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In the last two decades, functional magnetic resonance imaging (fMRI) has emerged as one of the most effective technologies in clinical research of the human brain. fMRI allows researchers to study healthy and pathological brains while they…

神经元与认知 · 定量生物学 2022-12-06 Sadi Md. Redwan , Md Palash Uddin , Muhammad Imran Sharif , Anwaar Ulhaq

Deep Learning (DL) in neuroimaging has become increasingly relevant for detecting neurological conditions and neurodegenerative disorders. One of the most predominant biomarkers in neuroimaging is represented by brain age, which has been…

图像与视频处理 · 电气工程与系统科学 2025-11-20 Carlo Alberto Barbano , Matteo Brunello , Benoit Dufumier , Marco Grangetto

Diagnosing cognitive (mental health) disorders is a delicate and complex task. Identifying the next most informative symptoms to assess, in order to distinguish between possible disorders, presents an additional challenge. This process…

信息检索 · 计算机科学 2025-11-25 Raoul H. Kutil , Georg Zimmermann , Christian Borgelt

Complex functional brain network analyses have exploded over the last eight years, gaining traction due to their profound clinical implications. The application of network science (an interdisciplinary offshoot of graph theory) has…

统计方法学 · 统计学 2013-10-28 Sean L. Simpson , F. DuBois Bowman , Paul J. Laurienti

Speech patterns have been identified as potential diagnostic markers for neuropsychiatric conditions. However, most studies only compare a single clinical group to healthy controls, whereas clinical practice often requires differentiating…

Psychiatric illnesses are often associated with multiple symptoms, whose severity must be graded for accurate diagnosis and treatment. This grading is usually done by trained clinicians based on human observations and judgments made within…

声音 · 计算机科学 2017-03-17 Rita Singh , Justin Baker , Luciana Pennant , Louis-Philippe Morency

Functional magnetic resonance imaging (fMRI) aims to locate activated regions in human brains when specific tasks are performed. The conventional tool for analyzing fMRI data applies some variant of the linear model, which is restrictive in…

统计理论 · 数学 2008-08-08 Chunming Zhang , Tao Yu

Functional Magnetic Resonance Imaging (fMRI) is commonly utilized to study human brain activity, including abnormal functional properties related to neurodegenerative diseases. This study aims to investigate the differences in the…

神经元与认知 · 定量生物学 2023-05-17 Yongcheng Yao

People with Multiple Sclerosis (MS) complain of problems with hand dexterity and cognitive fatigue. However, in many cases, impairments are subtle and difficult to detect. Functional near-infrared spectroscopy (fNIRS) is a non-invasive…

机器学习 · 计算机科学 2025-09-29 Sadman Saumik Islam , Bruna Dalcin Baldasso , Davide Cattaneo , Xianta Jiang , Michelle Ploughman

Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis,…

人工智能 · 计算机科学 2023-02-24 Mianxin Liu , Jingyang Zhang , Yao Wang , Yan Zhou , Fang Xie , Qihao Guo , Feng Shi , Han Zhang , Qian Wang , Dinggang Shen

The insufficient supervision limit the performance of the deep supervised models for brain disease diagnosis. It is important to develop a learning framework that can capture more information in limited data and insufficient supervision. To…

神经元与认知 · 定量生物学 2024-10-10 Wenjing Gao , Yuanyuan Yang , Jianrui Wei , Xuntao Yin , Xinhan Di

Segmentation of focal (localized) brain pathologies such as brain tumors and brain lesions caused by multiple sclerosis and ischemic strokes are necessary for medical diagnosis, surgical planning and disease development as well as other…

计算机视觉与模式识别 · 计算机科学 2017-01-25 Mohammad Havaei , Nicolas Guizard , Hugo Larochelle , Pierre-Marc Jodoin

We aim to develop clustering models to obtain behavioral representations from continuous multimodal mobile sensing data towards relapse prediction tasks. The identified clusters could represent different routine behavioral trends related to…

机器学习 · 计算机科学 2022-02-22 Joanne Zhou , Bishal Lamichhane , Dror Ben-Zeev , Andrew Campbell , Akane Sano

By promising more accurate diagnostics and individual treatment recommendations, deep neural networks and in particular convolutional neural networks have advanced to a powerful tool in medical imaging. Here, we first give an introduction…

机器学习 · 计算机科学 2023-01-23 Fabian Eitel , Marc-André Schulz , Moritz Seiler , Henrik Walter , Kerstin Ritter

By focusing on melancholic features with biological homogeneity, this study aimed to identify a small number of critical functional connections (FCs) that were specific only to the melancholic type of MDD. On the resting-state fMRI data,…

The standard approach to the analysis of functional magnetic resonance imaging (FMRI) data applies various preprocessing steps to the original FMRI. These preprocessings lead to a general underestimation of residual variance in the…

应用统计 · 统计学 2018-09-20 Thomas Wilhelm Dieter Möbius

Current psychiatric research is in crisis. In this review I will describe the causes of this crisis and highlight recent efforts to overcome current challenges. One particularly promising approach is the emerging field of computational…

神经元与认知 · 定量生物学 2013-03-25 Thomas V. Wiecki

The objective of this chapter is to provide a guide to using functional magnetic resonance imaging (fMRI) to inform cognitive theory. This is, of course, a daunting task, as the premise itself - that fMRI data can inform cognitive theory -…

神经元与认知 · 定量生物学 2015-07-08 Christopher H. Chatham , David Badre

Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Abdul Basit , Ashir Rashid , Muhammad Abdullah Hanif , Muhammad Shafique

Many analyses of functional magnetic resonance imaging (fMRI) examine functional connectivity (FC), or the statistical dependencies among distant brain regions. These analyses are typically exploratory, guiding future confirmatory research.…

应用统计 · 统计学 2025-10-20 Kyle Stanley , Nicole Lazar , Matthew Reimherr