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相关论文: An Interventionist Approach to Mediation Analysis

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Direct effect analyses usually require deciding whether a focal variable is a pre-exposure confounder or a post-exposure mediator. In observational studies, that distinction may be unclear because timing is measured coarsely or the variable…

统计方法学 · 统计学 2026-04-13 AmirEmad Ghassami

Mediation analysis in causal inference typically concentrates on one binary exposure, using deterministic interventions to split the average treatment effect into direct and indirect effects through a single mediator. Yet, real-world…

统计方法学 · 统计学 2023-07-07 David B. McCoy , Alan E. Hubbard , Mark van der Laan , Alejandro Schuler

To investigate causal mechanisms, causal mediation analysis decomposes the total treatment effect into the natural direct and indirect effects. This paper examines the estimation of the direct and indirect effects in a general treatment…

统计理论 · 数学 2024-01-24 Lukang Huang , Wei Huang , Oliver Linton , Zheng Zhang

An important problem in causal inference is to break down the total effect of a treatment on an outcome into different causal pathways and to quantify the causal effect in each pathway. For instance, in causal fairness, the total effect of…

机器学习 · 统计学 2022-01-10 Lu Cheng , Ruocheng Guo , Huan Liu

Researchers are often interested in learning not only the effect of treatments on outcomes, but also the pathways through which these effects operate. A mediator is a variable that is affected by treatment and subsequently affects outcome.…

统计方法学 · 统计学 2021-12-22 Jeremiah Jones , Ashkan Ertefaie , Robert L. Strawderman

Causal mediation analysis concerns the pathways through which a treatment affects an outcome. While most of the mediation literature focuses on settings with a single mediator, a flourishing line of research has examined settings involving…

统计方法学 · 统计学 2021-11-12 Xiang Zhou

We consider mediated effects of an exposure, X on an outcome, Y, via a mediator, M, under no unmeasured confounding assumptions in the setting where models for the conditional expectation of the mediator and outcome are partially linear. We…

统计方法学 · 统计学 2025-01-08 Oliver Hines , Stijn Vansteelandt , Karla Diaz-Ordaz

Causal mediation analysis can improve understanding of the mechanisms underlying epidemiologic associations. However, the utility of natural direct and indirect effect estimation has been limited by the assumption of no confounder of the…

应用统计 · 统计学 2020-06-16 Kara E. Rudolph , Oleg Sofrygin , Wenjing Zheng , Mark J. van der Laan

Most work in causal inference considers deterministic interventions that set each unit's treatment to some fixed value. However, under positivity violations these interventions can lead to non-identification, inefficiency, and effects with…

统计方法学 · 统计学 2018-06-20 Edward H. Kennedy

Interventional effects have been proposed as a solution to the unidentifiability of natural (in)direct effects under mediator-outcome confounders affected by the exposure. Such confounders are an intrinsic characteristic of studies with…

统计方法学 · 统计学 2022-03-30 Iván Díaz , Nicholas Williams , Kara E. Rudolph

This paper aims to provide practitioners of causal mediation analysis with a better understanding of estimation options. We take as inputs two familiar strategies (weighting and model-based prediction) and a simple way of combining them…

Counterfactual explanations (CEs) are methods for generating an alternative scenario that produces a different desirable outcome. For example, if a student is predicted to fail a course, then counterfactual explanations can provide the…

机器学习 · 统计学 2023-01-09 Bevan I. Smith

Causal inference seeks to estimate the effect of an intervention on an outcome using observed data, typically via Rubin's potential-outcome framework or Pearl's do-calculus. Following section 9 of Richardson and Robins (2013), this essay…

统计方法学 · 统计学 2026-05-19 Christian Bartels

In this paper, we introduce a new causal methodology that accounts for the rarity and frequency of events in observational studies based on their relevance to the underlying problem. Specifically, we propose a direct causal effect metric…

人工智能 · 计算机科学 2025-02-28 Usef Faghihi , Amir Saki

The natural indirect effect (NIE) and mediation proportion (MP) are two measures of primary interest in mediation analysis. The standard approach for estimating NIE and MP is through the product method, which involves a model for the…

统计方法学 · 统计学 2021-08-20 Chao Cheng , Donna Spiegelman , Fan Li

The decomposition of the overall effect of a treatment into direct and indirect effects is here investigated with reference to a recursive system of binary random variables. We show how, for the single mediator context, the marginal effect…

统计方法学 · 统计学 2025-11-14 Martina Raggi , Elena Stanghellini , Marco Doretti

Mediation analysis plays a crucial role in causal inference as it can investigate the pathways through which treatment influences outcome. Most existing mediation analysis assumes that mediation effects are static and homogeneous within…

统计方法学 · 统计学 2026-03-02 Yijiao Zhang , Yubai Yuan , Yuexia Zhang , Zhongyi Zhu , Annie Qu

Probabilistic graphical models are a fundamental tool in statistics, machine learning, signal processing, and control. When such a model is defined on a directed acyclic graph (DAG), one can assign a partial ordering to the events occurring…

信息论 · 计算机科学 2011-10-05 Maxim Raginsky

Causal mediation analysis is routinely conducted by applied researchers in a variety of disciplines. The goal of such an analysis is to investigate alternative causal mechanisms by examining the roles of intermediate variables that lie in…

统计方法学 · 统计学 2010-11-05 Kosuke Imai , Luke Keele , Teppei Yamamoto

We propose a definition for the average indirect effect of a binary treatment in the potential outcomes model for causal inference under cross-unit interference. Our definition is analogous to the standard definition of the average direct…

统计方法学 · 统计学 2022-01-13 Yuchen Hu , Shuangning Li , Stefan Wager