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Given the wide success of convolutional neural networks (CNNs) applied to natural images, researchers have begun to apply them to neuroimaging data. To date, however, exploration of novel CNN architectures tailored to neuroimaging data has…

计算机视觉与模式识别 · 计算机科学 2018-08-15 Pascal Sturmfels , Saige Rutherford , Mike Angstadt , Mark Peterson , Chandra Sripada , Jenna Wiens

The Cox model is an indispensable tool for time-to-event analysis, particularly in biomedical research. However, medicine is undergoing a profound transformation, generating data at an unprecedented scale, which opens new frontiers to study…

统计方法学 · 统计学 2023-03-07 Alexander W. Jung , Moritz Gerstung

Many problems within personalized medicine and digital health rely on the analysis of continuous-time functional biomarkers and other complex data structures emerging from high-resolution patient monitoring. In this context, this work…

机器学习 · 统计学 2025-01-14 Marcos Matabuena

Mathematical modelling of unemployment dynamics attempts to predict the probability of a job seeker finding a job as a function of time. This is typically achieved by using information in unemployment records. These records are right…

应用统计 · 统计学 2021-07-27 Pavle Boškoski , Matija Perne , Martina Rameša , Biljana Mileva Boshkoska

Objective: Convolutional neural networks (CNNs) have demonstrated promise in automated cardiac magnetic resonance image segmentation. However, when using CNNs in a large real-world dataset, it is important to quantify segmentation…

图像与视频处理 · 电气工程与系统科学 2023-01-02 Matthew Ng , Fumin Guo , Labonny Biswas , Steffen E. Petersen , Stefan K. Piechnik , Stefan Neubauer , Graham Wright

Accurate image registration is essential in many medical imaging applications, yet most deep registration networks provide little indication of when or where their predictions are unreliable. Existing uncertainty estimation approaches, such…

计算机视觉与模式识别 · 计算机科学 2026-02-03 Lin Tian , Xiaoling Hu , Juan Eugenio Iglesias

Bayesian neural networks (BNN) can estimate the uncertainty in predictions, as opposed to non-Bayesian neural networks (NNs). However, BNNs have been far less widely used than non-Bayesian NNs in practice since they need iterative NN…

机器学习 · 计算机科学 2022-02-15 Namuk Park , Taekyu Lee , Songkuk Kim

Treatment effect estimation in continuous time is crucial for personalized medicine. However, existing methods for this task are limited to point estimates of the potential outcomes, whereas uncertainty estimates have been ignored. Needless…

机器学习 · 计算机科学 2024-04-04 Konstantin Hess , Valentyn Melnychuk , Dennis Frauen , Stefan Feuerriegel

For the diagnostic inference under uncertainty Bayesian networks are investigated. The method is based on an adequate uniform representation of the necessary knowledge. This includes both generic and experience-based specific knowledge,…

人工智能 · 计算机科学 2022-10-11 Sebastian Flügge , Sandra Zimmer , Uwe Petersohn

In an era of large spectroscopic surveys of stars and big data, sophisticated statistical methods become more and more important in order to infer fundamental stellar parameters such as mass and age. Bayesian techniques are powerful methods…

太阳与恒星天体物理 · 物理学 2017-02-01 F. R. N. Schneider , N. Castro , L. Fossati , N. Langer , A. de Koter

In this paper, we present an uncertainty-aware INVASE to quantify predictive confidence of healthcare problem. By introducing learnable Gaussian distributions, we lever-age their variances to measure the degree of uncertainty. Based on the…

机器学习 · 计算机科学 2021-05-07 Jia-Xing Zhong , Hongbo Zhang

Clinician-facing predictive models are increasingly present in the healthcare setting. Regardless of their success with respect to performance metrics, all models have uncertainty. We investigate how to visually communicate uncertainty in…

人机交互 · 计算机科学 2022-10-25 Caitlin F. Harrigan , Gabriela Morgenshtern , Anna Goldenberg , Fanny Chevalier

Background: While deep learning technology, which has the capability of obtaining latent representations based on large-scale data, can be a potential solution for the discovery of a novel aging biomarker, existing deep learning methods for…

机器学习 · 计算机科学 2023-02-02 Seong-Eun Moon , Ji Won Yoon , Shinyoung Joo , Yoohyung Kim , Jae Hyun Bae , Seokho Yoon , Haanju Yoo , Young Min Cho

Aggregated health data such as claims data from health insurances become more and more available for research purposes. Estimates of excess mortality from prevalence and incidence of a chronic condition have only been possible for ages 50…

种群与进化 · 定量生物学 2019-08-13 Ralph Brinks

Changes over time in brain anatomy can provide important insight for treatment design or scientific analyses. We present a method that predicts how a brain MRI for an individual will change over time. We model changes using a diffeomorphic…

计算机视觉与模式识别 · 计算机科学 2020-06-02 Marianne Rakic , John Guttag , Adrian V. Dalca

Factors models are routinely used to analyze high-dimensional data in both single-study and multi-study settings. Bayesian inference for such models relies on Markov Chain Monte Carlo (MCMC) methods which scale poorly as the number of…

统计方法学 · 统计学 2025-04-29 Blake Hansen , Alejandra Avalos-Pacheco , Massimiliano Russo , Roberta De Vito

Variable selection has played a critical role in modern statistical learning and scientific discoveries. Numerous regularization and Bayesian variable selection methods have been developed in the past two decades for variable selection, but…

统计方法学 · 统计学 2024-03-04 Travis Canida , Hongjie Ke , Shuo Chen , Zhenayo Ye , Tianzhou Ma

Mathematical models are invaluable for understanding and predicting how biological systems behave, although their construction requires specifying mechanisms and relationships that are often not perfectly known. In the presence of multiple…

The accurate quantification of brain age from MRI has emerged as an important biomarker of brain health. However, existing approaches are often restricted to narrow age ranges and single-modality MRI data, limiting their capacity to capture…

图像与视频处理 · 电气工程与系统科学 2026-04-21 Dingyi Zhang , Ruiying Liu , Yun Wang

This work describes a Bayesian framework for reconstructing the boundaries that represent targeted features in an image, as well as the regularity (i.e., roughness vs. smoothness) of these boundaries.This regularity often carries crucial…