相关论文: Optical tweezers approaches for probing multiscale…

Holographic optical tweezers use computer-generated holograms to create arbitrary three-dimensional configurations of single-beam optical traps useful for capturing, moving and transforming mesoscopic objects. Through a combination of…

Optical centrifuge has emerged as a promising tool for achieving centrifuge motion of particles in many fields. Herein, we report a novel optical centrifuge, as driven by optical lateral force arising from transverse phase gradient of light…

Inspired by recent successes using single-stranded DNA tiles to produce complex structures, we develop a two-step coarse-graining approach that uses detailed thermodynamic calculations with oxDNA, a nucleotide-based model of DNA, to…

We present a novel approach to determine the optical properties of materials in the nanoscale range using optical tweezers (OT). Fluorescent polymer-based nanostructures (pdots) are optically trapped in a Gaussian beam OT and the trap…

Collagen fibrils, cable-like assemblies of long biological molecules, are dominant components of connective tissues. Their determinant morphological and functional roles motivated a large number of studies concerning their formation and…

The prediction of the three-dimensional native structure of proteins from the knowledge of their amino acid sequence, known as the protein folding problem, is one of the most important yet unsolved issues of modern science. Since the…

Holographic Optical Tweezers (HOT) are powerful tools that can manipulate micro and nano-scale objects with high accuracy and precision. They are most commonly used for biological applications, such as cellular studies, and more recently,…

Intricate comparison between two given tertiary structures of proteins is as important as the comparison of their functions. Several algorithms have been devised to compute the similarity and dissimilarity among protein structures. But,…

Optical clocks based on atoms and ions achieve exceptional precision and accuracy, with applications to relativistic geodesy, tests of relativity, and searches for dark matter. Achieving such performance requires balancing competing…

We present a novel platform of optical tweezers which combines rapid prototyping of user-definable microlens arrays with spatial light modulation (SLM) for dynamical control of each associated tweezer spot. Applying femtosecond direct laser…

All light has structure, but only recently it has become possible to construct highly controllable and precise potentials so that most laboratories can harness light for their specific applications. In this chapter, we review the emerging…

Trapped atoms near nanophotonics form an exciting platform for bottom-up synthesis of strongly interacting quantum matter. The ability to induce tunable long-range atom-atom interactions with photons presents an opportunity to explore…

Optical transport networks for active absorbing microparticles are made with holographic optical tweezers. The particles are powered by the optical potentials that make the network and transport themselves via random vapor propelled hops to…

Dual trap optical tweezers are often used in high-resolution measurements in single-molecule biophysics. Such measurements can be hindered by the presence of extraneous noise sources, the most prominent of which is the coupling of…

Optical tweezers has emerged as a powerful tool in manipulating microscopic particles and in measuring weak forces of the order of a pico-Newton. As a result, it has found wide applications ranging from material science to biology.…

Chirality is a ubiquitous phenomenon in the natural world. Many biomolecules without inversion symmetry such as amino acids and sugars are chiral molecules. Measuring and controlling molecular chirality at a high precision down to the…

Normal thermal fluctuations of the cell membrane have been studied extensively using high resolution microscopy and focused light, particularly at the peripheral regions of a cell. We use a single probe particle attached non-specifically to…

Red blood cells possess unique biomechanical ability to squeeze through capillaries smaller than their size to enable gas and ion exchange. A key signature of their active biomechanics is the out-of-equilibrium fluctuation of the plasma…

Optical metasurfaces of subwavelength pillars have provided new capabilities for the versatile definition of the amplitude, phase, and polarization of light. In this work, we demonstrate that an efficient dielectric metasurface lens can be…

Plasmonic optical tweezers are a ubiquitous tool for the precise manipulation of nanoparticles and biomolecules at low photon flux, while femtosecond-laser optical tweezers can probe the nonlinear optical properties of the trapped species…