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During morphogenesis, the shape of a tissue emerges from collective cellular behaviors, which are in part regulated by mechanical and biochemical interactions between cells. Quantification of force and stress is therefore necessary to…

组织与器官 · 定量生物学 2014-02-19 K. Sugimura , Y. Bellaïche , F. Graner , P. Marcq , S. Ishihara

Integrating experimental data into simulations is crucial for predicting material behaviour, especially in fracture mechanics. Digital Image Correlation (DIC) provides precise displacement measurements, essential for evaluating strain…

计算工程、金融与科学 · 计算机科学 2025-06-17 Abdalrhaman Koko , T. James Marrow

Wound geometry and the mechanical properties of human skin govern the failure modes of partially healed or scarred tissue. Though dermatologists and surgeons develop an intuitive understanding of the mechanical characteristics of skin…

医学物理 · 物理学 2025-07-30 Congzhou M Sha

The outcome of vertebroplasty is hard to predict due to its dependence on complex factors like bone cement and marrow rheologies. Cement leakage could occur if the procedure is done incorrectly, potentially causing adverse complications. A…

Regulation, legal liabilities, and societal concerns challenge the adoption of AI in safety and security-critical applications. One of the key concerns is that adversaries can cause harm by manipulating model predictions without being…

机器学习 · 计算机科学 2023-01-31 Jona Klemenc , Holger Trittenbach

Goal: A limitation in robotic surgery is the lack of force feedback, due to challenges in suitable sensing techniques. To enhance the perception of the surgeons and precise force rendering, estimation of these forces along with tissue…

系统与控制 · 电气工程与系统科学 2025-04-30 Srikar Annamraju , Yuxi Chen , Jooyoung Lim , Inki Kim

The mechanics of puncture and soft solid penetration is commonly explored with the assumption of frictionless contact between the needle (penetrator) and the specimen. This leads to the hypothesis of a constant penetration force.…

软凝聚态物质 · 物理学 2024-12-04 Stefano Fregonese , Mattia Bacca

The present endeavor numerically exploits the use of a phase-field model to simulate and investigate fracture patterns, deformation mechanisms, damage, and mechanical responses in a human vertebra after the incision of pedicle screws under…

计算工程、金融与科学 · 计算机科学 2023-06-21 Deison Preve , Pietro Lenarda , Daniele Bianchi , Alessio Gizzi

Metastases increase the risk of fracture when affecting the femur. Consequently, clinicians need to know if the patients femur can withstand the stress of daily activities. The current tools used in clinics are not sufficiently precise. A…

In this paper, we extend the recently proposed extended scaled boundary finite element method (xSBFEM)~\cite{natarajansong2013} to study fracture parameters of interfacial cracks and cracks terminating at the interface. The approach is also…

数值分析 · 数学 2014-07-14 Sundararajan Natarajan , Chongmin Song , Salim Belouettar

Purpose: We propose a mathematical framework for quantitative analysis weighting the impact of heterogeneous components of a surgery. While multi-level approaches, surgical process modeling and other workflow analysis methods exist, this is…

其他计算机科学 · 计算机科学 2017-02-03 Asli Okur , Ralf Stauder , Hubertus Feussner , Nassir Navab

In this work, the finite elements method (FEM) is used to analyse the growth of fretting cracks. FEM can be favourably used to extract the stress intensity factors in mixed mode, a typical situation for cracks growing in the vicinity of a…

地球物理 · 物理学 2011-02-24 Henry Proudhon , Stéphanie Basseville

Cutting mechanics of soft solids is gaining rapid attention thanks to its promising benefits in material characterization and other applications. However, a full understanding of the physical phenomena is still missing, and several…

软凝聚态物质 · 物理学 2024-12-04 Bharath Antarvedi Goda , Zhenwei Ma , Stefano Fregonese , Mattia Bacca

Finite element analysis is one of the most used tool for studying femoral neck fracture. Nerveless, consensus concerning either the choice of material characteristics, damage law and /or geometric models (linear on nonlinear) still remains…

We present multiscale models of cancer tumor invasion with components at the molecular, cellular, and tissue levels. We provide biological justifications for the model components, present computational results from the model, and discuss…

定量方法 · 定量生物学 2023-02-14 Bruce P. Ayati , Glenn F. Webb , Alexander R. A. Anderson

A key goal of empirical research in software engineering is to assess practical significance, which answers whether the observed effects of some compared treatments show a relevant difference in practice in realistic scenarios. Even though…

A suitable piece of software is presented to connect Abaqus, a sophisticated finite element package, with Matlab, the most comprehensive program for mathematical analysis. This interface between these well-known codes not only benefits from…

数学软件 · 计算机科学 2017-11-29 George Papazafeiropoulos , Miguel Muñiz-Calvente , Emilio Martínez-Pañeda

We study experimentally the slow growth of a single crack in a fibrous material and observe stepwise growth dynamics. We model the material as a lattice where the crack is pinned by elastic traps and grows due to thermally activated stress…

统计力学 · 物理学 2009-11-10 Stephane Santucci , Loic Vanel , Sergio Ciliberto

We present a discrete stochastic model which represents many of the salient features of the biological process of wound healing. The model describes fronts of cells invading a wound. We have numerical results in one and two dimensions. In…

细胞行为 · 定量生物学 2009-11-11 Thomas Callaghan , Evgeniy Khain , Leonard M. Sander , Robert M. Ziff

Tactile afferents such as (RA), and Pacinian (PC) afferents that respond to external stimuli enable complicated actions such as grasping, stroking and identifying an object. To understand the tactile sensation induced by these actions…

机器人学 · 计算机科学 2022-08-02 Hiroki Ishizuka , Shoki Kitaguchi , Masashi Nakatani , Hidenori Yoshimura , Fusao Shimokawa