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相关论文: Periodic Concentration-Polarization-Based Formatio…

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Concentration polarization (CP) based biomolecule preconcentration is highly effective in enhancing the detection sensitivity, yet fails to precisely and dynamically control the location of the preconcentrated biomolecule plug to ensure…

软凝聚态物质 · 物理学 2019-10-14 Sinwook Park , Gilad Yossifon

Ion transport in perm-selective media has been extensively investigated in recent years owing to its applications in advancements of fundamental understanding of nanoscale electrokinetics as well as innovative engineering applications. A…

流体动力学 · 物理学 2019-10-31 Junsuk Kim , Keon Huh , Ali Mani , Sung Jae Kim

We demonstrate a method of concentrating and patterning of biological cells on a chip, exploiting the confluence of electric and thermal fields, without necessitating the use of any external heating or illuminating source. The technique…

This paper studies mechanism of preconcentration of charged particles in a straight micro-channel embedded with permselective membranes, by numerically solving coupled transport equations of ions, charged particles and solvent fluid without…

流体动力学 · 物理学 2018-02-14 Zirui Li , Wei Liu , Yudan Zhu , Xiaohua Lu , Yuantong Gu , Jongyoon Han

Plasmonic biosensing chips were prepared by fabricating wavelength-scaled dielectric-metal interfacial gratings on polymer film covered bimetal layers. Lysozyme biomolecules (LYZ) and gold nanoparticle bioconjugates (AuNP-LYZ) with 1:5 mass…

The ability to induce regions of high and low ionic concentration adjacent to a permeselective membrane or nanochannel subject to an externally applied electric field (a phenomenon termed concentration-polarization) has been used for a…

流体动力学 · 物理学 2018-03-12 Sinwook Park , Gilad Yossifon

CO2 capture is a pressing global environmental issue that drives scientists to develop creative strategies for tackling this challenge. The concept in this contribution is to produce site specific nitrogen doping in microporous carbon…

应用物理 · 物理学 2018-10-16 Jiang Gong , Markus Antonietti , Jiayin Yuan

The optimal functioning of nanopore-based biosensing tools necessitates rapid polymer capture from the ion reservoir. We identify an ionic correlation-induced transport mechanism that provides this condition without the chemical…

软凝聚态物质 · 物理学 2018-05-10 Sahin Buyukdagli

We develop the first theoretical model for the analytical description of ion concentration polarization (ICP)-based electrokinetic molecular concentration, which had not been possible due to the extraordinary complexity of the system. We…

流体动力学 · 物理学 2018-01-08 Wei Ouyang , Zirui Li , Xinghui Ye , Jongyoon Han

Accounting for concentration-polarization (CP) is critical for modeling solute transport in membrane separation processes. In a mixed-electrolyte solution, ions CP is affected not only by diffusion and advection but also by…

软凝聚态物质 · 物理学 2021-08-05 Yaeli S. Oren , Viatcheslav Freger , Oded Nir

Locating the center of convex objects is important in both image processing and unsupervised machine learning/data clustering fields. The automated analysis of biological images uses both of these fields for locating cell nuclei and for…

计算机视觉与模式识别 · 计算机科学 2018-04-12 James Kapaldo , Xu Han , Domingo Mery

Photoelectrochemical (PEC) biosensors exhibit significant potential for biomolecule detection due to their high sensitivity and low background noise. However, their performance is severely constrained by the rapid recombination of…

Parahydrogen-Induced Polarization (PHIP) is a potent technique for generating target molecules with high nuclear spin polarization. The PHIP process involves a chemical reaction between parahydrogen and a target molecule, followed by the…

Cellular bioelectricity describes the biological phenomenon in which cells in living tissue generate and maintain patterns of voltage gradients induced by differing concentrations of charged ions. A growing body of research suggests that…

分布式、并行与集群计算 · 计算机科学 2018-09-27 Seth Gilbert , James Maguire , Calvin Newport

Controlling the polarization state of electromagnetic radiation enables the investigation of fundamental symmetry properties of matter through chiroptical processes. Many strategies have been developed to reveal structural or dynamical…

Silicon-based photonic biosensors, such as microring resonators and Mach-Zehnder interferometers, offer significant potential for the detection of analytes at low concentrations. To enhance response time and improve the limit of detection…

光学 · 物理学 2024-07-01 Anders Henriksson , Peter Neubauer , Mario Birkholz

Photonic crystals (PCs) with localized optical cavity modes arising from topological domain-wall line defects are simulated for optical biosensing by numerical solution of Maxwell's equations. These consist of a square lattice of square…

光学 · 物理学 2026-01-06 Zhengzheng Zhai , Sajeev John

Ion concentration polarization (CP, current-induced concentration gradient adjacent to a charge-selective interface) has been well studied for single-phase mixed conductors (e.g., liquid electrolyte), but multiphase CP has been rarely…

材料科学 · 物理学 2022-12-21 Huanhuan Tian , Ju Li , Martin Bazant

Accurately and quickly binuclear cell (BC) detection plays a significant role in predicting the risk of leukemia and other malignant tumors. However, manual microscopy counting is time-consuming and lacks objectivity. Moreover, with the…

计算机视觉与模式识别 · 计算机科学 2022-08-29 Baomin Wang , Geng Hu , Dan Chen , Lihua Hu , Cheng Li , Yu An , Guiping Hu , Guang Jia

Kinetic rate constants fundamentally characterize the dynamics of the chemical interaction of macromolecules, and thus their study sets a major direction in experimental biochemistry. The estimation of such constants is often challenging,…

定量方法 · 定量生物学 2017-08-04 József Vass , Sergey N. Krylov
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