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Electron Cryo-Tomography (ECT) enables 3D visualization of macromolecule structure inside single cells. Macromolecule classification approaches based on convolutional neural networks (CNN) were developed to separate millions of…

定量方法 · 定量生物学 2018-03-28 Jialiang Guo , Bo Zhou , Xiangrui Zeng , Zachary Freyberg , Min Xu

Purpose: To develop and evaluate the accuracy of a multi-view deep learning approach to the analysis of high-resolution synthetic mammograms from digital breast tomosynthesis screening cases, and to assess the effect on accuracy of image…

图像与视频处理 · 电气工程与系统科学 2020-09-29 Saeed Seyyedi , Margaret J. Wong , Debra M. Ikeda , Curtis P. Langlotz

In transmission X-ray microscopy (TXM) systems, the rotation of a scanned sample might be restricted to a limited angular range to avoid collision to other system parts or high attenuation at certain tilting angles. Image reconstruction…

图像与视频处理 · 电气工程与系统科学 2020-01-09 Yixing Huang , Shengxiang Wang , Yong Guan , Andreas Maier

The prospect of neural reconstruction from Electron Microscopy (EM) images has been elucidated by the automatic segmentation algorithms. Although segmentation algorithms eliminate the necessity of tracing the neurons by hand, significant…

计算机视觉与模式识别 · 计算机科学 2015-09-29 Toufiq Parag

Cryo-EM is a vital technique for determining 3D structure of biological molecules such as proteins and viruses. The cryo-EM reconstruction problem is challenging due to the high noise levels, the missing poses of particles, and the…

定量方法 · 定量生物学 2024-06-05 Larissa de Ruijter , Gabriele Cesa

Computational microwave imaging (CMI) has gained attention as an alternative technique for conventional microwave imaging techniques, addressing their limitations such as hardware-intensive physical layer and slow data collection…

信号处理 · 电气工程与系统科学 2025-05-09 Cien Zhang , Jiaming Zhang , Jiajun He , Okan Yurduseven

We report resolution enhancement in scanning electron microscopy (SEM) images using a generative adversarial network. We demonstrate the veracity of this deep learning-based super-resolution technique by inferring unresolved features in…

计算机视觉与模式识别 · 计算机科学 2019-08-21 Kevin de Haan , Zachary S. Ballard , Yair Rivenson , Yichen Wu , Aydogan Ozcan

Single-beam scanning electron microscopes (SEM) are widely used to acquire massive data sets for biomedical study, material analysis, and fabrication inspection. Datasets are typically acquired with uniform acquisition: applying the…

图像与视频处理 · 电气工程与系统科学 2021-01-11 Lu Mi , Hao Wang , Yaron Meirovitch , Richard Schalek , Srinivas C. Turaga , Jeff W. Lichtman , Aravinthan D. T. Samuel , Nir Shavit

Recent advancements in deep learning for automated image processing and classification have accelerated many new applications for medical image analysis. However, most deep learning applications have been developed using reconstructed,…

计算机视觉与模式识别 · 计算机科学 2018-12-05 Hyunkwang Lee , Chao Huang , Sehyo Yune , Shahein H. Tajmir , Myeongchan Kim , Synho Do

Cryogenic electron tomography is a technique for imaging biological samples in 3D. A microscope collects a series of 2D projections of the sample, and the goal is to reconstruct the 3D density of the sample called the tomogram.…

计算机视觉与模式识别 · 计算机科学 2024-08-13 Simon Wiedemann , Reinhard Heckel

Electron cryotomography (CryoET) is currently the only method capable of visualizing cells in 3D at nanometer resolutions. While modern instruments produce massive amounts of tomography data containing extremely rich structural information,…

定量方法 · 定量生物学 2021-07-01 Muyuan Chen , James M. Bell , Xiaodong Shi , Stella Y. Sun , Zhao Wang , Steven J. Ludtke

Accurate determination of three-dimensional (3D) atomic structures is crucial for understanding and controlling the properties of nanomaterials. Atomic electron tomography (AET) offers non-destructive atomic imaging with picometer-level…

材料科学 · 物理学 2025-06-23 Juhyeok Lee , Yongsoo Yang

Brain-related disorders such as epilepsy can be diagnosed by analyzing electroencephalograms (EEG). However, manual analysis of EEG data requires highly trained clinicians, and is a procedure that is known to have relatively low inter-rater…

信号处理 · 电气工程与系统科学 2018-05-21 Subhrajit Roy , Isabell Kiral-Kornek , Stefan Harrer

Gliomas are brain tumor types that have a high mortality rate which means early and accurate diagnosis is important for therapeutic intervention for the tumors. To address this difficulty, the proposed research will develop a hybrid deep…

计算机视觉与模式识别 · 计算机科学 2025-11-27 Pandiyaraju V , Sreya Mynampati , Abishek Karthik , Poovarasan L , D. Saraswathi

Reconstructing a map of neuronal connectivity is a critical challenge in contemporary neuroscience. Recent advances in high-throughput serial section electron microscopy (EM) have produced massive 3D image volumes of nanoscale brain tissue…

The goal of cryo-electron microscopy (EM) is to reconstruct the 3-dimensional structure of a molecule from a collection of its 2-dimensional projected images. In this article, we show that the basic premise of cryo-EM --- patching together…

计算机视觉与模式识别 · 计算机科学 2017-04-25 Ke Ye , Lek-Heng Lim

The diagnosis of brain cancer relies heavily on medical imaging techniques, with MRI being the most commonly used. It is necessary to perform automatic segmentation of brain tumors on MRI images. This project intends to build an MRI…

图像与视频处理 · 电气工程与系统科学 2024-06-28 Yuxiang Hu , Haowei Yang , Ting Xu , Shuyao He , Jiajie Yuan , Haozhang Deng

The recent development of deep learning large models in medicine shows remarkable performance in medical image analysis and diagnosis, but their large number of parameters causes memory and inference latency challenges. Knowledge…

计算机视觉与模式识别 · 计算机科学 2024-09-19 Shaojie Li , Zhaoshuo Diao

Cellular Electron CryoTomography (CECT) is a 3D imaging technique that captures information about the structure and spatial organization of macromolecular complexes within single cells, in near-native state and at sub-molecular resolution.…

定量方法 · 定量生物学 2018-07-04 Kai Wen Wang , Xiangrui Zeng , Xiaodan Liang , Zhiguang Huo , Eric P. Xing , Min Xu

Light guide plates are essential optical components widely used in a diverse range of applications ranging from medical lighting fixtures to back-lit TV displays. An essential step in the manufacturing of light guide plates is the quality…

图像与视频处理 · 电气工程与系统科学 2022-04-26 Carol Xu , Mahmoud Famouri , Gautam Bathla , Mohammad Javad Shafiee , Alexander Wong