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We calculate the diffusion coefficient of an active tracer in a schematic crowded environment, represented as a lattice gas of passive particles with hardcore interactions. Starting from the master equation of the problem, we put forward a…

统计力学 · 物理学 2022-02-02 Pierre Rizkallah , Alessandro Sarracino , Olivier Bénichou , Pierre Illien

In this study, inspired by the work of K. Nakazato and K. Kitahara [Prog. Theor. Phys. 64, 2261 (1980)], we consider the theoretical problem of tracer particle diffusion in an environment of diffusing hardcore interacting crowder particles.…

Gradient-driven diffusion in crowded, multicomponent mixtures is a topic of high interest because of its role in biological processes such as transport in cell membranes. In partially phase-separated solutions, gradient-driven diffusion…

软凝聚态物质 · 物理学 2017-02-15 Prithviraj Nandigrami , Brandy Grove , Andrew Konya , Robin L. B. Selinger

Experimental studies of systems containing active proteins that undergo conformational changes driven by catalytic chemical reactions have shown that the diffusion coefficients of passive tracer particles and active molecules are larger…

软凝聚态物质 · 物理学 2017-02-27 Matthew Dennison , Raymond Kapral , Holger Stark

We analyze the dynamics of an active tracer particle embedded in a thermal lattice gas. All particles are subject to exclusion up to third nearest neighbors on the square lattice, which leads to slow dynamics at high densities. For the case…

软凝聚态物质 · 物理学 2019-04-15 Rakesh Chatterjee , Nimrod Segall , Carl Merrigan , Kabir Ramola , Bulbul Chakraborty , Yair Shokef

We summarise different results on the diffusion of a tracer particle in lattice gases of hard-core particles with stochastic dynamics, which are confined to narrow channels -- single-files, comb-like structures and quasi-one-dimensional…

统计力学 · 物理学 2018-11-14 O. Benichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez

A topic of intense current investigation pursues the question how the highly crowded environment of biological cells affects the dynamic properties of passively diffusing particles. Motivated by recent experiments we report results of…

统计力学 · 物理学 2016-09-28 Surya K. Ghosh , Andrey G. Cherstvy , Denis S. Grebenkov , Ralf Metzler

Crowded environments modify the diffusion of macromolecules, generally slowing their movement and inducing transient anomalous subdiffusion. The presence of obstacles also modifies the kinetics and equilibrium behavior of tracers. While…

We study the diffusion of a tracer particle, which moves in continuum space between a lattice of excluded volume, immobile non-inert obstacles. In particular, we analyse how the strength of the tracer-obstacle interactions and the volume…

软凝聚态物质 · 物理学 2014-12-24 Surya K. Ghosh , Andrey G. Cherstvy , Ralf Metzler

We study the diffusion of a tracer particle driven out-of-equilibrium by an external force and traveling in a dense environment of arbitrary density. The system evolves on a discrete lattice and its stochastic dynamics is described by a…

We study analytically the dynamics and the micro-structural changes of a host medium caused by a driven tracer particle moving in a confined, quiescent molecular crowding environment. Imitating typical settings of active micro-rheology…

统计力学 · 物理学 2016-03-17 O. Bénichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez

Diffusion in the crowded environments of the biological membranes or materials interfaces often involves intermittent binding to surface proteins or defects. To account for this situation we study a 2-dimensional lattice gas in a field of…

软凝聚态物质 · 物理学 2021-06-25 Mislav Cvitković , Dipanwita Ghanti , Niklas Raake , Ana-Sunčana Smith

Tracer-diffusion of small molecules through dense systems of chain polymers is studied within an athermal lattice model, where hard core interactions are taken into account by means of the site exclusion principle. An approximate mapping of…

软凝聚态物质 · 物理学 2009-11-07 O. Durr , T. Volz , W. Dieterich , A. Nitzan

Macromolecular diffusion in strongly confined geometries and crowded environments is still to a large extent an open subject in soft matter physics and biology. In this paper, we employ large-scale Langevin dynamics simulations to…

软凝聚态物质 · 物理学 2020-10-07 T. P. O. Nogueira , H. O. Frota , Francesco Piazza , José Rafael Bordin

This study uses a combination of stochastic optimization, statistical mechanical theory, and molecular simulation to test the extent to which the long-time dynamics of a single tracer particle can be enhanced by rationally modifying its…

软凝聚态物质 · 物理学 2011-11-24 James Carmer , Gaurav Goel , Mark J. Pond , Jeffrey R. Errington , Thomas M. Truskett

Tracer diffusion in crowded environments is central to many biological and soft matter systems, but quantitative frameworks for linking tracer motion to environmental structure remain limited. Here, we study the transport of rigid tracers…

软凝聚态物质 · 物理学 2026-05-07 Jinseok Lee , Tong Lin , Mengyang Gu , Yimin Luo

Mesh-like structures, such as mucus gel or cytoskeleton networks, are ubiquitous in biological systems. These intricate structures are composed of cross-linked, semi-flexible bio-filaments, crucial to numerous biological processes. In many…

软凝聚态物质 · 物理学 2024-01-10 Yeongjin Kim , Won Kyu Kim , Jae-Hyung Jeon

We consider one-dimensional systems comprising either active run-and-tumble particles (RTPs) or passive Brownian random walkers. These particles are either noninteracting or have hardcore exclusions. We study the dynamics of a single tracer…

统计力学 · 物理学 2022-02-11 Tirthankar Banerjee , Robert L. Jack , Michael E. Cates

30% of the DNA in E. coli bacteria is covered by proteins. Such high degree of crowding affect the dynamics of generic biological processes (e.g. gene regulation, DNA repair, protein diffusion etc.) in ways that are not yet fully…

统计力学 · 物理学 2015-06-23 Sebastian Ahlberg , Tobias Ambjörnsson , Ludvig Lizana

Based on a coarse-grained model, we carry out molecular dynamics simulations to analyze the diffusion of a small tracer particle inside a cylindrical channel whose inner wall is covered with randomly grafted short polymeric chains. We…

软凝聚态物质 · 物理学 2013-06-20 Rajarshi Chakrabarti , Stefan Kesselheim , Peter Kosovan , Christian Holm
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