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It is often of interest to study the association between covariates and the cumulative incidence of a right-censored time-to-event outcome. When time-varying covariates are measured on a fixed discrete time scale, it is desirable to account…

统计方法学 · 统计学 2026-04-28 Hongxiang Qiu , Marco Carone , Alex Luedtke , Peter B. Gilbert

Genomic surveillance of infectious diseases allows monitoring circulating and emerging variants and quantifying their epidemic potential. However, due to the high costs associated with genomic sequencing, only a limited number of samples…

We consider a longitudinal data structure consisting of baseline covariates, time-varying treatment variables, intermediate time-dependent covariates, and a possibly time dependent outcome. Previous studies have shown that estimating the…

统计理论 · 数学 2018-10-09 Linh Tran , Maya Petersen , Joshua Schwab , Mark J van der Laan

Theoretical guarantees for causal inference using propensity scores are partly based on the scores behaving like conditional probabilities. However, scores between zero and one, especially when outputted by flexible statistical estimators,…

统计方法学 · 统计学 2024-11-12 Rom Gutman , Ehud Karavani , Yishai Shimoni

A key issue for all observational causal inference is that it relies on an unverifiable assumption - that observed characteristics are sufficient to proxy for treatment confounding. In this paper we argue that in medical cases these…

应用统计 · 统计学 2023-03-14 Alexander Peysakhovich , Yin Aphinyanaphongs

A deterministic model with testing of infected individuals has been proposed to investigate the potential consequences of the impact of testing strategy. The model exhibits global dynamics concerning the disease-free and a unique endemic…

种群与进化 · 定量生物学 2023-05-24 Sarita Bugalia , Jai Prakash Tripathi

Spurious association arises from covariance between propensity for the treatment and individual risk for the outcome. For sensitivity analysis with stochastic counterfactuals we introduce a methodology to characterize uncertainty in causal…

统计方法学 · 统计学 2021-03-11 Brian Knaeble , Braxton Osting , Placede Tshiaba

The paper presents some models for the propensity score. Considerable attention is given to a recently popular, but relatively under-explored setting in causal inference where the no-interference assumption does not hold. We lay out some…

统计方法学 · 统计学 2022-08-16 Hyunseung Kang , Chan Park , Ralph Trane

One of the central difficulties of addressing the COVID-19 pandemic has been accurately measuring and predicting the spread of infections. In particular, official COVID-19 case counts in the United States are under counts of actual…

物理与社会 · 物理学 2024-05-20 Daniel Smolyak , Saad Abrar , Naman Awasthi , Vanessa Frias-Martinez

We describe a class of algorithms for evaluating posterior moments of certain Bayesian linear regression models with a normal likelihood and a normal prior on the regression coefficients. The proposed methods can be used for hierarchical…

统计计算 · 统计学 2021-10-08 Philip Greengard , Jeremy Hoskins , Charles C. Margossian , Andrew Gelman , Aki Vehtari

We address the setting of Proxy Causal Learning (PCL), which has the goal of estimating causal effects from observed data in the presence of hidden confounding. Proxy methods accomplish this task using two proxy variables related to the…

机器学习 · 计算机科学 2026-03-27 Bariscan Bozkurt , Ben Deaner , Dimitri Meunier , Liyuan Xu , Arthur Gretton

The estimation of unknown parameters in simulations, also known as calibration, is crucial for practical management of epidemics and prediction of pandemic risk. A simple yet widely used approach is to estimate the parameters by minimizing…

统计方法学 · 统计学 2023-06-26 Chih-Li Sung , Ying Hung

As a reaction to the pandemic of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a multitude of clinical trials for the treatment of SARS-CoV-2 or the resulting corona disease (COVID-19) are globally at various stages from…

应用统计 · 统计学 2020-12-04 Jan Beyersmann , Tim Friede , Claudia Schmoor

Partial identification approaches are a flexible and robust alternative to standard point-identification approaches in general instrumental variable models. However, this flexibility comes at the cost of a ``curse of cardinality'': the…

计量经济学 · 经济学 2020-06-30 Florian Gunsilius

We develop a statistical model for the testing of disease prevalence in a population. The model assumes a binary test result, positive or negative, but allows for biases in sample selection and both type I (false positive) and type II…

应用统计 · 统计学 2021-12-28 Lucas Böttcher , Maria R. D'Orsogna , Tom Chou

Three critical issues for causal inference that often occur in modern, complicated experiments are interference, treatment nonadherence, and missing outcomes. A great deal of research efforts has been dedicated to developing causal…

统计方法学 · 统计学 2023-04-06 Yuki Ohnishi , Arman Sabbaghi

There are very different statistical methods for demonstrating a trend in pharmacological experiments. Here, the focus is on sparse models with only one parameter to be estimated and interpreted: the increase in the regression model and the…

应用统计 · 统计学 2020-07-21 Ludwig A. Hothorn

Statistical methods for causal inference with continuous treatments mainly focus on estimating the mean potential outcome function, commonly known as the dose-response curve. However, it is often not the dose-response curve but its…

统计方法学 · 统计学 2025-04-21 Yikun Zhang , Yen-Chi Chen

The proximal causal inference framework enables the identification and estimation of causal effects in the presence of unmeasured confounding by leveraging two disjoint sets of observed strong proxies: negative control treatments and…

统计方法学 · 统计学 2025-12-16 Antonio Olivas-Martinez , Peter B. Gilbert , Andrea Rotnitzky

Facing a global epidemic of new infectious diseases such as COVID-19, non-pharmaceutical interventions (NPIs), which reduce transmission rates without medical actions, are being implemented around the world to mitigate spreads. One of the…

种群与进化 · 定量生物学 2021-03-04 Naoya Fujiwara , Tomokatsu Onaga , Takayuki Wada , Shouhei Takeuchi , Junji Seto , Tomoki Nakaya , Kazuyuki Aihara
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