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Structural magnetic resonance imaging (sMRI) combined with deep learning has achieved remarkable progress in the prediction and diagnosis of Alzheimer's disease (AD). Existing studies have used CNN and transformer to build a well-performing…

计算机视觉与模式识别 · 计算机科学 2025-09-11 Zheng Yang , Yanteng Zhang , Xupeng Kou , Yang Liu , Chao Ren

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

机器学习 · 计算机科学 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Purpose: Age biases have been identified as an essential factor in the diagnosis of ASD. The objective of this study was to compare the effect of different age groups in classifying ASD using morphological features (MF) and morphological…

图像与视频处理 · 电气工程与系统科学 2023-08-16 Gokul Manoj , Sandeep Singh Sengar , Jac Fredo Agastinose Ronickom

Large, open-source consortium datasets have spurred the development of new and increasingly powerful machine learning approaches in brain connectomics. However, one key question remains: are we capturing biologically relevant and…

Resting-state functional Magnetic Resonance Imaging (R-fMRI) holds the promise to reveal functional biomarkers of neuropsychiatric disorders. However, extracting such biomarkers is challenging for complex multi-faceted neuropatholo-gies,…

Autism spectrum disorder (ASD) is a highly disabling mental disease that brings significant impairments of social interaction ability to the patients, making early screening and intervention of ASD critical. With the development of the…

计算机视觉与模式识别 · 计算机科学 2025-04-08 Ruimin Ma , Ruitao Xie , Yanlin Wang , Jintao Meng , Yanjie Wei , Wenhui Xi , Yi Pan

We propose a unified optimization framework that combines neural networks with dictionary learning to model complex interactions between resting state functional MRI and behavioral data. The dictionary learning objective decomposes patient…

Accurate diagnosis of autism spectrum disorder (ASD) based on neuroimaging data has significant implications, as extracting useful information from neuroimaging data for ASD detection is challenging. Even though machine learning techniques…

机器学习 · 计算机科学 2022-06-13 Ruimin Ma , Yanlin Wang , Yanjie Wei , Yi Pan

The cross-modal synthesis between structural magnetic resonance imaging (sMRI) and functional network connectivity (FNC) is a relatively unexplored area in medical imaging, especially with respect to schizophrenia. This study employs…

图像与视频处理 · 电气工程与系统科学 2023-09-18 Yuda Bi , Anees Abrol , Jing Sui , Vince Calhoun

We present an approach to model time series data from resting state fMRI for autism spectrum disorder (ASD) severity classification. We propose to adopt kernel machines and employ graph kernels that define a kernel dot product between two…

机器学习 · 统计学 2016-12-04 Rushil Anirudh , Jayaraman J. Thiagarajan , Irene Kim , Wolfgang Polonik

The specificty and sensitivity of resting state functional MRI (rs-fMRI) measurements depend on pre-processing choices, such as the parcellation scheme used to define regions of interest (ROIs). In this study, we critically evaluate the…

计算机视觉与模式识别 · 计算机科学 2019-06-06 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert R. Sabuncu

Functional brain connectivity, as revealed through distant correlations in the signals measured by functional Magnetic Resonance Imaging (fMRI), is a promising source of biomarkers of brain pathologies. However, establishing and using…

We propose a novel matrix autoencoder to map functional connectomes from resting state fMRI (rs-fMRI) to structural connectomes from Diffusion Tensor Imaging (DTI), as guided by subject-level phenotypic measures. Our specialized autoencoder…

Although developed functional magnetic resonance imaging (fMRI) registration algorithms based on deep learning have achieved a certain degree of alignment of functional area, they underutilized fine structural information. In this paper, we…

图像与视频处理 · 电气工程与系统科学 2024-09-27 Baolong Li , Yuhu Shi , Lei Wang , Weiming Zeng , Changming Zhu

Purpose: Convolutional neural networks (CNNs) are promising in predicting treatment outcome for pediatric craniopharyngioma while the decision mechanisms are difficult to interpret. We compared the activation maps of CNN with hand crafted…

医学物理 · 物理学 2025-09-26 Wenjun Yang , Chuang Wang , Tina Davis , Jinsoo Uh , Chia-Ho Hua , Thomas E. Merchant

The estimation of causal network architectures in the brain is fundamental for understanding cognitive information processes. However, access to the dynamic processes underlying cognition is limited to indirect measurements of the hidden…

神经元与认知 · 定量生物学 2020-08-17 H. C. Ruiz-Euler , H. J. Kappen

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

神经元与认知 · 定量生物学 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

Mental disorders such as Autism Spectrum Disorders (ASD) are heterogeneous disorders that are notoriously difficult to diagnose, especially in children. The current psychiatric diagnostic process is based purely on the behavioural…

机器学习 · 计算机科学 2019-04-17 Taban Eslami , Vahid Mirjalili , Alvis Fong , Angela Laird , Fahad Saeed

Autism Spectrum Condition (ASC) is a neurodevelopmental condition characterized by impairments in communication, social interaction and restricted or repetitive behaviors. Extensive research has been conducted to identify distinctions…

定量方法 · 定量生物学 2024-05-22 F. J. Alcaide , I. A. Illan , J. Ramirez , J. M. Gorriz

Most approaches to the estimation of brain functional connectivity from the functional magnetic resonance imaging (fMRI) data rely on computing some measure of statistical dependence, or more generally, a distance between univariate…

计算机视觉与模式识别 · 计算机科学 2022-09-26 Oleg Kachan , Alexander Bernstein