与系统科学 2024-03-28 Rafic Nader , Florent Autrusseau , Vincent L'Allinec , Romain Bourcier

Intracranial aneurysms (IAs) are abnormal dilations of cerebral blood vessels that, if ruptured, can lead to life-threatening consequences. However, their small size and soft contrast in radiological scans often make it difficult to perform…

图像与视频处理 · 电气工程与系统科学 2025-08-04 Erin Rainville , Amirhossein Rasoulian , Hassan Rivaz , Yiming Xiao

Intracranial aneurysms (IAs), characterized by unpredictable growth and risk of rupture, are a major cause of stroke and can lead to life-threatening hemorrhages with high mortality and long-term disability. With aging populations, the…

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