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This paper is motivated by the analysis of a survey study of college student wellbeing before and after the outbreak of the COVID-19 pandemic. A statistical challenge in well-being survey studies lies in that outcome variables are often…

统计方法学 · 统计学 2023-06-09 Shaobo Li , Zhaohu Fan , Ivy Liu , Philip S. Morrison , Dungang Liu

We consider the problem of estimating the effects of a binary treatment on a continuous outcome of interest from observational data in the absence of confounding by unmeasured factors. We provide a new estimator of the population average…

统计方法学 · 统计学 2020-08-04 James Robins , Mariela Sued , Quanhong Lei-Gomez , Andrea Rotnitzky

Randomized trials are considered the gold standard for estimating causal effects. Trial findings are often used to inform policy and programming efforts, yet their results may not generalize well to a relevant target population due to…

Statisticians have recently developed propensity score methods to improve generalizations from randomized experiments that do not employ random sampling. However, these methods typically rely on assumptions whose plausibility may be…

统计方法学 · 统计学 2019-11-14 Wendy Chan

The propensity score analysis is one of the most widely used methods for studying the causal treatment effect in observational studies. This paper studies treatment effect estimation with the method of matching weights. This method…

统计方法学 · 统计学 2011-05-17 Liang Li

Monitoring the progression of neurodegenerative disease (NDD) has important applications in planning treatment and evaluating new medications. Whereas much work has focused on discriminating patients from healthy controls, or predicting…

音频与语音处理 · 电气工程与系统科学 2026-05-05 Jacob J Webber , Oliver Watts , Lovisa Wihlborg , Johnny Tam , Christine Weaver , Suvankar Pal , Siddharthan Chandran , Cassia Valentini-Botinhao

The opioid epidemic is a crisis that has plagued the United States (US) for decades. One central issue is inequitable access to treatment for opioid use disorder (OUD), which puts certain populations at a higher risk of opioid overdose. We…

物理与社会 · 物理学 2024-03-14 Joyce Luo , Bartolomeo Stellato

Non-linear mixed effects modeling and simulation (NLME M&S) is evaluated to be used for standardization with longitudinal data in presence of confounders. Standardization is a well-known method in causal inference to correct for confounding…

统计方法学 · 统计学 2024-05-01 Christian Bartels , Martina Scauda , Neva Coello , Thomas Dumortier , Bjoern Bornkamp , Giusi Moffa

Many estimators of the average effect of a treatment on an outcome require estimation of the propensity score, the outcome regression, or both. It is often beneficial to utilize flexible techniques such as semiparametric regression or…

统计方法学 · 统计学 2019-05-14 Cheng Ju , David Benkeser , Mark J. van der Laan

Structural Equation/Causal Models (SEMs/SCMs) are widely used in epidemiology and social sciences to identify and analyze the average causal effect (ACE) and conditional ACE (CACE). Traditional causal effect estimation methods such as…

机器学习 · 计算机科学 2022-05-03 Sourabh Balgi , Jose M. Pena , Adel Daoud

This paper introduces a universal approach to seamlessly combine out-of-distribution (OOD) detection scores. These scores encompass a wide range of techniques that leverage the self-confidence of deep learning models and the anomalous…

机器学习 · 统计学 2024-06-25 Eduardo Dadalto , Florence Alberge , Pierre Duhamel , Pablo Piantanida

In recent years, the US has experienced an opioid epidemic with an unprecedented number of drugs overdose deaths. Research finds such overdose deaths are linked to neighborhood-level traits, thus providing opportunity to identify effective…

机器学习 · 计算机科学 2021-12-07 Sachin Gavali , Chuming Chen , Julie Cowart , Xi Peng , Shanshan Ding , Cathy Wu , Tammy Anderson

Matching is a widely used causal inference design that aims to approximate a randomized experiment using observational data by forming matched sets of treated and control units based on similarities in their covariates. Ideally, treated…

统计方法学 · 统计学 2026-04-06 Jianan Zhu , Jeffrey Zhang , Zijian Guo , Siyu Heng

This chapter presents an overview of a specific form of limited dependent variable models, namely discrete choice models, where the dependent (response or outcome) variable takes values which are discrete, inherently ordered, and…

计量经济学 · 经济学 2023-05-30 Mohit Batham , Soudeh Mirghasemi , Mohammad Arshad Rahman , Manini Ojha

Evidence for Action (E4A), a signature program of the Robert Wood Johnson Foundation, funds investigator-initiated research on the impacts of social programs and policies on population health and health inequities. Across thousands of…

Stroke remains a leading cause of death and disability worldwide, yet effective prediction of stroke risk using large-scale population data remains challenging due to data imbalance and high-dimensional features. In this study, we develop…

应用统计 · 统计学 2025-10-28 Jinbo Niu

We study identifying and estimating the causal effect of a treatment variable on a long-term outcome using data from an observational and an experimental domain. The observational data are subject to unobserved confounding. Furthermore,…

Drug overdose deaths, including from opioids, remain a significant public health threat to the United States (US). To abate the harms of opioid misuse, understanding its prevalence at the local level is crucial for stakeholders in…

应用统计 · 统计学 2026-01-09 Zixuan Feng , Qiushi Chen , Paul Griffin , Le Bao

Practitioners in diverse fields such as healthcare, economics and education are eager to apply machine learning to improve decision making. The cost and impracticality of performing experiments and a recent monumental increase in electronic…

机器学习 · 计算机科学 2023-08-01 Fredrik D. Johansson , Uri Shalit , Nathan Kallus , David Sontag

This work considers the problem of binary classification: given training data $x_1, \dots, x_n$ from a certain population, together with associated labels $y_1,\dots, y_n \in \left\{0,1 \right\}$, determine the best label for an element $x$…

统计理论 · 数学 2016-07-04 Nicolas Garcia Trillos , Ryan Murray