相关论文: Semi-Supervised Hierarchical Drug Embedding in Hyp…

Pathology is essential for cancer diagnosis, with multiple instance learning (MIL) widely used for whole slide image (WSI) analysis. WSIs exhibit a natural hierarchy -- patches, regions, and slides -- with distinct semantic associations.…

Multilayer networks offer a powerful framework for modeling complex systems across diverse domains, effectively capturing multiple types of connections and interdependent subsystems commonly found in real world scenarios. To analyze these…

Learning good image representations that are beneficial to downstream tasks is a challenging task in computer vision. As such, a wide variety of self-supervised learning approaches have been proposed. Among them, contrastive learning has…

The computational drug repositioning aims to discover new uses for marketed drugs, which can accelerate the drug development process and play an important role in the existing drug discovery system. However, the number of validated…

The variational auto-encoder (VAE) is a popular method for learning a generative model and embeddings of the data. Many real datasets are hierarchically structured. However, traditional VAEs map data in a Euclidean latent space which cannot…

Distributed representations of medical concepts have been used to support downstream clinical tasks recently. Electronic Health Records (EHR) capture different aspects of patients' hospital encounters and serve as a rich source for…

In practice, many medical datasets have an underlying taxonomy defined over the disease label space. However, existing classification algorithms for medical diagnoses often assume semantically independent labels. In this study, we aim to…

Drug similarity has been studied to support downstream clinical tasks such as inferring novel properties of drugs (e.g. side effects, indications, interactions) from known properties. The growing availability of new types of drug features…

Hyperbolic geometry is an effective geometry for embedding hierarchical data structures. Hyperbolic learning has therefore become increasingly prominent in machine learning applications where data is hierarchically organized or governed by…

Many real-world graphs involve different types of nodes and relations between nodes, being heterogeneous by nature. The representation learning of heterogeneous graphs (HGs) embeds the rich structure and semantics of such graphs into a…

We are concerned with the discovery of hierarchical relationships from large-scale unstructured similarity scores. For this purpose, we study different models of hyperbolic space and find that learning embeddings in the Lorentz model is…

Taxonomies are valuable resources for many applications, but the limited coverage due to the expensive manual curation process hinders their general applicability. Prior works attempt to automatically expand existing taxonomies to improve…

Drug repurposing is more relevant than ever due to drug development's rising costs and the need to respond to emerging diseases quickly. Knowledge graph embedding enables drug repurposing using heterogeneous data sources combined with…

With the consolidation of deep learning in drug discovery, several novel algorithms for learning molecular representations have been proposed. Despite the interest of the community in developing new methods for learning molecular embeddings…

Hypernymy plays a fundamental role in many AI tasks like taxonomy learning, ontology learning, etc. This has motivated the development of many automatic identification methods for extracting this relation, most of which rely on word…

Traditional relational databases contain a lot of latent semantic information that have largely remained untapped due to the difficulty involved in automatically extracting such information. Recent works have proposed unsupervised machine…

Natural language processing (NLP) is utilized in a wide range of fields, where words in text are typically transformed into feature vectors called embeddings. BioConceptVec is a specific example of embeddings tailored for biology, trained…

Embedding learning transforms discrete data entities into continuous numerical representations, encoding features/properties of the entities. Despite the outstanding performance reported from different embedding learning algorithms, few…

Learning embeddings of entities and relations existing in knowledge bases allows the discovery of hidden patterns in data. In this work, we examine the geometrical space's contribution to the task of knowledge base completion. We focus on…

Graph embeddings have become a key and widely used technique within the field of graph mining, proving to be successful across a broad range of domains including social, citation, transportation and biological. Graph embedding techniques…