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Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia, affecting memory, reasoning, communication, and daily functioning. Early diagnosis is particularly important, as timely intervention may…

声音 · 计算机科学 2026-05-26 Loukas Ilias , Dimitris Askounis

The Temporal Sampling Framework (TSF) theorizes that the characteristic phonological difficulties of dyslexia are caused by an atypical oscillatory sampling at one or more temporal rates. The LEEDUCA study conducted a series of…

Alzheimers disease is a deadly neurological condition, impairing important memory and brain functions. Alzheimers disease promotes brain shrinkage, ultimately leading to dementia. Dementia diagnosis typically takes 2.8 to 4.4 years after…

Timely and accurate assessment of cognitive impairment remains a major unmet need. Speech biomarkers offer a scalable, non-invasive, cost-effective solution for automated screening. However, the clinical utility of machine learning (ML)…

Retinal vascular diseases affect the well-being of human body and sometimes provide vital signs of otherwise undetected bodily damage. Recently, deep learning techniques have been successfully applied for detection of diabetic retinopathy…

机器学习 · 计算机科学 2022-01-05 Guan Wang , Yusuke Kikuchi , Jinglin Yi , Qiong Zou , Rui Zhou , Xin Guo

Predicting future disease progression risk from medical images is challenging due to patient heterogeneity, and subtle or unknown imaging biomarkers. Moreover, deep learning (DL) methods for survival analysis are susceptible to image domain…

Childhood myopia constitutes a significant global health concern. It exhibits an escalating prevalence and has the potential to evolve into severe, irreversible conditions that detrimentally impact familial well-being and create substantial…

Monocular depth estimation, which plays a crucial role in understanding 3D scene geometry, is an ill-posed problem. Recent methods have gained significant improvement by exploring image-level information and hierarchical features from deep…

计算机视觉与模式识别 · 计算机科学 2018-06-08 Huan Fu , Mingming Gong , Chaohui Wang , Kayhan Batmanghelich , Dacheng Tao

Autism Spectrum Disorder (ASD) is a lifelong condition that significantly influencing an individual's communication abilities and their social interactions. Early diagnosis and intervention are critical due to the profound impact of ASD's…

计算与语言 · 计算机科学 2024-09-04 Jihyun Mun , Sunhee Kim , Minhwa Chung

Autism Spectrum Disorder significantly influences the communication abilities, learning processes, behavior, and social interactions of individuals. Although early intervention and customized educational strategies are critical to improving…

机器学习 · 计算机科学 2025-10-10 Nelaka K. A. R , Peiris M. K. , Liyanage R. P. B

Regression discontinuity design (RDD) is a quasi-experimental approach to study the causal effects of an intervention/treatment on later health outcomes. It exploits a continuously measured assignment variable with a clearly defined cut-off…

应用统计 · 统计学 2024-06-28 Maja Popovic , Daniela Zugna , Lorenzo Richiardi

Opioid related aberrant behaviors (ORABs) present novel risk factors for opioid overdose. This paper introduces a novel biomedical natural language processing benchmark dataset named ODD, for ORAB Detection Dataset. ODD is an…

The delta-bar-delta algorithm is recognized as a learning rate adaptation technique that enhances the convergence speed of the training process in optimization by dynamically scheduling the learning rate based on the difference between the…

机器学习 · 计算机科学 2023-10-18 Zhao Song , Chiwun Yang

Collecting and accessing a large amount of medical data is very time-consuming and laborious, not only because it is difficult to find specific patients but also because it is required to resolve the confidentiality of a patient's medical…

声音 · 计算机科学 2021-03-04 Junghyun Koo , Jie Hwan Lee , Jaewoo Pyo , Yujin Jo , Kyogu Lee

Background: Conventional prediction methods such as logistic regression and gradient boosting have been widely utilized for disease onset prediction for their reliability and interpretability. Deep learning methods promise enhanced…

Alzheimer's Dementia (AD) is an incurable, debilitating, and progressive neurodegenerative condition that affects cognitive function. Early diagnosis is important as therapeutics can delay progression and give those diagnosed vital time.…

机器学习 · 计算机科学 2023-02-28 Thomas Searle , Zina Ibrahim , Richard Dobson

While the brain connectivity network can inform the understanding and diagnosis of developmental dyslexia, its cause-effect relationships have not yet enough been examined. Employing electroencephalography signals and band-limited white…

神经元与认知 · 定量生物学 2023-01-03 I. RodrÍguez-RodrÍguez , A. Ortiz , N. J. Gallego-Molina , M. A. Formoso , W. L. Woo

Bronchopulmonary dysplasia (BPD) is a chronic lung disease affecting 35% of extremely low birth weight infants. Defined by oxygen dependence at 36 weeks postmenstrual age, it causes lifelong respiratory complications. However, preventive…

Alzheimer's Disease (AD) ravages the cognitive ability of more than 5 million Americans and creates an enormous strain on the health care system. This paper proposes a machine learning predictive model for AD development without medical…

定量方法 · 定量生物学 2020-06-17 Courtney Cochrane , David Castineira , Nisreen Shiban , Pavlos Protopapas

Mismatch negativity (MMN) in humans reflects deviance detection (DD), a core neural mechanism of predictive processing. However, the fundamental principles by which DD emerges and matures during early cortical development-potentially…

神经元与认知 · 定量生物学 2025-10-02 Zhuo Zhang , Amit Yaron , Dai Akita , Tomoyo Isoguchi Shiramatsu , Zenas C. Chao , Hirokazu Takahashi