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A boundary element implementation of the regularised Stokeslet method of Cortez is applied to cilia and flagella-driven flows in biology. Previously-published approaches implicitly combine the force discretisation and the numerical…

流体动力学 · 物理学 2010-08-04 David J. Smith

Cilia and flagella in biological systems often show large scale cooperative behaviors such as the synchronization of their beats in "metachronal waves". These are beautiful examples of emergent dynamics in biology, and are essential for…

软凝聚态物质 · 物理学 2016-04-20 Nicolas Bruot , Pietro Cicuta

Natural cilia are hair-like microtubule-based structures that are able to move fluid at low Reynolds number through asymmetric motion. In this paper we follow a biomimetic approach to design artificial cilia lining the inner surface of…

流体动力学 · 物理学 2009-09-30 S. N. Khaderi , M. G. H. M. Baltussen , P. D. Anderson , D. Ioan , J. M. J. den Toonder , P. R. Onck

Ciliated organs transport viscous fluids through confined ducts, yet how duct morphology and ciliary activity jointly set the limits of flow rate and sustainable pressure remains unclear. Here, we model dense arrays of beating cilia lining…

流体动力学 · 物理学 2026-05-22 JP Raimondi , Feng Ling , Eva Kanso

Cilia and flagella are actively bending slender organelles, performing functions such as motility, feeding and embryonic symmetry breaking. We review the mechanics of viscous-dominated microscale flow, including time-reversal symmetry, drag…

定量方法 · 定量生物学 2013-09-06 Thomas D. Montenegro-Johnson , Andrew A. Smith , David J. Smith , Daniel Loghin , John R. Blake

We present a novel platform for the large-scale simulation of fibrous structures immersed in a Stokesian fluid and evolving under confinement or in free-space. One of the main motivations for this work is to study the dynamics of fiber…

数值分析 · 数学 2017-01-04 Ehssan Nazockdast , Abtin Rahimian , Denis Zorin , Michael Shelley

Cellular appendages conferring motility, such as flagella or cilia, are known to synchronise their periodic beats. The origin of synchronisation is a combination of long-range hydrodynamic interactions with physical mechanisms allowing the…

生物物理 · 物理学 2021-04-21 Ivan Tanasijević , Eric Lauga

To gain insight into the nature of biological synchronization at the microscopic scale, we here investigate the hydrodynamic synchronization between conically rotating objects termed nodal cilia. A mechanical model of three rotating cilia…

软凝聚态物质 · 物理学 2018-03-28 Keiji Okumura , Seiya Nishikawa , Toshihiro Omori , Takuji Ishikawa , Atsuko Takamatsu

Geometric confinement plays an important role in the dynamics of natural and synthetic microswimmers from bacterial cells to self-propelled particles in high-throughput microfluidic devices. However, little is known about the effects of…

流体动力学 · 物理学 2014-11-13 Alan Cheng Hou Tsang , Eva Kanso

Synchronization of actively oscillating organelles such as cilia and flagella facilitates self-propulsion of cells and pumping fluid in low Reynolds number environments. To understand the key mechanism behind synchronization induced by…

软凝聚态物质 · 物理学 2015-05-20 Nariya Uchida , Ramin Golestanian

We develop a numerical framework to simulate the locomotion of a flagellated bacterium with a spheroidal head (such as Escherichia coli) in biological fluids like mucus, which are entangled polymer solutions exhibiting elasto-viscoplastic…

流体动力学 · 物理学 2026-04-01 Arjun Sharma , Sabarish V. Narayanan , Sarah Hormozi , Donald L. Koch

Cellular appendages such as cilia and flagella represent universal tools enabling cells and microbes, among other essential functionalities, to propel themselves in diverse environments. In its planktonic, i.e. freely swimming, state the…

We study the settling of solid particles within a viscous incompressible fluid contained in a two-dimensional channel, where the mass density of the particles is slightly greater than that of the fluid. The fluid-structure interaction…

流体动力学 · 物理学 2015-09-07 Sudeshna Ghosh , John M. Stockie

The deformations of flagella are important in the motility of single- and multi-flagellated bacteria. Existing numerical methods have treated flagella as extensible filaments with a large extensional modulus, resulting in a stiff numerical…

流体动力学 · 物理学 2020-07-15 Mehdi Jabbarzadeh , Henry C. Fu

We present a new method for the geometric reconstruction of elastic surfaces simulated by the immersed boundary method with the goal of simulating the motion and interactions of cells in whole blood. Our method uses parameter-free radial…

数值分析 · 数学 2022-08-31 Andrew Kassen , Aaron Barrett , Varun Shankar , Aaron L. Fogelson

The hydrodynamic interactions among bacterial cell bodies, flagella, and surrounding boundaries are essential for understanding bacterial motility in complex environments. In this study, we demonstrate that each slender flagellum can be…

软凝聚态物质 · 物理学 2025-01-07 Baopi Liu , Lu Chen , Ji Zhang

Fluid dynamics between a particle-laden flow and an evolving boundary are found in various contexts. We numerically simulated the morphodynamics of silica particle deposition from flowing water within geothermal heat exchangers using the…

流体动力学 · 物理学 2018-01-09 James N. Hewett , Mathieu Sellier

There are many interesting physical processes which involve the generation of high density plasmas in large volumes. However, when modeling these systems numerically, the large densities and volumes present a significant computational…

计算物理 · 物理学 2007-05-23 A. E. Schulz , A. D. Greenwood , K. L. Cartwright , P. J. Mardahl

Cilia and flagella are hair-like appendages that protrude from the surface of a variety of eukaryotic cells and deform in a wavelike fashion to transport fluids and propel cells. Motivated by the ubiquity of non-Newtonian fluids in biology,…

流体动力学 · 物理学 2014-03-19 J. Rodrigo Vélez-Cordero , Eric Lauga

The Immersed Boundary (IB) method is a widely-used numerical methodology for the simulation of fluid-structure interaction problems. The IB method utilizes an Eulerian discretization for the fluid equations of motion while maintaining a…

数值分析 · 数学 2012-10-09 Varun Shankar , Grady B. Wright , Aaron L. Fogelson , R. M. Kirby
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