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Genomics data such as RNA gene expression, methylation and micro RNA expression are valuable sources of information for various clinical predictive tasks. For example, predicting survival outcomes, cancer histology type and other patients'…

基因组学 · 定量生物学 2022-05-26 Sophie Peacock , Etai Jacob , Nikolay Burlutskiy

If the conclusion of a data analysis is sensitive to dropping very few data points, that conclusion might hinge on the particular data at hand rather than representing a more broadly applicable truth. How could we check whether this…

统计方法学 · 统计学 2024-11-12 Tin D. Nguyen , Ryan Giordano , Rachael Meager , Tamara Broderick

We present and compare multiple imputation methods for multilevel continuous and binary data where variables are systematically and sporadically missing. The methods are compared from a theoretical point of view and through an extensive…

Methods to handle missing data have been extensively explored in the context of estimation and descriptive studies, with multiple imputation being the most widely used method in clinical research. However, in the context of clinical risk…

统计方法学 · 统计学 2024-11-25 Junhui Mi , Rahul D. Tendulkar , Sarah M. C. Sittenfeld , Sujata Patil , Emily C. Zabor

In this report, we present qualitative analysis of Monte Carlo (MC) dropout method for measuring model uncertainty in neural network (NN) models. We first consider the sources of uncertainty in NNs, and briefly review Bayesian Neural…

机器学习 · 统计学 2020-07-06 Ronald Seoh

Most recent network failure diagnosis systems focused on data center networks where complex measurement systems can be deployed to derive routing information and ensure network coverage in order to achieve accurate and fast fault…

网络与互联网体系结构 · 计算机科学 2022-07-06 Yufeng Xin , Shih-Wen Fu , Anirban Mandal , Ryan Tanaka , Mats Rynge , Karan Vahi , Ewa Deelman

There is a rising need for computational models that can complementarily leverage data of different modalities while investigating associations between subjects for population-based disease analysis. Despite the success of convolutional…

图像与视频处理 · 电气工程与系统科学 2020-09-08 Yongxiang Huang , Albert C. S. Chung

Multivariate bounded discrete data arises in many fields. In the setting of dementia studies, such data is collected when individuals complete neuropsychological tests. We outline a modeling and inference procedure that can model the joint…

统计方法学 · 统计学 2026-02-10 Daniel Suen , Yen-Chi Chen

The most common strategy of imputing missing values in a table is to study either the column-column relationship or the row-row relationship of the data table, then use the relationship to impute the missing values based on the non-missing…

机器学习 · 计算机科学 2023-01-18 Fuchang Gao

Among Bayesian methods, Monte-Carlo dropout provides principled tools for evaluating the epistemic uncertainty of neural networks. Its popularity recently led to seminal works that proposed activating the dropout layers only during…

机器学习 · 计算机科学 2023-02-07 Emanuele Ledda , Giorgio Fumera , Fabio Roli

Multiple imputation (MI) has become popular for analyses with missing data in medical research. The standard implementation of MI is based on the assumption of data being missing at random (MAR). However, for missing data generated by…

统计方法学 · 统计学 2019-01-03 Tra My Pham , James R Carpenter , Tim P Morris , Angela M Wood , Irene Petersen

Multiple imputation provides an effective way to handle missing data. When several possible models are under consideration for the data, the multiple imputation is typically performed under a single-best model selected from the candidate…

统计方法学 · 统计学 2018-11-30 Gyuhyeong Goh , Jae Kwang Kim

Multiple imputation is a straightforward method for handling missing data in a principled fashion. This paper presents an overview of multiple imputation, including important theoretical results and their practical implications for…

统计方法学 · 统计学 2018-01-15 Jared S. Murray

Dropout is conventionally used during the training phase as regularization method and for quantifying uncertainty in deep learning. We propose to use dropout during training as well as inference steps, and average multiple predictions to…

图像与视频处理 · 电气工程与系统科学 2023-11-07 Mehmet Yigit Avci , Ziyu Li , Qiuyun Fan , Susie Huang , Berkin Bilgic , Qiyuan Tian

An efficient monotone data augmentation (MDA) algorithm is proposed for missing data imputation for incomplete multivariate nonnormal data that may contain variables of different types, and are modeled by a sequence of regression models…

统计方法学 · 统计学 2018-11-21 Yongqiang Tang

This paper introduces a Bayesian framework that combines Markov chain Monte Carlo (MCMC) sampling, dimensionality reduction, and neural density estimation to efficiently handle inverse problems that (i) must be solved multiple times, and…

计算工程、金融与科学 · 计算机科学 2026-02-24 Giacomo Bottacini , Matteo Torzoni , Andrea Manzoni

Multivariate time series data for real-world applications typically contain a significant amount of missing values. The dominant approach for classification with such missing values is to impute them heuristically with specific values…

机器学习 · 计算机科学 2023-08-15 SeungHyun Kim , Hyunsu Kim , EungGu Yun , Hwangrae Lee , Jaehun Lee , Juho Lee

Missing data is a fundamental challenge in data science, significantly hindering analysis and decision-making across a wide range of disciplines, including healthcare, bioinformatics, social science, e-commerce, and industrial monitoring.…

机器学习 · 统计学 2026-05-12 Jicong Fan

Monte Carlo (MC) dropout is one of the state-of-the-art approaches for uncertainty estimation in neural networks (NNs). It has been interpreted as approximately performing Bayesian inference. Based on previous work on the approximation of…

机器学习 · 计算机科学 2020-07-13 Joachim Sicking , Maram Akila , Tim Wirtz , Sebastian Houben , Asja Fischer

Missingness is a common issue for neuroimaging data, and neglecting it in downstream statistical analysis can introduce bias and lead to misguided inferential conclusions. It is therefore crucial to conduct appropriate statistical methods…

统计方法学 · 统计学 2025-03-25 Tong Lu , Chixiang Chen , Hsin-Hsiung Huang , Peter Kochunov , Elliot Hong , Shuo Chen