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This article presents a highly efficient optimal control algorithm and policies for lyophilization (also known as freeze drying). The optimal solutions and control policies are derived using an extended version of the simulation-based…

最优化与控制 · 数学 2025-09-16 Prakitr Srisuma , Richard D. Braatz

This paper considers an optimization problem for a dynamical system whose evolution depends on a collection of binary decision variables. We develop scalable approximation algorithms with provable suboptimality bounds to provide…

最优化与控制 · 数学 2016-10-31 Insoon Yang , Samuel A. Burden , Ram Rajagopal , S. Shankar Sastry , Claire J. Tomlin

Accurate representation of observed driving behavior is critical for effectively evaluating safety and performance interventions in simulation modeling. In this study, we implement and evaluate a safety-based Optimal Velocity Model (OVM) to…

机器人学 · 计算机科学 2022-10-18 Awad Abdelhalim , Montasir Abbas

The paper addresses an optimal control problem for a perturbed sweeping process of the rate-independent hysteresis type described by a controlled "play and stop" operator with separately controlled perturbations. This problem can be reduced…

最优化与控制 · 数学 2015-12-01 Tan H. Cao , Boris S. Mordukhovich

Multiobjective simulation optimization (MOSO) problems are optimization problems with multiple conflicting objectives, where evaluation of at least one of the objectives depends on a black-box numerical code or real-world experiment, which…

最优化与控制 · 数学 2025-01-13 Tyler H. Chang , Stefan M. Wild

Black-box optimization (BBO) has a broad range of applications, including automatic machine learning, engineering, physics, and experimental design. However, it remains a challenge for users to apply BBO methods to their problems at hand…

Optimal control is a central problem in quantum thermodynamics. When minimizing dissipated work and work fluctuations defined via the two-point measurement scheme in open quantum systems, existing approaches largely focus on the rapid- and…

量子物理 · 物理学 2026-04-08 Yuki Kurokawa , Yoshihiko Hasegawa

Optimization of expensive computer models with the help of Gaussian process emulators in now commonplace. However, when several (competing) objectives are considered, choosing an appropriate sampling strategy remains an open question. We…

最优化与控制 · 数学 2013-10-03 Victor Picheny

We present a novel reduced-order Model (ROM) that leverages optimal transport (OT) theory and displacement interpolation to enhance the representation of nonlinear dynamics in complex systems. While traditional ROM techniques face…

This paper addresses the challenge of efficiently solving the optimal power flow problem in real-time electricity markets. The proposed solution, named Physics-Informed Market-Aware Active Set learning OPF (PIMA-AS-OPF), leverages physical…

The dramatic increase of observational data across industries provides unparalleled opportunities for data-driven decision making and management, including the manufacturing industry. In the context of production, data-driven approaches can…

最优化与控制 · 数学 2018-01-09 Najibesadat Sadati , Ratna Babu Chinnam , Milad Zafar Nezhad

Proximal Policy Optimization (PPO) is a highly popular model-free reinforcement learning (RL) approach. However, we observe that in a continuous action space, PPO can prematurely shrink the exploration variance, which leads to slow progress…

机器学习 · 计算机科学 2020-11-04 Perttu Hämäläinen , Amin Babadi , Xiaoxiao Ma , Jaakko Lehtinen

In this paper, we focus on a method based on optimal control to address the optimization problem. The objective is to find the optimal solution that minimizes the objective function. We transform the optimization problem into optimal…

最优化与控制 · 数学 2023-09-12 Yeming Xu , Ziyuan Guo , Hongxia Wang , Huanshui Zhang

In this paper we consider a method of solving optimal stopping problems in discrete and continuous time based on their dual representation. A novel and generic simulation-based optimization algorithm not involving nested simulations is…

概率论 · 数学 2013-09-10 Denis Belomestny

In many areas of systems biology, including virology, pharmacokinetics, and population biology, dynamical systems are commonly used to describe biological processes. These systems can be characterized by estimating their parameters from…

机器学习 · 统计学 2025-11-11 Tuan Minh Ha , Binh Thanh Nguyen , Lam Si Tung Ho

The main feature of the Dynamic Multi-objective Optimization Problems (DMOPs) is that optimization objective functions will change with times or environments. One of the promising approaches for solving the DMOPs is reusing the obtained…

神经与进化计算 · 计算机科学 2019-10-22 Weizhen Hu , Min Jiang , Xing Gao , Kay Chen Tan , Yiu-ming Cheung

Predicting the response of an observed system to a known input is a fruitful first step to accurately control the system's dynamics. Despite the recent advances in fully data-driven algorithms, the most interpretable way to reach this goal…

We propose a multi-criteria Composite Index Method (CIM) to compare the performance of alternative approaches to solving an optimization problem. The CIM is convenient in those situations when neither approach dominates the other when…

最优化与控制 · 数学 2022-12-29 Yulan Bai , Eli Olinick

Ordinary differential equations (ODEs) are widely used to model biological, (bio-)chemical and technical processes. The parameters of these ODEs are often estimated from experimental data using ODE-constrained optimisation. This article…

最优化与控制 · 数学 2015-11-06 Anna Fiedler , Fabian J. Theis , Jan Hasenauer

In sequence generation task, many works use policy gradient for model optimization to tackle the intractable backpropagation issue when maximizing the non-differentiable evaluation metrics or fooling the discriminator in adversarial…

计算与语言 · 计算机科学 2018-08-27 Yi-Lin Tuan , Jinzhi Zhang , Yujia Li , Hung-yi Lee