English

A stochastic model for wound healing

Cell Behavior 2009-11-11 v1

Abstract

We present a discrete stochastic model which represents many of the salient features of the biological process of wound healing. The model describes fronts of cells invading a wound. We have numerical results in one and two dimensions. In one dimension we can give analytic results for the front speed as a power series expansion in a parameter, p, that gives the relative size of proliferation and diffusion processes for the invading cells. In two dimensions the model becomes the Eden model for p near 1. In both one and two dimensions for small p, front propagation for this model should approach that of the Fisher-Kolmogorov equation. However, as in other cases, this discrete model approaches Fisher-Kolmogorov behavior slowly.

Keywords

Cite

@article{arxiv.q-bio/0507035,
  title  = {A stochastic model for wound healing},
  author = {Thomas Callaghan and Evgeniy Khain and Leonard M. Sander and Robert M. Ziff},
  journal= {arXiv preprint arXiv:q-bio/0507035},
  year   = {2009}
}

Comments

16 pages, 7 figures

R2 v1 2026-07-22T19:24:30.663Z