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Convolutional neural networks have led to significant breakthroughs in the domain of medical image analysis. However, the task of breast cancer segmentation in whole-slide images (WSIs) is still underexplored. WSIs are large…

计算机视觉与模式识别 · 计算机科学 2018-07-31 Nanqing Dong , Michael Kampffmeyer , Xiaodan Liang , Zeya Wang , Wei Dai , Eric P. Xing

Whole slide image (WSI) analysis in digital pathology presents unique challenges due to the gigapixel resolution of WSIs and the scarcity of dense supervision signals. While Multiple Instance Learning (MIL) is a natural fit for slide-level…

计算机视觉与模式识别 · 计算机科学 2025-08-21 Sofiène Boutaj , Marin Scalbert , Pierre Marza , Florent Couzinie-Devy , Maria Vakalopoulou , Stergios Christodoulidis

Deploying digital pathology models across medical centers is challenging due to distribution shifts. Recent advances in domain generalization improve model transferability in terms of aggregated performance measured by the Area Under Curve…

计算机视觉与模式识别 · 计算机科学 2025-07-25 Arthur Pignet , John Klein , Genevieve Robin , Antoine Olivier

Whole Slide Images (WSIs) or histopathology images are used in digital pathology. WSIs pose great challenges to deep learning models for clinical diagnosis, owing to their size and lack of pixel-level annotations. With the recent…

Whole-Slide Images (WSIs) have revolutionized medical analysis by presenting high-resolution images of the whole tissue slide. Despite avoiding the physical storage of the slides, WSIs require considerable data volume, which makes the…

图像与视频处理 · 电气工程与系统科学 2025-03-25 Yu Mao , Jun Wang , Nan Guan , Chun Jason Xue

Advancement in digital pathology and artificial intelligence has enabled deep learning-based computer vision techniques for automated disease diagnosis and prognosis. However, WSIs present unique computational and algorithmic challenges.…

计算机视觉与模式识别 · 计算机科学 2021-06-15 Yash Sharma , Lubaina Ehsan , Sana Syed , Donald E. Brown

While Multiple Instance Learning (MIL) has shown promising results in digital Pathology Whole Slide Image (WSI) classification, such a paradigm still faces performance and generalization problems due to challenges in high computational…

计算机视觉与模式识别 · 计算机科学 2023-03-16 Honglin Li , Chenglu Zhu , Yunlong Zhang , Yuxuan Sun , Zhongyi Shui , Wenwei Kuang , Sunyi Zheng , Lin Yang

Digital pathology has attracted significant attention in recent years. Analysis of Whole Slide Images (WSIs) is challenging because they are very large, i.e., of Giga-pixel resolution. Identifying Regions of Interest (ROIs) is the first…

图像与视频处理 · 电气工程与系统科学 2020-09-21 A Nugaliyadde , Kok Wai Wong , Jeremy Parry , Ferdous Sohel , Hamid Laga , Upeka V. Somaratne , Chris Yeomans , Orchid Foster

The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Current staining and advanced labeling methods are often…

Whole slide images are the foundation of digital pathology for the diagnosis and treatment of carcinomas. Writing pathology reports is laborious and error-prone for inexperienced pathologists. To reduce the workload and improve clinical…

计算机视觉与模式识别 · 计算机科学 2024-06-28 Pingyi Chen , Honglin Li , Chenglu Zhu , Sunyi Zheng , Zhongyi Shui , Lin Yang

Whole slide image (WSI) classification is a critical task in computational pathology, requiring the processing of gigapixel-sized images, which is challenging for current deep-learning methods. Current state of the art methods are based on…

计算机视觉与模式识别 · 计算机科学 2023-10-06 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…

图像与视频处理 · 电气工程与系统科学 2023-03-21 Yinsheng He , Xingyu Li

Asthma is a chronic inflammatory disorder of the lower respiratory tract and naturally occurs in humans and animals including horses. The annotation of an asthma microscopy whole slide image (WSI) is an extremely labour-intensive task due…

The Segment Anything Model (SAM) marks a significant advancement in segmentation models, offering robust zero-shot abilities and dynamic prompting. However, existing medical SAMs are not suitable for the multi-scale nature of whole-slide…

计算机视觉与模式识别 · 计算机科学 2024-03-19 Hong Liu , Haosen Yang , Paul J. van Diest , Josien P. W. Pluim , Mitko Veta

Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

计算机视觉与模式识别 · 计算机科学 2020-09-30 Antoine Pirovano , Hippolyte Heuberger , Sylvain Berlemont , Saïd Ladjal , Isabelle Bloch

Autofocus is an important task for digital cameras, yet current approaches often exhibit poor performance. We propose a learning-based approach to this problem, and provide a realistic dataset of sufficient size for effective learning. Our…

计算机视觉与模式识别 · 计算机科学 2020-05-05 Charles Herrmann , Richard Strong Bowen , Neal Wadhwa , Rahul Garg , Qiurui He , Jonathan T. Barron , Ramin Zabih

Computer-aided pathology diagnosis based on the classification of Whole Slide Image (WSI) plays an important role in clinical practice, and it is often formulated as a weakly-supervised Multiple Instance Learning (MIL) problem. Existing…

计算机视觉与模式识别 · 计算机科学 2022-10-11 Linhao Qu , Xiaoyuan Luo , Manning Wang , Zhijian Song

Whole slide imaging provides a wide field-of-view (FOV) across cross-sections of biopsy or surgery samples, significantly facilitating pathological analysis and clinical diagnosis. Such high-quality images that enable detailed visualization…

光学 · 物理学 2024-07-31 Shi Zhao , Haowen Zhou , Siyu Lin , Ruizhi Cao , Changhuei Yang

Magnetic Resonance Imaging (MRI) is widely used in clinical practice, but suffered from prolonged acquisition time. Although deep learning methods have been proposed to accelerate acquisition and demonstrate promising performance, they rely…

图像与视频处理 · 电气工程与系统科学 2025-12-30 Hao Zhang , Qi Wang , Jian Sun , Zhijie Wen , Jun Shi , Shihui Ying

Digital pathology has advanced significantly over the last decade, with Whole Slide Images (WSIs) encompassing vast amounts of data essential for accurate disease diagnosis. High-resolution WSIs are essential for precise diagnosis but…

图像与视频处理 · 电气工程与系统科学 2024-08-28 Xuan Xu , Saarthak Kapse , Prateek Prasanna