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Expression of human epidermal growth factor receptor 2 (HER2) is an important biomarker in breast cancer patients who can benefit from cost-effective automatic Hematoxylin and Eosin (H\&E) HER2 scoring. However, developing such scoring…

计算机视觉与模式识别 · 计算机科学 2024-11-11 Rawan S. Abdulsadig , Bryan M. Williams , Nikolay Burlutskiy

Fine-grained classification of microscopic image data with limited samples is an open problem in computer vision and biomedical imaging. Deep learning based vision systems mostly deal with high number of low-resolution images, whereas…

计算机视觉与模式识别 · 计算机科学 2020-10-07 Mengran Fan , Tapabrata Chakrabort , Eric I-Chao Chang , Yan Xu , Jens Rittscher

Mammography and ultrasound are extensively used by radiologists as complementary modalities to achieve better performance in breast cancer diagnosis. However, existing computer-aided diagnosis (CAD) systems for the breast are generally…

图像与视频处理 · 电气工程与系统科学 2020-09-24 Gavriel Habib , Nahum Kiryati , Miri Sklair-Levy , Anat Shalmon , Osnat Halshtok Neiman , Renata Faermann Weidenfeld , Yael Yagil , Eli Konen , Arnaldo Mayer

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). However, existing approaches typically rely on pre-trained models from large natural image datasets, such as…

计算机视觉与模式识别 · 计算机科学 2023-03-24 Yi Lin , Zhongchen Zhao , Zhengjie ZHU , Lisheng Wang , Kwang-Ting Cheng , Hao Chen

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

图像与视频处理 · 电气工程与系统科学 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

计算机视觉与模式识别 · 计算机科学 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Cancers are the leading cause of death in many countries. Early diagnosis plays a crucial role in having proper treatment for this debilitating disease. The automated classification of the type of cancer is a challenging task since…

图像与视频处理 · 电气工程与系统科学 2021-08-20 Hosein Barzekar , Zeyun Yu

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

计算机视觉与模式识别 · 计算机科学 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

图像与视频处理 · 电气工程与系统科学 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

Breast cancer presents a significant healthcare challenge globally, demanding precise diagnostics and effective treatment strategies, where histopathological examination of Hematoxylin and Eosin (H&E) stained tissue sections plays a central…

图像与视频处理 · 电气工程与系统科学 2024-08-06 Linhao Qu , Chengsheng Zhang , Guihui Li , Haiyong Zheng , Chen Peng , Wei He

Breast cancer is the most diagnosed cancer and the most predominant cause of death in women worldwide. Imaging techniques such as the breast cancer pathology helps in the diagnosis and monitoring of the disease. However identification of…

图像与视频处理 · 电气工程与系统科学 2019-08-06 Francisco Perdigon Romero , An Tang , Samuel Kadoury

Machine learning (ML) is a branch of Artificial Intelligence (AI) where computers analyze data and find patterns in the data. The study focuses on the detection of metastatic cancer using ML. Metastatic cancer is the point where the cancer…

人工智能 · 计算机科学 2023-09-20 Bliss Singhal , Fnu Pooja

Breast cancer remains a leading cause of cancer-related mortality worldwide. Early detection is critical, yet manual histopathology analysis is complex and subject to inter-observer variability. While deep neural network-based diagnostic…

计算机视觉与模式识别 · 计算机科学 2026-03-17 Gul Sheeraz , Qun Chen , Liu Feiyu , Zhou Fengjin

Multiple instance learning (MIL) is an effective and widely used approach for weakly supervised machine learning. In histopathology, MIL models have achieved remarkable success in tasks like tumor detection, biomarker prediction, and…

Breast cancer remains a leading cause of cancer-related mortality among women worldwide. Ultrasound imaging, widely used due to its safety and cost-effectiveness, plays a key role in early detection, especially in patients with dense breast…

计算机视觉与模式识别 · 计算机科学 2025-09-08 Mohammad Abbadi , Yassine Himeur , Shadi Atalla , Wathiq Mansoor

Deep learning for medical image classification faces three major challenges: 1) the number of annotated medical images for training are usually small; 2) regions of interest (ROIs) are relatively small with unclear boundaries in the whole…

计算机视觉与模式识别 · 计算机科学 2019-10-23 Shaohua Li , Yong Liu , Xiuchao Sui , Cheng Chen , Gabriel Tjio , Daniel Shu Wei Ting , Rick Siow Mong Goh

The classification of histopathological images is of great value in both cancer diagnosis and pathological studies. However, multiple reasons, such as variations caused by magnification factors and class imbalance, make it a challenging…

计算机视觉与模式识别 · 计算机科学 2022-09-01 Yibao Sun , Xingru Huang , Yaqi Wang , Huiyu Zhou , Qianni Zhang

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Mammogram classification is directly related to computer-aided diagnosis of breast cancer. Traditional methods rely on regions of interest (ROIs) which require great efforts to annotate. Inspired by the success of using deep convolutional…

计算机视觉与模式识别 · 计算机科学 2017-05-25 Wentao Zhu , Qi Lou , Yeeleng Scott Vang , Xiaohui Xie