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In many scientific and engineering domains, physical experiments are often costly, non-replicable, or time-consuming. The Kennedy and O'Hagan (KOH) model framework has become a widely used approach for combining simulator runs with limited…

统计计算 · 统计学 2026-03-18 Hao Zhu , Markus Hainy

The state-of-the-art methods for estimating high-dimensional covariance matrices all shrink the eigenvalues of the sample covariance matrix towards a data-insensitive shrinkage target. The underlying shrinkage transformation is either…

机器学习 · 统计学 2025-11-25 Man-Chung Yue , Yves Rychener , Daniel Kuhn , Viet Anh Nguyen

We introduce a novel Bayesian approach for both covariate selection and sparse precision matrix estimation in the context of high-dimensional Gaussian graphical models involving multiple responses. Our approach provides a sparse estimation…

统计方法学 · 统计学 2024-09-25 Anwesha Chakravarti , Naveen N. Narishetty , Feng Liang

Materials design can be cast as an optimization problem with the goal of achieving desired properties, by varying material composition, microstructure morphology, and processing conditions. Existence of both qualitative and quantitative…

In experimental design, we are given $n$ vectors in $d$ dimensions, and our goal is to select $k\ll n$ of them to perform expensive measurements, e.g., to obtain labels/responses, for a linear regression task. Many statistical criteria have…

机器学习 · 计算机科学 2019-06-11 Michał Dereziński , Feynman Liang , Michael W. Mahoney

Gaussian graphical models are used for determining conditional relationships between variables. This is accomplished by identifying off-diagonal elements in the inverse-covariance matrix that are non-zero. When the ratio of variables (p) to…

应用统计 · 统计学 2018-08-07 Donald R. Williams , Juho Piironen , Aki Vehtari , Philippe Rast

We formalize the problem of contextual optimization through the lens of Bayesian experimental design and propose CO-BED -- a general, model-agnostic framework for designing contextual experiments using information-theoretic principles.…

机器学习 · 统计学 2023-07-20 Desi R. Ivanova , Joel Jennings , Tom Rainforth , Cheng Zhang , Adam Foster

This paper considers the problem of constructing optimal discriminating experimental designs for competing regression models on the basis of the T-optimality criterion introduced by Atkinson and Fedorov [Biometrika 62 (1975) 57-70].…

统计理论 · 数学 2014-01-30 Holger Dette , Viatcheslav B. Melas , Petr Shpilev

In conventional randomized controlled trials, adjustment for baseline values of covariates known to be at least moderately associated with the outcome increases the power of the trial. Recent work has shown particular benefit for more…

统计方法学 · 统计学 2023-11-27 James Willard , Shirin Golchi , Erica EM Moodie

This manuscript is concerned with relating two approaches that can be used to explore complex dependence structures between categorical variables, namely Bayesian partitioning of the covariate space incorporating a variable selection…

统计方法学 · 统计学 2016-01-06 Michail Papathomas , Sylvia Richardson

Complex engineered systems require coordinated design choices across heterogeneous components under multiple conflicting objectives and uncertain specifications. Monotone co-design provides a compositional framework for such problems by…

最优化与控制 · 数学 2026-03-20 Yujun Huang , Gioele Zardini

We study the optimal sample complexity of variable selection in linear regression under general design covariance, and show that subset selection is optimal while under standard complexity assumptions, efficient algorithms for this problem…

统计理论 · 数学 2025-10-07 Ming Gao , Bryon Aragam

For many important problems the quantity of interest is an unknown function of the parameters, which is a random vector with known statistics. Since the dependence of the output on this random vector is unknown, the challenge is to identify…

机器学习 · 统计学 2021-04-28 Themistoklis P. Sapsis

The construction of decision-theoretic Bayesian designs for realistically-complex nonlinear models is computationally challenging, as it requires the optimization of analytically intractable expected utility functions over high-dimensional…

统计方法学 · 统计学 2016-07-01 Antony Overstall , David Woods

An efficient algorithm for the determination of Bayesian optimal discriminating designs for competing regression models is developed, where the main focus is on models with general distributional assumptions beyond the "classical" case of…

统计计算 · 统计学 2015-08-04 Holger Dette , Roman Guchenko , Viatcheslav B. Melas

This paper considers an optimization problem for a dynamical system whose evolution depends on a collection of binary decision variables. We develop scalable approximation algorithms with provable suboptimality bounds to provide…

最优化与控制 · 数学 2016-10-31 Insoon Yang , Samuel A. Burden , Ram Rajagopal , S. Shankar Sastry , Claire J. Tomlin

Implicit stochastic models, where the data-generation distribution is intractable but sampling is possible, are ubiquitous in the natural sciences. The models typically have free parameters that need to be inferred from data collected in…

机器学习 · 统计学 2020-08-17 Steven Kleinegesse , Michael U. Gutmann

Optimal experimental design (OED) plays an important role in the problem of identifying uncertainty with limited experimental data. In many applications, we seek to minimize the uncertainty of a predicted quantity of interest (QoI) based on…

最优化与控制 · 数学 2022-01-06 Keyi Wu , Peng Chen , Omar Ghattas

We consider the problem of efficient statistical inference for comparing two regression curves estimated from two samples of dependent measurements. Based on a representation of the best pair of linear unbiased estimators in continuous time…

统计方法学 · 统计学 2016-01-29 Holger Dette , Kirsten Schorning , Maria Konstantinou

Bayesian optimal experimental design is a principled framework for conducting experiments that leverages Bayesian inference to quantify how much information one can expect to gain from selecting a certain design. However, accurate Bayesian…

机器学习 · 统计学 2025-11-12 Yasir Zubayr Barlas , Sabina J. Sloman , Samuel Kaski