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Purpose: (1) To develop a deep learning algorithm to identify major tissue structures of the optic nerve head (ONH) in 3D optical coherence tomography (OCT) scans; (2) to exploit such information to robustly differentiate among healthy,…

Dynamic imaging is critical for understanding and visualizing dynamic biological processes in medicine and cell biology. These applications often encounter the challenge of a limited amount of time series data and time points, which hinders…

图像与视频处理 · 电气工程与系统科学 2025-05-20 Sven Dummer , Puru Vaish , Christoph Brune

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

医学物理 · 物理学 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan

The automatic detection and localization of anatomical features in retinal imaging data are relevant for many aspects. In this work, we follow a data-centric approach to optimize classifier training for optic nerve head detection and…

Optical coherence tomography (OCT) uses low-coherence reflectometry to obtain cross-sectional images of inhomogeneous media, such as biological tissue. OCT is particularly useful in the biomedical ea, since the imaging can be performed…

医学物理 · 物理学 2018-03-01 Takahisa Mitsui , Kenichiro Aoki

Purpose: The integration of multimodal imaging into operating rooms paves the way for comprehensive surgical scene understanding. In ophthalmic surgery, by now, two complementary imaging modalities are available: operating microscope (OPMI)…

计算机视觉与模式识别 · 计算机科学 2026-03-27 Nikolo Rohrmoser , Ghazal Ghazaei , Michael Sommersperger , Nassir Navab

Computational corrections of defocus and aberrations in optical coherence tomography (OCT) offers a promising approach to realize high-resolution imaging with deep imaging depth, but without additional high hardware costs. However, these…

光学 · 物理学 2025-10-28 Shuichi Makita , Naoki Fukutake , Lida Zhu , Yoshiaki Yasuno

Retinal optical coherence tomography (OCT) images provide crucial insights into the health of the posterior ocular segment. Therefore, the advancement of automated image analysis methods is imperative to equip clinicians and researchers…

图像与视频处理 · 电气工程与系统科学 2024-02-16 Jiahao Wang , Hong Peng , Shengchao Chen , Sufen Ren

Dynamic optical coherence tomography (DOCT) enables label-free functional imaging by capturing temporal OCT signal variations caused by intracellular and intratissue motions. However, the relationship between DOCT signals and the sample…

Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for early diagnosis of retinal diseases. In…

计算机视觉与模式识别 · 计算机科学 2019-05-28 Peyman Gholami , Priyanka Roy , Mohana Kuppuswamy Parthasarathy , Vasudevan Lakshminarayanan

With the introduction of spectral-domain optical coherence tomography (SDOCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, there is a critical need…

计算机视觉与模式识别 · 计算机科学 2015-08-06 Yankui Sun , Tian Zhang , Yue Zhao , Yufan He

Optical coherence tomography (OCT) is a non-invasive imaging technique that can produce images of the eye at the microscopic level. OCT image segmentation to localise retinal layer boundaries is a fundamental procedure for diagnosing and…

计算机视觉与模式识别 · 计算机科学 2016-09-09 Jinming Duan , Christopher Tench , Irene Gottlob , Frank Proudlock , Li Bai

Reducing the bit-depth is an effective approach to lower the cost of optical coherence tomography (OCT) systems and increase the transmission efficiency in data acquisition and telemedicine. However, a low bit-depth will lead to the…

图像与视频处理 · 电气工程与系统科学 2021-02-03 Qiangjiang Hao , Kang Zhou , Jianlong Yang , Liyang Fang , Zhengjie Chai , Yuhui Ma , Yan Hu , Shenghua Gao , Jiang Liu

Relatively abundant availability of medical imaging data has provided significant support in the development and testing of Neural Network based image processing methods. Clinicians often face issues in selecting suitable image processing…

图像与视频处理 · 电气工程与系统科学 2021-09-10 Mayank Goswami

Optical coherence tomography (OCT) helps ophthalmologists assess macular edema, accumulation of fluids, and lesions at microscopic resolution. Quantification of retinal fluids is necessary for OCT-guided treatment management, which relies…

图像与视频处理 · 电气工程与系统科学 2022-12-15 Reza Rasti , Armin Biglari , Mohammad Rezapourian , Ziyun Yang , Sina Farsiu

This study introduces a groundbreaking optical coherence tomography (OCT) imaging system dedicated for high-throughput screening applications using ex vivo tissue culture. Leveraging OCT's non-invasive, high-resolution capabilities, the…

Our objective is to evaluate the efficacy of methods that use deep learning (DL) for the automatic fine-grained segmentation of optical coherence tomography (OCT) images of the retina. OCT images from 10 patients with mild non-proliferative…

计算机视觉与模式识别 · 计算机科学 2018-01-31 Mike Pekala , Neil Joshi , David E. Freund , Neil M. Bressler , Delia Cabrera DeBuc , Philippe M Burlina

Optical coherence tomography (OCT) is an important interferometric diagnostic technique which provides cross-sectional views of the subsurface microstructure of biological tissues. However, the imaging quality of high-speed OCT is limited…

计算机视觉与模式识别 · 计算机科学 2015-03-13 Liheng Bian , Jinli Suo , Feng Chen , Qionghai Dai

Automated surface segmentation of retinal layer is important and challenging in analyzing optical coherence tomography (OCT). Recently, many deep learning based methods have been developed for this task and yield remarkable performance.…

图像与视频处理 · 电气工程与系统科学 2022-03-07 Hong Liu , Dong Wei , Donghuan Lu , Yuexiang Li , Kai Ma , Liansheng Wang , Yefeng Zheng

Mechanical properties of tissue provide valuable information for identifying lesions. One approach to obtain quantitative estimates of elastic properties is shear wave elastography with optical coherence elastography (OCE). However, given…

图像与视频处理 · 电气工程与系统科学 2020-04-30 Maximilian Neidhardt , Marcel Bengs , Sarah Latus , Matthias Schlüter , Thore Saathoff , Alexander Schlaefer