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A central question in multimodal neuroimaging analysis is to understand the association between two imaging modalities and to identify brain regions where such an association is statistically significant. In this article, we propose a…

统计方法学 · 统计学 2024-11-28 Moyan Li , Lexin Li , Jian Kang

Population pharmacokinetic (PK) modeling methods can be statistically classified as either parametric or nonparametric (NP). Each classification can be divided into maximum likelihood (ML) or Bayesian (B) approaches. In this paper we…

High-dimensional mixed data as a combination of both continuous and ordinal variables are widely seen in many research areas such as genomic studies and survey data analysis. Estimating the underlying correlation among mixed data is hence…

统计方法学 · 统计学 2018-09-18 Xiaoyun Quan , James G. Booth , Martin T. Wells

The paper presents a new copula based method for measuring dependence between random variables. Our approach extends the Maximum Mean Discrepancy to the copula of the joint distribution. We prove that this approach has several advantageous…

机器学习 · 计算机科学 2019-08-15 Barnabas Poczos , Zoubin Ghahramani , Jeff Schneider

We propose a flexible Bayesian approach for estimating the joint density of a multivariate outcome of interest in the presence of categorical covariates. Leveraging a Gaussian copula framework, our method effectively captures the dependence…

统计方法学 · 统计学 2026-04-10 Giovanni Toto , Peter Müller , Abhra Sarkar

Vine copulas are a useful statistical tool to describe the dependence structure between several random variables, especially when the number of variables is very large. When modeling data with vine copulas, one often is confronted with a…

统计方法学 · 统计学 2017-05-10 Matthias Killiches , Daniel Kraus , Claudia Czado

Undirected graphical models are widely used to model the conditional independence structure of vector-valued data. However, in many modern applications, for example those involving EEG and fMRI data, observations are more appropriately…

机器学习 · 统计学 2024-01-29 Boxin Zhao , Percy S. Zhai , Y. Samuel Wang , Mladen Kolar

Neural computation in biological and artificial networks relies on the nonlinear summation of many inputs. The structural connectivity matrix of synaptic weights between neurons is a critical determinant of overall network function, but…

神经元与认知 · 定量生物学 2022-07-01 Tirthabir Biswas , James E. Fitzgerald

The early detection of Alzheimer's disease (AD) requires an understanding of the relationships between a wide range of features. Conditional independencies and partial correlations are suitable measures for these relationships, because they…

应用统计 · 统计学 2025-01-22 Lucas Vogels , Reza Mohammadi , Marit Schoonhoven , S. Ilker Birbil , Martin Dyrba

Disease surveillance is essential not only for the prior detection of outbreaks but also for monitoring trends of the disease in the long run. In this paper, we aim to build a tactical model for the surveillance of dengue, in particular.…

应用统计 · 统计学 2020-08-11 Atlanta Chakraborty , Vijay Chandru

Gaussian processes (GPs) are ubiquitous tools for modeling and predicting continuous processes in physical and engineering sciences. This is partly due to the fact that one may employ a Gaussian process as an interpolator while facilitating…

统计理论 · 数学 2025-12-16 D. Andrew Brown , Peter Kiessler , John Nicholson

The characteristics and determinants of health and disease are often organised in space, reflecting our spatially extended nature. Understanding the influence of such factors requires models capable of capturing spatial relations. Though a…

Gaussian copulas are widely used to estimate multivariate distributions and relationships. We present algorithms for estimating Gaussian copula correlations that ensure differential privacy. We first convert data values into sets of two-way…

统计方法学 · 统计学 2026-01-08 Shuo Wang , Joseph Feldman , Jerome P. Reiter

Multi-dimensional functional data arises in numerous modern scientific experimental and observational studies. In this paper we focus on longitudinal functional data, a structured form of multidimensional functional data. Operating within a…

统计方法学 · 统计学 2019-09-20 John Shamshoian , Damla Senturk , Shafali Jeste , Donatello Telesca

A new class of copulas, termed the MGL copula class, is introduced. The new copula originates from extracting the dependence function of the multivariate generalized log-Moyal-gamma distribution whose marginals follow the univariate…

统计方法学 · 统计学 2021-08-23 Zhengxiao Li , Jan Beirlant , Liang Yang

We are studying the problems of modeling and inference for multivariate count time series data with Poisson marginals. The focus is on linear and log-linear models. For studying the properties of such processes we develop a novel conceptual…

统计方法学 · 统计学 2017-04-10 Paul Doukhan , Konstantinos Fokianos , Bård Støve , Dag Tjøstheim

Regression models are used in a wide range of applications providing a powerful scientific tool for researchers from different fields. Linear, or simple parametric, models are often not sufficient to describe complex relationships between…

机器学习 · 统计学 2021-11-24 Aliaksandr Hubin , Geir Storvik , Florian Frommlet

With our ability to record more neurons simultaneously, making sense of these data is a challenge. Functional connectivity is one popular way to study the relationship between multiple neural signals. Correlation-based methods are a set of…

神经元与认知 · 定量生物学 2017-06-09 Tiger W. Lin , Anup Das , Giri P. Krishnan , Maxim Bazhenov , Terrence J. Sejnowski

Creation of synthetic data models has represented a significant advancement across diverse scientific fields, but this technology also brings important privacy considerations for users. This work focuses on enhancing a non-parametric…

The application of Gaussian processes (GPs) to large data sets is limited due to heavy memory and computational requirements. A variety of methods has been proposed to enable scalability, one of which is to exploit structure in the kernel…

机器学习 · 计算机科学 2019-12-30 Jan Graßhoff , Alexandra Jankowski , Philipp Rostalski
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