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Prenatal stress (PS) impacts early postnatal behavioural and cognitive development. This process of 'fetal programming' is mediated by the effects of the prenatal experience on the developing hypothalamic-pituitary-adrenal (HPA) axis and…

We review evidence supporting the role of early life programming in the susceptibility for adult neurodegenerative diseases while highlighting questions and proposing avenues for future research to advance our understanding of this…

组织与器官 · 定量生物学 2019-11-11 Paula Desplats , Ashley M. Gutierrez , Marta C. Antonelli , Martin G. Frasch

Premature birth and various pre- and peri-natal stresses can lead to a variety of brain lesions and have clearly been identified as major risk factors for neurodevelopmental disorders, with variable but multiple consequences that can…

神经元与认知 · 定量生物学 2025-05-01 Jessica Dubois , Lucie Hertz-Pannier , Sara Neumane

A major challenge in medical image analysis is the automated detection of biomarkers from neuroimaging data. Traditional approaches, often based on image registration, are limited in capturing the high variability of cortical organisation…

计算机视觉与模式识别 · 计算机科学 2022-11-17 Dániel Unyi , Bálint Gyires-Tóth

Targeted stimulation of the brain has the potential to treat mental illnesses. We propose an approach to help design the stimulation protocol by identifying electrical dynamics across many brain regions that relate to illness states. We…

机器学习 · 统计学 2023-03-09 Austin Talbot , David Dunson , Kafui Dzirasa , David Carlson

Stress is a major threat to well-being that manifests in a variety of physiological and mental symptoms. Utilising speech samples collected while the subject is undergoing an induced stress episode has recently shown promising results for…

Impact of EEG biofeedback on event-related potentials (ERPs) in attention-deficit hyperactivity (ADHD) children. Introduction: ADHD is one of the most widely spread condition of school aged children affecting 5% of children of this age.The…

神经元与认知 · 定量生物学 2011-01-31 Sophio Bakhtadze , Marine Janelidze , Nana Khachapuridze

The neonatal intensive care unit (NICU) experience is known to be one of the most crucial factors that drive preterm infant's neurodevelopmental and health outcomes. It is hypothesized that stressful early life experience of very preterm…

统计方法学 · 统计学 2019-10-10 Zhe Sun , Wanli Xu , Xiaomei Cong , Gen Li , Kun Chen

Understanding the development of adolescent behavioral and mental health outcomes requires integrating genetic predisposition, environmental exposures, and neurobiological processes over time. Here, we present a unified quantitative…

其他定量生物学 · 定量生物学 2026-05-06 Mengman Wei , Qian Peng

Electroencephalogram (EEG) provides noninvasive measures of brain activity and is found to be valuable for diagnosis of some chronic disorders. Specifically, pre-treatment EEG signals in alpha and theta frequency bands have demonstrated…

应用统计 · 统计学 2023-05-24 Bin Yang , Xingche Guo , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

Early dementia diagnosis requires biomarkers sensitive to both structural and functional brain changes. While structural neuroimaging biomarkers have progressed significantly, objective functional biomarkers of early cognitive decline…

神经元与认知 · 定量生物学 2025-04-16 Tomasz M. Rutkowski , Stanisław Narębski , Mihoko Otake-Matsuura , Tomasz Komendziński

As the global population continues to age, there is an increasing demand for ways to accurately quantify the biological processes underlying aging. Biological age, unlike chronological age, reflects an individual's physiological state,…

定量方法 · 定量生物学 2025-08-29 Jared A Kushner , Mohit Pandey , Sandeep , S Kohli

In the last decade, researchers have increasingly explored using biosensing technologies for music-based affective regulation and stress management interventions in laboratory and real-world settings. These systems -- including interactive…

人机交互 · 计算机科学 2025-07-23 Natasha Yamane , Varun Mishra , Matthew S. Goodwin

To improve the statistical power for imaging biomarker detection, we propose a latent variable-based statistical network analysis (LatentSNA) that combines brain functional connectivity with internalizing psychopathology, implementing…

统计方法学 · 统计学 2023-09-21 Selena Wang , Yunhe Liu , Wanwan Xu , Xinyuan Tian , Yize Zhao

Prenatal psychological stress affects 15-25% of pregnancies and increases risks of preterm birth, low birth weight, and adverse neurodevelopmental outcomes. Current screening relies on subjective questionnaires (PSS-10), limiting continuous…

Anxiety has become a significant health concern affecting mental and physical well-being, with state anxiety, a transient emotional response, linked to adverse cardiovascular and long-term health outcomes. This research explores the…

人机交互 · 计算机科学 2026-02-13 Jadelynn Dao , Ruixiao Liu , Sarah Solomon , Samuel Solomon

The autonomic nervous system (ANS) regulatory capacity begins before birth as the sympathetic and parasympathetic activity contributes significantly to the fetus' development. Several studies have shown how vagus nerve is involved in many…

Understanding and mitigating driving stress is vital for preventing accidents and advancing both road safety and driver well-being. While vehicles are equipped with increasingly sophisticated safety systems, many limits exist in their…

Fetal neuroinflammation and prenatal stress (PS) may contribute to lifelong neurological disabilities. Astrocytes and microglia, among the brain's non-neuronal glia cell populations, play a pivotal role in neurodevelopment, predisposition…

基因组学 · 定量生物学 2023-07-18 Martin G. Frasch , Byung-Jun Yoon , Dario-Lucas Helbing , Gal Snir , Marta C. Antonelli , Reinhard Bauer

Any person in his/her daily life activities experiences different kinds and various amounts of mental stress which has a destructive effect on their performance. Therefore, it is crucial to come up with a systematic way of stress management…

信号处理 · 电气工程与系统科学 2024-09-13 Anita Beigzadeh , Vahid Yazdnian , Kamaledin Setarehdan
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