相关论文: Quantum correlations overcome the photodamage limi…
Much of our progress in understanding microscale biology has been powered by advances in microscopy. For instance, super-resolution microscopes allow the observation of biological structures at near-atomic-scale resolution, while…
Ultrafast lasers have become one of the most powerful tools in coherent nonlinear optical spectroscopy. Short pulses enable direct observation of fast molecular dynamics, whereas broad spectral bandwidth offers ways of controlling nonlinear…
Nonlinear optical processes are used in biological microscopy to surpass the diffraction limit on resolution, image deeper into brain tissues, and identify biomolecules without exogenous labels. These techniques typically require high…
Classical linear optics posits that at sufficiently low intensities, light propagation in dielectric media is governed solely by their linear susceptibilities. Here, we demonstrate a departure from this paradigm in high-Q microresonators,…
Stimulated Raman scattering (SRS) microscopy is a powerful label-free imaging technique that probes the vibrational response of chemicals with high specificity and sensitivity. High-power, quantum-enhanced SRS microscopes have been recently…
Light and matter share fundamental statistical properties, yet the experimental probes of quantum optics and many-body physics have largely evolved along separate trajectories. While many-body physics explores emergent collective phenomena,…
Quantum optics has driven major advances in our ability to generate and detect correlations between individual photons. Its principles are now increasingly translated into nanoscale characterization techniques, enhancing spectroscopy,…
Recovering both amplitude and phase information from a system is a fundamental goal of optical imaging. At the same time, it is crucial to operate at low photon doses to avoid altering the sample, particularly in biological applications.…
We develop an ultrafast frequency-resolved Raman spectroscopy with entangled photons for polyatomic molecules in condensed phases, to probe the electronic and vibrational coherences. Using quantum correlation between the photons, the signal…
Correlated photon pairs, carrying strong quantum correlations, have been harnessed to bring quantum advantages to various fields from biological imaging to range finding. Such inherent non-classical properties support extracting more valid…
The last two decades experimentally affirmed the quantum nature of free electron wavepackets by the rapid development of transmission electron microscopes into ultrafast, quantum-coherent systems. In particular, ultrafast electron pulses…
Novel imaging techniques utilizing nondegenerate, correlated photon pairs sparked intense interest during the last couple of years among scientists of the quantum optics community and beyond. It is a key property of such "ghost imaging" or…
Nonlinear optical microscopy allows rapid high-resolution microscopy with image contrast generated from intrinsic properties of the sample. Established modalities such as multiphoton excited fluorescence and second/third-harmonic generation…
Quantum imaging is an ever expanding research field, in which the aim is to exploit the quantum nature of light to enhance image reconstruction capabilities. Despite a number of successful demonstrations for quantum imaging, quantum…
Despite advances in low-light level detection, single-photon methods such as photon correlation have rarely been used in the context of imaging. The few demonstrations, for example of sub-diffraction limited imaging utilizing quantum…
Entangled photons have the remarkable ability to be more sensitive to signal and less sensitive to noise than classical light. Joint photons can sample an object collectively, resulting in faster phase accumulation and higher spatial…
Entangled biphoton sources exhibit nonclassical characteristics and have been applied to imaging techniques such as ghost imaging, quantum holography, and quantum optical coherence tomography. The development of wide-field quantum imaging…
We report both sub-diffraction-limited quantum metrology and quantum enhanced spatial resolution for the first time in a biological context. Nanoparticles are tracked with quantum correlated light as they diffuse through an extended region…
Quantum sensing exploits quantum phenomena to enhance the detection and estimation of classical parameters of physical systems and biological entities, particularly so as to overcome the inefficiencies of its classical counterparts. A…
We describe a detector that measures the mutual coherence of two optical fields directly using quantum interference, free from photon noise of the individual irradiances. Our approach utilizes Raman transition in an atomic system where the…