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Studying the cellular architecture of the human cerebral cortex is critical for understanding brain organization and function. It requires investigating complex texture patterns in histological images, yet automatic methods that scale…

The field of computational modeling of the brain is advancing so rapidly that now it is possible to model large scale networks representing different brain regions with a high level of biological detail in terms of numbers and synapses. For…

Functional Magnetic Resonance Image (fMRI) is commonly employed to study human brain activity, since it offers insight into the relationship between functional fluctuations and human behavior. To enhance analysis and comprehension of brain…

人工智能 · 计算机科学 2025-02-04 Song Wang , Zhenyu Lei , Zhen Tan , Jiaqi Ding , Xinyu Zhao , Yushun Dong , Guorong Wu , Tianlong Chen , Chen Chen , Aiying Zhang , Jundong Li

Magnetic resonance imaging~(MRI) have played a crucial role in brain disease diagnosis, with which a range of computer-aided artificial intelligence methods have been proposed. However, the early explorations usually focus on the limited…

计算机视觉与模式识别 · 计算机科学 2023-09-14 Jiayu Lei , Lisong Dai , Haoyun Jiang , Chaoyi Wu , Xiaoman Zhang , Yao Zhang , Jiangchao Yao , Weidi Xie , Yanyong Zhang , Yuehua Li , Ya Zhang , Yanfeng Wang

This paper considers the problem of brain disease classification based on connectome data. A connectome is a network representation of a human brain. The typical connectome classification problem is very challenging because of the small…

Sustainable research on computational models of neuronal networks requires published models to be understandable, reproducible, and extendable. Missing details or ambiguities about mathematical concepts and assumptions, algorithmic…

A major challenge in neuroscience is posed by the need for relating the emerging dynamical features of brain activity with the underlying modular structure of neural connections, hierarchically organized throughout several scales. The…

神经元与认知 · 定量生物学 2016-06-03 Pablo Villegas , Jorge Hidalgo , Paolo Moretti , Miguel A. Muñoz

The connectome is a wiring diagram mapping all the neural connections in the brain. At the cellular level, it provides a map of the neurons and synapses within a part or all of the brain of an organism. In recent years, significant advances…

神经元与认知 · 定量生物学 2022-06-01 Adrián Hernández , José M. Amigó

The goal of diffusion-weighted magnetic resonance imaging (DWI) is to infer the structural connectivity of an individual subject's brain in vivo. To statistically study the variability and differences between normal and abnormal brain…

神经元与认知 · 定量生物学 2023-03-06 Haocheng Dai , Martin Bauer , P. Thomas Fletcher , Sarang Joshi

Encoding brain regions and their connections as a network of nodes and edges captures many of the possible paths along which information can be transmitted as humans process and perform complex behaviors. Because cognitive processes involve…

神经元与认知 · 定量生物学 2016-12-21 Ann Sizemore , Chad Giusti , Ari Kahn , Richard F. Betzel , Danielle S. Bassett

Advanced brain imaging techniques make it possible to measure individuals' structural connectomes in large cohort studies non-invasively. The structural connectome is initially shaped by genetics and subsequently refined by the environment.…

应用统计 · 统计学 2018-06-11 Zhengwu Zhang , Genevera I. Allen , Hongtu Zhu , David Dunson

Publicly available data is essential for the progress of medical image analysis, in particular for crafting machine learning models. Glioma is the most common group of primary brain tumors, and magnetic resonance imaging (MRI) is a widely…

图像与视频处理 · 电气工程与系统科学 2024-10-28 Meryem Abbad Andaloussi , Raphael Maser , Frank Hertel , François Lamoline , Andreas Dominik Husch

Human brain contains about 10 billion neurons, each of which has about 10~10,000 nerve endings from which neurotransmitters are released in response to incoming spikes, and the released neurotransmitters then bind to receptors located in…

神经元与认知 · 定量生物学 2012-03-06 Xuejuan Zhang , Jianfeng Feng

Recent advances in neuroimaging along with algorithmic innovations in statistical learning from network data offer a unique pathway to integrate brain structure and function, and thus facilitate revealing some of the brain's organizing…

信号处理 · 电气工程与系统科学 2021-12-21 Yang Li , Gonzalo Mateos , Zhengwu Zhang

Understanding how the human brain represents visual concepts, and in which brain regions these representations are encoded, remains a long-standing challenge. Decades of work have advanced our understanding of visual representations, yet…

计算机视觉与模式识别 · 计算机科学 2025-12-15 Navve Wasserman , Matias Cosarinsky , Yuval Golbari , Aude Oliva , Antonio Torralba , Tamar Rott Shaham , Michal Irani

An unprecedented amount of existing functional Magnetic Resonance Imaging (fMRI) data provides a new opportunity to understand the relationship between functional fluctuation and human cognition/behavior using a data-driven approach. To…

机器学习 · 计算机科学 2024-09-18 Jiaqi Ding , Tingting Dan , Ziquan Wei , Hyuna Cho , Paul J. Laurienti , Won Hwa Kim , Guorong Wu

Graph deep learning models, a class of AI-driven approaches employing a message aggregation mechanism, have gained popularity for analyzing the functional brain connectome in neuroimaging. However, their actual effectiveness remains…

神经与进化计算 · 计算机科学 2026-02-10 Keqi Han , Yao Su , Lifang He , Liang Zhan , Sergey Plis , Vince Calhoun , Carl Yang

We propose a new framework, called Hierarchical Multi-resolution Mesh Networks (HMMNs), which establishes a set of brain networks at multiple time resolutions of fMRI signal to represent the underlying cognitive process. The suggested…

神经与进化计算 · 计算机科学 2017-01-13 Itir Onal Ertugrul , Mete Ozay , Fatos Tunay Yarman Vural

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

神经元与认知 · 定量生物学 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

Multimodal brain networks characterize complex connectivities among different brain regions from both structural and functional aspects and provide a new means for mental disease analysis. Recently, Graph Neural Networks (GNNs) have become…

神经元与认知 · 定量生物学 2022-05-25 Yanqiao Zhu , Hejie Cui , Lifang He , Lichao Sun , Carl Yang