相关论文: Medical Applications -- Instrumentation and Diagno…
RF electronics deals with the generation, acquisition and manipulation of high-frequency signals. In particle accelerators signals of this kind are abundant, especially in the RF and beam diagnostics systems. In modern machines the…
Artificial Intelligence (AI) and Machine-Learning (ML) models have been increasingly used in medical products, such as medical device software. General considerations on the statistical aspects for the evaluation of AI/ML-enabled medical…
Raman spectroscopy provides spectral information related to the specific molecular structures of substances and has been well established as a powerful tool for studying biological tissues and diagnosing diseases. This article reviews…
Reliable estimation of treatment effects from observational data is important in many disciplines such as medicine. However, estimation is challenging when unconfoundedness as a standard assumption in the causal inference literature is…
Particle-in-Cell (PIC) simulation codes have wide applicability to first-principles modeling of multidimensional nonlinear plasma phenomena, including wake-field accelerators. This review addresses both finite difference and pseudo-spectral…
At the Centre for Proton Therapy at the Paul Scherrer Institute cancer patients are treated with a fixed beamline and in two gantries for ocular and non-ocular malignancies, respectively. For the installation of a third gantry a new patient…
It is now well established that laser plasma acceleration (LPA) is an innovative and good candidate in the beam acceleration field. Relativistic beams are indeed produced up to several GeV but their quality remains to be demonstrated in the…
The use of a ccelerators for medical applications has evolved from initial experimentation to turn-key devices commonly operating in hospitals. New applications are continuously being developed around the world, and the hadrontherapy…
Charged particle optics, the description of particle trajectories in the vicinity of some optical axis, describe the imaging properties of particle optics devices. Here, we present a complete and compact description of charged particle…
Cancer therapy using protons and heavier ions such as carbon has demonstrated advantages over other radiotherapy treatments. To bring about the next generation of clinical facilities, the requirements are likely to reduce the footprint,…
Advances in machine learning have created new opportunities to develop artificial intelligence (AI)-based clinical decision support systems using past clinical data and improve diagnosis decisions in life-threatening illnesses such breast…
Biomarkers play a central role in medicine's gradual progress towards proactive, personalized precision diagnostics and interventions. However, finding biomarkers that provide very early indicators of a change in health status, for example…
The field of Clinical-Computational Nuclear Medicine is rapidly advancing, fueled by AI, tracer kinetic modeling, radiomics, and integrated informatics. These technologies improve imaging quality, automate lesion detection, and enable…
In laser illuminated dielectric accelerators (DLA) high acceleration gradients can be achieved, due to high damage thresholds of the materials at optical frequencies. This is a necessity in developing more compact particle accelerator…
This introduction on beam position monitors (BPM) summarizes the fundamental parts of the tutorial presented at the CAS 2018 on beam instrumentation. The focus is on the signal detection and normalization, and on the principle of operation…
Radiation therapy aims to deliver the prescribed amount of dose to a tumour at the same time as sparing the surrounding tissues as much as possible. In charged particle therapy, delivering the prescribed dose is equivalent to delivering the…
Computer-aided methods have shown added value for diagnosing and predicting brain disorders and can thus support decision making in clinical care and treatment planning. This chapter will provide insight into the type of methods, their…
The medical commissioning is an important step to bring a particle gantry into clinical operation for tumour treatments. This involves the parametrization and characterization of all relevant systems including the beam delivery, the patient…
The performance and safe operation of a particle accelerator is closely connected to the transverse emittance of the beams it produces. For this reason many techniques have been developed over the years for monitoring the transverse…
Current physics models used to interpret experimental measurements of particle beams require either simplifying assumptions to be made in order to ensure analytical tractability, or black box optimization methods to perform model based…