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Data collected in clinical trials are often composed of multiple types of variables. For example, laboratory measurements and vital signs are longitudinal data of continuous or categorical variables, adverse events may be recurrent events,…

统计方法学 · 统计学 2023-01-12 Tuo Wang , Rachel Zilinskas , Ying Li , Yongming Qu

Evaluating treatment effects is critical in clinical trials but sometimes involves lengthy, invasive, or costly follow-up procedures. In these cases, surrogate markers, which provide intermediate measures of the long-term treatment effect,…

统计方法学 · 统计学 2026-03-24 Sarah C. Lotspeich , P. D. Anh. Nguyen , Layla Parast

Handling missing data in time series classification remains a significant challenge in various domains. Traditional methods often rely on imputation, which may introduce bias or fail to capture the underlying temporal dynamics. In this…

机器学习 · 计算机科学 2026-04-03 YongKyung Oh , Dong-Young Lim , Sungil Kim , Alex Bui

In many application settings, the data have missing entries which make analysis challenging. An abundant literature addresses missing values in an inferential framework: estimating parameters and their variance from incomplete tables. Here,…

机器学习 · 统计学 2024-03-22 Julie Josse , Jacob M. Chen , Nicolas Prost , Erwan Scornet , Gaël Varoquaux

We carry out ANOVA comparisons of multiple treatments for longitudinal studies with missing values. The treatment effects are modeled semiparametrically via a partially linear regression which is flexible in quantifying the time effects of…

统计理论 · 数学 2012-11-14 Song Xi Chen , Ping-Shou Zhong

We present a framework for generating multiple imputations for continuous data when the missing data mechanism is unknown. Imputations are generated from more than one imputation model in order to incorporate uncertainty regarding the…

应用统计 · 统计学 2013-01-14 Juned Siddique , Ofer Harel , Catherine M. Crespi

Heterogeneous but complementary sources of data provide an unprecedented opportunity for developing accurate statistical models of systems. Although the existing methods have shown promising results, they are mostly applicable to situations…

应用统计 · 统计学 2020-08-18 Feng Wang , Mostafa Reisi Gahrooei , Zhen Zhong , Tao Tang , Jianjun Shi

Robot task planning from high-level instructions is an important step towards deploying fully autonomous robot systems in the service sector. Three key aspects of robot task planning present challenges yet to be resolved simultaneously,…

机器人学 · 计算机科学 2025-07-29 Weixiao Zhan , Qiyue Dong , Eduardo Sebastián , Nikolay Atanasov

There is an emerging trend in the reinforcement learning for healthcare literature. In order to prepare longitudinal, irregularly sampled, clinical datasets for reinforcement learning algorithms, many researchers will resample the time…

机器学习 · 计算机科学 2019-11-19 Scott L. Fleming , Kuhan Jeyapragasan , Tony Duan , Daisy Ding , Saurabh Gombar , Nigam Shah , Emma Brunskill

Attrition in survey and field experiments presents a challenge for social science research. Common approaches to deal with this problem -- such as complete case analysis, multiple imputation, and weighting methods -- rely on strong…

统计方法学 · 统计学 2026-04-13 Xiangyu Song

Nonignorable missing data, where the probability of missingness depends on unobserved values, presents a significant challenge in statistical analysis. Traditional methods often rely on strong parametric assumptions that are difficult to…

统计方法学 · 统计学 2025-09-19 Yujie Zhao

Longitudinal electronic health record (EHR) data offer opportunities to study biomarker trajectories; however, association estimates-the primary inferential target-from standard models designed for regular observation times may be biased by…

统计方法学 · 统计学 2026-02-18 Cheng-Han Yang , Xu Shi , Bhramar Mukherjee

Many real-world networks are known to exhibit facts that counter our knowledge prescribed by the theories on network creation and communication patterns. A common prerequisite in network analysis is that information on nodes and links will…

物理与社会 · 物理学 2018-04-03 Guy Kelman , Eran Manes , Marco Lamieri , David Breé

We introduce a new nonparametric framework for classification problems in the presence of missing data. The key aspect of our framework is that the regression function decomposes into an anova-type sum of orthogonal functions, of which some…

统计理论 · 数学 2024-05-06 Torben Sell , Thomas B. Berrett , Timothy I. Cannings

In applications such as object tracking, time-series data inevitably carry missing observations. Following the success of deep learning-based models for various sequence learning tasks, these models increasingly replace classic approaches…

计算机视觉与模式识别 · 计算机科学 2021-12-03 Stefan Becker , Ronny Hug , Wolfgang Hübner , Michael Arens , Brendan T. Morris

This paper reviews recent advances in missing data research using graphical models to represent multivariate dependencies. We first examine the limitations of traditional frameworks from three different perspectives: \textit{transparency,…

统计方法学 · 统计学 2019-11-15 Karthika Mohan , Judea Pearl

Joint modeling technique is a recent advancement in effectively analyzing the longitudinal history of patients with the occurrence of an event of interest attached to it. This procedure is successfully implemented in biomarker studies to…

统计方法学 · 统计学 2021-01-08 Gajendra K. Vishwakarma , Atanu Bhattacharjee , Souvik Banerjee

Observational studies provide invaluable opportunities to draw causal inference, but they may suffer from biases due to pretreatment difference between treated and control units. Matching is a popular approach to reduce observed covariate…

统计方法学 · 统计学 2025-09-17 Xinran Li

We study problems with multiple missing covariates and partially observed responses. We develop a new framework to handle complex missing covariate scenarios via inverse probability weighting, regression adjustment, and a multiply-robust…

统计方法学 · 统计学 2021-11-04 Daniel Suen , Yen-Chi Chen

Machine learning techniques have been developed to learn from complete data. When missing values exist in a dataset, the incomplete data should be preprocessed separately by removing data points with missing values or imputation. In this…

机器学习 · 计算机科学 2020-12-25 Hadi A. Khorshidi , Michael Kirley , Uwe Aickelin