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Segmenting healthy tissue structures alongside lesions in brain Magnetic Resonance Images (MRI) remains a challenge for today's algorithms due to lesion-caused disruption of the anatomy and lack of jointly labeled training datasets, where…

图像与视频处理 · 电气工程与系统科学 2025-03-26 Meva Himmetoglu , Ilja Ciernik , Ender Konukoglu

Early diagnosis and accurate segmentation of brain tumors are imperative for successful treatment. Unfortunately, manual segmentation is time consuming, costly and despite extensive human expertise often inaccurate. Here, we present an…

图像与视频处理 · 电气工程与系统科学 2019-10-07 Markus Frey , Matthias Nau

Diffusion models have been increasingly used as strong generative priors for solving inverse problems such as super-resolution in medical imaging. However, these approaches typically utilize a diffusion prior trained at a single scale,…

图像与视频处理 · 电气工程与系统科学 2026-02-02 Darshan Thaker , Mahmoud Mostapha , Radu Miron , Shihan Qiu , Mariappan Nadar

Unsupervised anomaly detection has gained significant attention in the field of medical imaging due to its capability of relieving the costly pixel-level annotation. To achieve this, modern approaches usually utilize generative models to…

图像与视频处理 · 电气工程与系统科学 2024-01-22 Rui Xu , Yunke Wang , Bo Du

Unsupervised anomaly segmentation approaches to pathology segmentation train a model on images of healthy subjects, that they define as the 'normal' data distribution. At inference, they aim to segment any pathologies in new images as…

图像与视频处理 · 电气工程与系统科学 2024-06-06 Ziyun Liang , Xiaoqing Guo , J. Alison Noble , Konstantinos Kamnitsas

In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

图像与视频处理 · 电气工程与系统科学 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

One of the most important tasks in medical image processing is the brain's whole tumor segmentation. It assists in quicker clinical assessment and early detection of brain tumors, which is crucial for lifesaving treatment procedures of…

计算机视觉与模式识别 · 计算机科学 2020-09-15 Apurva Pandya , Catherine Samuel , Nisargkumar Patel , Vaibhavkumar Patel , Thangarajah Akilan

Statistical analysis of magnetic resonance imaging (MRI) can help radiologists to detect pathologies that are otherwise likely to be missed. Deep learning (DL) has shown promise in modeling complex spatial data for brain anomaly detection.…

计算机视觉与模式识别 · 计算机科学 2020-11-26 Victor Saase , Holger Wenz , Thomas Ganslandt , Christoph Groden , Máté E. Maros

Medical imaging data suffers from the limited availability of annotation because annotating 3D medical data is a time-consuming and expensive task. Moreover, even if the annotation is available, supervised learning-based approaches suffer…

图像与视频处理 · 电气工程与系统科学 2020-11-12 Abinav Ravi Venkatakrishnan , Seong Tae Kim , Rami Eisawy , Franz Pfister , Nassir Navab

Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

计算机视觉与模式识别 · 计算机科学 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers

Self-supervised learning methods based on image patch reconstruction have witnessed great success in training auto-encoders, whose pre-trained weights can be transferred to fine-tune other downstream tasks of image understanding. However,…

计算机视觉与模式识别 · 计算机科学 2022-09-20 Junjia Huang , Haofeng Li , Guanbin Li , Xiang Wan

Unsupervised anomaly detection methods offer a promising and flexible alternative to supervised approaches, holding the potential to revolutionize medical scan analysis and enhance diagnostic performance. In the current landscape, it is…

图像与视频处理 · 电气工程与系统科学 2023-08-29 Cosmin I. Bercea , Esther Puyol-Antón , Benedikt Wiestler , Daniel Rueckert , Julia A. Schnabel , Andrew P. King

Unsupervised anomaly detection (UAD) presents a complementary alternative to supervised learning for brain tumor segmentation in magnetic resonance imaging (MRI), particularly when annotated datasets are limited, costly, or inconsistent. In…

计算机视觉与模式识别 · 计算机科学 2025-10-20 Gerard Comas-Quiles , Carles Garcia-Cabrera , Julia Dietlmeier , Noel E. O'Connor , Ferran Marques

The quality of patient care associated with diagnostic radiology is proportionate to a physician workload. Segmentation is a fundamental limiting precursor to both diagnostic and therapeutic procedures. Advances in machine learning (ML) aim…

图像与视频处理 · 电气工程与系统科学 2022-08-30 Ahmed Ghorbel , Ahmed Aldahdooh , Shadi Albarqouni , Wassim Hamidouche

Unsupervised anomaly detection and segmentation methods train a model to learn the training distribution as `normal'. In the testing phase, they identify patterns that deviate from this normal distribution as `anomalies'. To learn the…

计算机视觉与模式识别 · 计算机科学 2025-10-16 Ziyun Liang , Xiaoqing Guo , Wentian Xu , Yasin Ibrahim , Natalie Voets , Pieter M Pretorius , J. Alison Noble , Konstantinos Kamnitsas

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

图像与视频处理 · 电气工程与系统科学 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer

Expert interpretation of anatomical images of the human brain is the central part of neuro-radiology. Several machine learning-based techniques have been proposed to assist in the analysis process. However, the ML models typically need to…

We propose a novel machine learning strategy for studying neuroanatomical shape variation. Our model works with volumetric binary segmentation images, and requires no pre-processing such as the extraction of surface points or a mesh. The…

计算机视觉与模式识别 · 计算机科学 2024-10-30 Evan M. Yu , Mert R. Sabuncu

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

图像与视频处理 · 电气工程与系统科学 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen