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Within a short period of time, COVID-19 grew into a world-wide pandemic. Transmission by pre-symptomatic and asymptomatic viral carriers rendered intervention and containment of the disease extremely challenging. Based on reported infection…

This article considers the minimization of the total number of infected individuals over the course of an epidemic in which the rate of infectious contacts can be reduced by time-dependent nonpharmaceutical interventions. The societal and…

最优化与控制 · 数学 2023-03-16 Tom Britton , Lasse Leskelä

Metapopulation epidemic models help capture the spatial dimension of infectious disease spread by dividing heterogeneous populations into separate but interconnected communities, represented by nodes in a network. In the event of an…

种群与进化 · 定量生物学 2025-02-21 Henrik Zunker , Philipp Dönges , Patrick Lenz , Seba Contreras , Martin J. Kühn

As a common strategy of contagious disease containment, lockdowns will inevitably weaken the economy. The ongoing COVID-19 pandemic underscores the trade-off arising from public health and economic cost. An optimal lockdown policy to…

最优化与控制 · 数学 2022-01-26 Qianqian Ma , Yang-Yu Liu , Alex Olshevsky

In this paper, we propose a dynamical model to describe the transmission of COVID-19, which is spreading in China and many other countries. To avoid a larger outbreak in the worldwide, Chinese government carried out a series of strong…

种群与进化 · 定量生物学 2020-03-09 Jiwei Jia , Jian Ding , Siyu Liu , Guidong Liao , Jingzhi Li , Ben Duan , Guoqing Wang , Ran Zhang

The global pandemic of the 2019-nCov requires the evaluation of policy interventions to mitigate future social and economic costs of quarantine measures worldwide. We propose an epidemiological model for forecasting and policy evaluation…

应用统计 · 统计学 2020-10-30 Philip Nadler , Shuo Wang , Rossella Arcucci , Xian Yang , Yike Guo

Coronavirus disease (COVID-19) which is caused by SARS-COV2 has become a pandemic. This disease is highly infectious and potentially fatal, causing a global public health concern. To contain the spread of COVID-19, governments are adopting…

物理与社会 · 物理学 2020-06-22 Sayantari Ghosh , Saumik Bhattacharya

Background: Recently developed techniques to study the spread of infectious diseases through networks make assumptions that the initial proportion infected is infinitesimal and the population behavior is static throughout the epidemic. The…

种群与进化 · 定量生物学 2012-08-17 Joel C. Miller

In this paper we develop a predictive model for the spread of COVID-19 infection at a provincial (i.e. EU NUTS-3) level in Italy by using official data from the Italian Ministry of Health integrated with data extracted from daily official…

The current global health emergency triggered by the pandemic COVID-19 is one of the greatest challenges mankind face in this generation. Computational simulations have played an important role to predict the development of the current…

种群与进化 · 定量生物学 2020-06-11 Kok Yew Ng , Meei Mei Gui

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

应用统计 · 统计学 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

This paper presents the assessment of time-dependent national-level restrictions and control actions and their effects in fighting the COVID-19 pandemic. By analysing the transmission dynamics during the first wave of COVID-19 in the…

种群与进化 · 定量生物学 2021-02-04 Ton Duc Do , Meei Mei Gui , Kok Yew Ng

Compartmental models are widely adopted to describe and predict the spreading of infectious diseases. The unknown parameters of such models need to be estimated from the data. Furthermore, when some of the model variables are not…

物理与社会 · 物理学 2021-01-18 Luca Gallo , Mattia Frasca , Vito Latora , Giovanni Russo

In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive political, social and pharmaceutical measures. Optimal control…

最优化与控制 · 数学 2022-11-01 Giovanni Ziarelli , Luca Dede' , Nicola Parolini , Marco Verani , Alfio Quarteroni

Different countries -- and sometimes different regions within the same countries -- have adopted different strategies in trying to contain the ongoing COVID-19 epidemic; these mix in variable parts social confinement, early detection and…

种群与进化 · 定量生物学 2020-07-17 Giuseppe Gaeta

The recent COVID-19 pandemic has promoted vigorous scientific activity in an effort to understand, advice and control the pandemic. Data is now freely available at a staggering rate worldwide. Unfortunately, this unprecedented level of…

应用统计 · 统计学 2024-01-31 Yuansan Liu , Saransh Srivastava , Zuo Huang , Felisa J. Vázquez-Abad

We consider here an extended SIR model, including several features of the recent COVID-19 outbreak: in particular the infected and recovered individuals can either be detected (+) or undetected (-) and we also integrate an intensive care…

种群与进化 · 定量生物学 2020-05-25 Arthur Charpentier , Romuald Elie , Mathieu Laurière , Viet Chi Tran

Epidemic outbreaks pose significant challenges to public health and socio-economic stability, necessitating a comprehensive understanding of disease transmission dynamics and effective control strategies. This article discusses the…

物理与社会 · 物理学 2023-10-20 Sourin Chatterjee , Ahad N. Zehmakan , Sujay Rastogi

A fractional-order compartmental model was recently used to describe real data of the first wave of the COVID-19 pandemic in Portugal [Chaos Solitons Fractals 144 (2021), Art. 110652]. Here, we modify that model in order to correct time…

最优化与控制 · 数学 2022-04-12 Silverio Rosa , Delfim F. M. Torres

Capturing the structure of a population and characterising contacts within the population are key to reliable projections of infectious disease. Two main elements of population structure -- contact heterogeneity and age -- have been…

物理与社会 · 物理学 2025-03-17 Luke Murray Kearney , Emma L. Davis , Matt J. Keeling