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Ensemble learning use multiple algorithms to obtain better predictive performance than any single one of its constituent algorithms could. With growing popularity of deep learning, researchers have started to ensemble them for various…

机器学习 · 计算机科学 2019-05-31 Ning An , Huitong Ding , Jiaoyun Yang , Rhoda Au , Ting Fang Alvin Ang

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer\{'}s disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

机器学习 · 计算机科学 2016-11-15 Ehsan Hosseini-Asl , Robert Keynto , Ayman El-Baz

This paper presents a general framework for obtaining interpretable multivariate discriminative models that allow efficient statistical inference for neuroimage analysis. The framework, termed generative discriminative machine (GDM),…

应用统计 · 统计学 2019-06-04 Erdem Varol , Aristeidis Sotiras , Ke Zeng , Christos Davatzikos

Alzheimer's disease and Frontotemporal dementia are two major types of dementia. Their accurate diagnosis and differentiation is crucial for determining specific intervention and treatment. However, differential diagnosis of these two types…

图像与视频处理 · 电气工程与系统科学 2022-06-16 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Early and accurate diagnosis of Alzheimer Disease is critical for effective clinical intervention, particularly in distinguishing it from Mild Cognitive Impairment, a prodromal stage marked by subtle structural changes. In this study, we…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Fahad Mostafa , Kannon Hossain , Hafiz Khan

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

计算机视觉与模式识别 · 计算机科学 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

Alzheimer's Disease (AD) is the most common type of dementia. In all leading countries, it is one of the primary reasons of death in senior citizens. Currently, it is diagnosed by calculating the MSME score and by the manual study of MRI…

机器学习 · 计算机科学 2019-12-11 Rishu Garg , Rekh Ram Janghel , Yogesh Rathore

Tensor classification has become increasingly crucial in statistics and machine learning, with applications spanning neuroimaging, computer vision, and recommendation systems. However, the high dimensionality of tensors presents significant…

统计方法学 · 统计学 2024-09-24 Elynn Chen , Yuefeng Han , Jiayu Li

Accurate diagnosis of Alzheimer's disease (AD) is both challenging and time consuming. With a systematic approach for early detection and diagnosis of AD, steps can be taken towards the treatment and prevention of the disease. This study…

机器学习 · 计算机科学 2022-12-12 Harshit Parmar , Eric Walden

Linear discriminant analysis (LDA) is a classical method for dimensionality reduction, where discriminant vectors are sought to project data to a lower dimensional space for optimal separability of classes. Several recent papers have…

统计计算 · 统计学 2022-03-04 Summer Atkins , Gudmundur Einarsson , Brendan Ames , Line Clemmensen

Alzheimer's disease (AD) and Lewy body dementia (LBD) present overlapping clinical features yet require distinct diagnostic strategies. While neuroimaging-based brain network analysis is promising, atlas-based representations may obscure…

神经元与认知 · 定量生物学 2026-02-25 Minheng Chen , Tong Chen , Chao Cao , Jing Zhang , Tianming Liu , Li Su , Dajiang Zhu

Normative modeling has emerged as a pivotal approach for characterizing heterogeneity and individual variance in neurodegenerative diseases, notably Alzheimer's disease(AD). One of the challenges of cortical normative modeling is the…

图像与视频处理 · 电气工程与系统科学 2026-03-13 Jianwei Zhang , Yonggang Shi

Multi-modal biological, imaging, and neuropsychological markers have demonstrated promising performance for distinguishing Alzheimer's disease (AD) patients from cognitively normal elders. However, it remains difficult to early predict when…

计算机视觉与模式识别 · 计算机科学 2019-01-08 Hongming Li , Yong Fan

The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…

图像与视频处理 · 电气工程与系统科学 2019-07-16 Kilian Hett , Vinh-Thong Ta , José V. Manjón , Pierrick Coupé

Alzheimer's disease is a neurodegenerative condition that accelerates cognitive decline relative to normal aging. It is of critical scientific importance to gain a better understanding of early disease mechanisms in the brain to facilitate…

应用统计 · 统计学 2022-01-19 D. Andrew Brown , Christopher S. McMahan , Russell T. Shinohara , Kristin A. Linn

Linear discriminant analysis (LDA) is an important classification tool in statistics and machine learning. This paper investigates the varying coefficient LDA model for dynamic data, with Bayes' discriminant direction being a function of…

统计方法学 · 统计学 2022-10-11 Yajie Bao , Yuyang Liu

The prospect of future treatment warrants the development of cost-effective screening for Alzheimer's disease (AD). A promising candidate in this regard is electroencephalography (EEG), as it is one of the most economic imaging modalities.…

信号处理 · 电气工程与系统科学 2024-05-01 Stephan Goerttler , Fei He , Min Wu

In the era of rapidly advancing medical technologies, the segmentation of medical data has become inevitable, necessitating the development of privacy preserving machine learning algorithms that can train on distributed data. Consolidating…

机器学习 · 计算机科学 2024-09-30 Paul K. Mandal

Linear Discriminant Analysis (LDA) is a well-known technique for feature extraction and dimension reduction. The performance of classical LDA, however, significantly degrades on the High Dimension Low Sample Size (HDLSS) data for the…

机器学习 · 计算机科学 2023-03-09 Sijia Yang , Haoyi Xiong , Kaibo Xu , Licheng Wang , Jiang Bian , Zeyi Sun

Machine learning (ML) has shown great promise for revolutionizing a number of areas, including healthcare. However, it is also facing a reproducibility crisis, especially in medicine. ML models that are carefully constructed from and…

机器学习 · 计算机科学 2024-09-16 Rongguang Wang , Guray Erus , Pratik Chaudhari , Christos Davatzikos