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The process of integration of inputs from several sensory modalities in the human brain is referred to as multisensory integration. Age-related cognitive decline leads to a loss in the ability of the brain to conceive multisensory inputs.…

信号处理 · 电气工程与系统科学 2023-05-02 Prerna Singh , Ayush Tripathi , Lalan Kumar , Tapan Kumar Gandhi

Dynamical models implemented on the large scale architecture of the human brain may shed light on how function arises from the underlying structure. This is the case notably for simple abstract models, such as the Ising model. We compare…

Predicting brain maturity using noninvasive magnetic resonance images (MRI) can distinguish different age groups and help to assess neurodevelopmental disorders. However, group-wise differences are often less informative for assessing…

神经元与认知 · 定量生物学 2014-12-17 Cheol E. Han , Luis R. Peraza , John-Paul Taylor , Marcus Kaiser

Neuroimaging-driven prediction of brain age, defined as the predicted biological age of a subject using only brain imaging data, is an exciting avenue of research. In this work we seek to build models of brain age based on functional…

Aging includes both continuous gradual decline from microscopic mechanisms together with major deficit onset events such as morbidity, disability and ultimately death. These deficit events are stochastic, obscuring the connection between…

定量方法 · 定量生物学 2025-12-25 Glen Pridham , Kenneth Rockwood , Andrew Rutenberg

Widespread interest in non-destructive biomarkers of aging has led to a curse of plenty: a multitude of biological ages that each proffers a 'true' health-adjusted age of an individual. While each measure provides salient information on the…

定量方法 · 定量生物学 2024-01-23 Glen Pridham , Andrew D. Rutenberg

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

The relaxation dynamics of many disordered systems, such as structural glasses, proteins, granular materials or spin glasses, is not completely frozen even at very low temperatures. This residual motion leads to a change of the properties…

软凝聚态物质 · 物理学 2009-10-31 Walter Kob , Francesco Sciortino , Piero Tartaglia

Synchronization of brain activity fluctuations is believed to represent communication between spatially distant neural processes. These inter-areal functional interactions develop in the background of a complex network of axonal connections…

神经元与认知 · 定量生物学 2016-11-10 Ariel Haimovici , Pablo Balenzuela , Enzo Tagliazucchi

Anatomic connections between brain areas affect information flow between neuronal circuits and the synchronization of neuronal activity. However, such structural connectivity does not coincide with effective connectivity, related to the…

神经元与认知 · 定量生物学 2015-06-03 Demian Battaglia , Annette Witt , Fred Wolf , Theo Geisel

We consider the formalism of information decomposition of target effects from multi-source interactions, i.e. the problem of defining redundant and synergistic components of the information that a set of source variables provides about a…

统计力学 · 物理学 2019-04-24 Daniele Marinazzo , Leonardo Angelini , Mario Pellicoro , Sebastiano Stramaglia

We present a neuronal network model inspired by the Ising model, where each neuron is a binary spin ($s_i = \pm1$) interacting with its neighbors on a 2D lattice. Updates are asynchronous and follow Metropolis dynamics, with a…

神经元与认知 · 定量生物学 2025-06-10 Sajedeh Sarmastani , Maliheh Ghodrat , Yousef Jamali

We numerically study the aging properties of the dynamical heterogeneities in the Ising spin glass. We find that a phase transition takes place during the aging process. Statics-dynamics correspondence implies that systems of finite size in…

The gradual accumulation of damage and dysregulation during the aging of living organisms can be quantified. Even so, the aging process is complex and has multiple interacting physiological scales -- from the molecular to cellular to whole…

定量方法 · 定量生物学 2021-05-06 Spencer Farrell , Garrett Stubbings , Kenneth Rockwood , Arnold Mitnitski , Andrew Rutenberg

Brain aging is a widely studied longitudinal process throughout which the brain undergoes considerable morphological changes and various machine learning approaches have been proposed to analyze it. Within this context, brain age prediction…

计算机视觉与模式识别 · 计算机科学 2020-11-30 Matthias Wilms , Jordan J. Bannister , Pauline Mouches , M. Ethan MacDonald , Deepthi Rajashekar , Sönke Langner , Nils D. Forkert

Using Monte Carlo simulations, we have studied isothermal aging of three-dimensional Ising spin-glass model focusing on quasi-equilibrium behavior of the spin auto-correlation function. Weak violation of the time translational invariance in…

无序系统与神经网络 · 物理学 2009-10-31 Tatsuo Komori , Hajime Yoshino , Hajime Takayama

Cognitive ageing seems to be a story of global degradation. As one ages there are a number of physical, chemical and biological changes that take place. Therefore it is logical to assume that the brain is no exception to this phenomenon.…

适应与自组织系统 · 物理学 2014-08-07 Sakyasingha Dasgupta

This article introduces a predictor-dependent joint modeling framework for network data obtained from multiple subjects over a shared set of nodes with spatial co-ordinates and spatially correlated nodal attributes. The framework is highly…

As the human brain develops, it increasingly supports coordinated control of neural activity. The mechanism by which white matter evolves to support this coordination is not well understood. We use a network representation of diffusion…

We study and compare equilibrium and aging dynamics on both sides of the ideal glass transition temperature $T_{MCT}$. In the context of a mean field model, we observe that all dynamical behaviors are determined by the energy distance…

无序系统与神经网络 · 物理学 2009-10-06 Alexandre Lefèvre
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