相关论文: On physical background of nerve pulse propagation:…
In this paper mathematical models are formulated in order to simulate heat production and corresponding temperature changes which accompany the propagation of an axon potential. Based on earlier experimental results, several models are…
This paper attempts to review our studies on the propagation of signals in nerves over the past decade. The need for interdisciplinary studies is stressed that helps to understand the physical mechanisms of coupling the electrical,…
Recent studies have revealed the complex structure of nerve signals in axons. There is experimental evidence that the propagation of an electrical signal (action potential) is accompanied by mechanical and thermal effects. In this paper,…
Mathematical models describing the signals propagating in nerve fibres are described. The emphasis is on the mathematical structures of governing equations while the extremely rich physiological aspects are here not analysed. Based on…
The action potential propagating in a nerve fibre generates accompanying mechanical and thermal effects. The whole signal is therefore an ensemble which includes primary and secondary components. The primary components of a signal are the…
Early recordings of nervous conduction revealed a notable thermal signature associated with the electrical signal. The observed production and subsequent absorption of heat arise from physicochemical processes that occur at the cell…
We investigate different mechanical effects which accompany the nerve pulse propagation by using mathematical modeling. The propagation process is composed by three connected phenomena: (i) the action potential (electrical signal) which is…
It has long been known that there is no measurable heat production associated with the nerve pulse. Rather, one finds that heat production is biphasic, and a heat release during the first phase of the action potential is followed by the…
Thermogenesis is a physiological activity of releasing heat that originates from intracellular biochemical reactions. Recent experimental studies discovered that externally applied heat changes intracellular signaling locally, resulting in…
This paper deals with the mathematical modelling of signal propagation in nerve fibres. Due to the complexity of the processes where electrical, mechanical, and thermal effects are coupled, a phenomenological approach helps to build…
The in silico simulations are widely used in contemporary systems biology including the analysis of nerve pulse propagation. As known from numerous experiments, the propagation of an action potential is accompanied by mechanical and thermal…
The accepted model for nerve pulse propagation in biological membranes seems insufficient. It is restricted to dissipative electrical phenomena and considers nerve pulses exclusively as a microscopic phenomenon. A simple thermodynamic model…
The recent theoretical and experimental studies have revealed many details of signal propagation in nervous systems. In this paper an attempt is made to unify various mathematical models which describe the signal propagation in nerve…
The textbook picture of nerve activity is that of a propagating voltage pulse driven by electrical currents through ion channel proteins, which are gated by changes in voltage, temperature, pressure or by drugs. All function is directly…
Mechanical algesia is an important process for the preservation of living organisms, allowing potentially life-saving reflexes or decisions when given body parts are stressed. Yet, its various underlying mechanisms remain to be fully…
The behaviour of a di-nuclear system in the regime of strong pairing correlations is studied with the methods of statistical mechanics. It is shown that the thermal averaging is strong enough to assure the application of thermodynamical…
The extra heat generation in spin transport is usually interpreted in terms of the spin relaxation. By reformulating the heat generation rate, we found alternative current-force pairs without cross effects, which enable us to interpret the…
Using very long molecular dynamics simulation runs, temperature protocols spanning up to five orders of magnitude in time-scales are performed to investigate thermally activated structural relaxation in a model amorphous solid. The…
In the present work I analyze the factors that affect signal generation in the measurement of photothermal expansion with an atomic force microscopy probe. I discuss the general properties of the signal transduction mechanism considering…
The energy and charge fluxes carried by electrons in a two-terminal junction subjected to a random telegraph noise, produced by a single electronic defect, are analyzed. The telegraph processes are imitated by the action of a stochastic…